Health Studies: Vigorous Daily Exercise Increases Neurotropins, Boosting Cognitive Function

From the Journal of Sport and Health Science:

Therefore, promotion of adequate volumes and intensities of physical exercise (i.e., approximately 3 months of moderate-intensity aerobic exercise, with 2–3 sessions/week lasting not less than 30 min) represents an inexpensive and safe strategy for boosting BDNF (brain-derived neurotrophic factor) release that may preserve or restore cognitive function.

Updated overview on interplay between physical exercise, neurotrophins, and cognitive function in humans Journal Of Sport and Health Science Jan 2020

Taken together, the currently available data seemingly confirm the existence of a positive relationship between physical exercise and circulating BDNF levels, both in the short and long term, and also support the beneficial impact of training programs for amplifying the acute BDNF response.

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New Books: “A Journey Through Wine And Food”

A Journey Through Wine and Food - A Collection of Wine and Food Pairings Jerilyn Zaveral and Carla Anderson January 2020A Journey Through Wine and Food is a total sensory experience with its lifelike photography, stunning presentation of each dish, glimpses into the wineries and their winemakers, histories of the Central Valley wine region, and most of all amazing recipes that will transform everyday meals into priceless celebrations for any occasion! Inspirational quotes can also be found throughout as a reminder that not only do we need food to nourish our bodies, but we need the company of those on our journey to nourish out souls.

From Shrimp Tacos and Rose, to Beef Bourguignon with Burgundy, to Chocolate Cake paired with Port, A Journey Through Wine and Food gives everyone an opportunity to enhance their experience in the kitchen, regardless of skill level, and takes the guess work out of which wines to pair with dinner. It will also take you on a journey through The Central Valley wine regions of California giving you a sneak peek at some of the best wineries in the world, which until now could be considered “hidden gems.”

Jerilyn Zaveral was born and raised in Central California where she continues to live with her husband Joe and their dog, Hogan. Other than a short stay in New York when she wrote her first cookbook and opened her first cafe, her heart and home have always been in the San Joaquin Valley where she enjoys cooking for family and friends and tasting fine wines. She has won several awards in cooking competitions and cook-offs. Most notably her cafe “Z Spice of Life” was recognized as a destination spot in the Hudson Valley Explorer’s Guide. Jerilyn’s love of creating recipes and meals began when she was a very young child in her grandmother’s kitchen. More specifically, it was one afternoon while baking a chocolate cake when her grandmother asked her to get out the mayonnaise…the realization instantly took hold that cooking isn’t always about the end product, but about the journey of discovering unique tastes, textures and combinations of flavors that others might not expect.

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Fasting Activates Sirtuin Signaling Proteins (SIRT1), Accelerating Cell Repair

Sirtuins are a family of signaling proteins involved in metabolic regulation. SIRT1 (along with SIRT6 and SIRT7) are proteins are employed in DNA repair.

 

Sirtuins - SIRT1 Activator Nature Reviews Drug Discovery

From Wikipedia:

Sirtuins are a class of proteins that possess either mono-ADP-ribosyltransferase, or deacylase activity, including deacetylase, desuccinylase, demalonylase, demyristoylase and depalmitoylase activity. The name Sir2 comes from the yeast gene ‘silent mating-type information regulation 2‘, the gene responsible for cellular regulation in yeast.

From in vitro studies, sirtuins are implicated in influencing cellular processes like aging, transcription, apoptosis, inflammation and stress resistance, as well as energy efficiency and alertness during low-calorie situations. As of 2018, there was no clinical evidence that sirtuins affect human aging.

Aging

Although preliminary studies with resveratrol, an activator of deacetylases such as SIRT1, led some scientists to speculate that resveratrol may extend lifespan, there was no clinical evidence for such an effect, as of 2018.

In vitro studies shown that calorie restriction regulates the plasma membrane redox system, involved in mitochondrial homeostasis, and the reduction of inflammation through cross-talks between SIRT1 and AMP-activated protein kinase (AMPK), but the role of sirtuins in longevity is still unclear, as calorie restriction in yeast could extend lifespan in the absence of Sir2 or other sirtuins, while the in vivo activation of Sir2 by calorie restriction or resveratrol to extend lifespan has been challenged in multiple organisms.

 

Video Interviews: 67-Year Old Singer David Byrne

David Byrne is burning down the house on Broadway. His show “American Utopia” is a smash hit, but that isn’t the only reason the former frontman for the Talking Heads is so happy. Serena Altschul talks with Byrne about his love of performing, his growing affinity for collaboration, and his optimism, apparent in his “Reasons to Be Cheerful,” a platform that spotlights ways in which the world is getting better.

Books On Aging: “Old Man Country” – Thomas R. Cole

Old Man Country My Search for Meaning Among The Elders Thomas R. Cole December 2019The book follows the journey of a writer in search of wisdom, as he encounters twelve distinguished American men over 80 — including Paul Volcker, the former head of the Federal Reserve, and Denton Cooley, the world’s most famous heart surgeon. In these and other intimate conversations, the book explores and honors the particular way that each man faces four challenges of living a good old age: Am I still a man? Do I still matter? What is the meaning of my life? Am I loved? 

We aspire to live in a country where old men are celebrated as vital elders but not demeaned if they become ill and dependent. We aspire to maintain health as well as maintain dignity and fulfillment in frailty. Old Man Country helps readers see and imagine these possibilities for themselves.

Review of book in Houston Chronicle

Readers will come to see how each man — even the most famous — faces universal challenges. Personal stories about work, love, sexuality, and hope mingle with stories about illness, loss and death. This book will strengthen each of us as we and our loved ones anticipate and navigate our way through the passages of old age.

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Retirement: 53-Story “The Clare” Tower Sale Signals Booming “Senior Luxury Living” Sector In Chicago

From a The Real Deal online article:

A unit at the Clare costs an average one-time entrance fee of $800,000 or so, along with around $5,500 monthly fees. The entrance fee is refunded when a resident dies or moves out. Entrance fees at a typical senior living facility is around $369,000.

The 53-story Clare tower on Chicago’s Magnificent Mile has sold for $105 million, a sign that luxury senior living facilities hold huge upside in today’s market.

Fundamental Advisors LP sold the luxury seniors-only tower for twice what the private equity firm paid for the 334-unit tower in 2012, according to the Wall Street Journal.

“The Clare” website 

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Classic Cars: 1954 Ford Crestline “Skyliner” Featured A Glass Roof

From a Classic Driver online listing:

1954 Ford Crestline Skyliner Classic DriverIn 1954, Ford added a new niche model to the top-of-the-line Crestline series : the Skyliner. The car had a glass roof section over the front seats, made of blue-green tinted acrylic and letting a diffused yet filtered light through. Ford claimed that 60% of the sunrays were filtered out.

The Skyliner offered a very light interior, with a soft green glow : the perfect car for the drive-in cinema, and a a great view of the future’s past, developed in an era obsessed with Jet Age design features. The Skyliner was only in production for one year, and in total 13.144 examples were sold.

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