More than 2.8 million antibiotic-resistant infections occur in the United States each year, and more than 35,000 people die as a result. In addition, nearly 223,900 people in the United States required hospital care for C. difficile and at least 12,800 people died in 2017.
Germs continue to spread and develop new types of resistance, and progress may be undermined by some community-associated infections that are on the rise. More action is needed to address antibiotic resistance. While the development of new treatments is one of these key actions, such investments must be coupled with dedicated efforts toward preventing infections in the first place, slowing the development of resistance through better antibiotic use, and stopping the spread of resistance when it does develop to protect American lives now and in the future.
CDC’s Antibiotic Resistance Threats in the United States, 2019 (2019 AR Threats Report) includes updated national death and infection estimates that underscore the continued threat of antibiotic resistance in the United States. New CDC data show that while the burden of antibiotic-resistance threats in the United States was greater than initially understood, deaths are decreasing since the 2013 report. This suggests that U.S. efforts—preventing infections, stopping spread of bacteria and fungi, and improving use of antibiotics in humans, animals, and the environment—are working, especially in hospitals. Vaccination, where possible, has also shown to be an effective tool of preventing infections, including those that can be resistant, in the community.
Vineyards in Colorado are mostly nestled in the temperate, high elevation river valleys and mesas of Mesa and Delta counties, with some acreage in Montezuma county. Colorado’s grape growing regions range in elevation from 4,000 to 7,000 feet and are thus among the highest vineyards in the world, resulting in hot days accompanied by cool nights.
The ‘continental climate’ in these regions create day to night temperature variations topically ranging from 25 to 30 degrees during the grape maturation months of August and September. The long warm daylight hours of intense high-altitude sunlight mature the fruit completely and build the natural sugars. The cool evenings cause the grapes to retain the acids so vital to premium winemaking. However, the high altitude can also present a challenge to grape growers, in that the average frost free growing season ranges from 150 to 182 days.
The 12,000-square-foot store is packed with in-store dining options, a scratch bakery, coffee bar and a curated assortment of fresh and local products. An additional 8,000 square feet is dedicated to prep space and a kitchen where employees make prepared foods and from-scratch items using Brothers Marketplace’s own recipes.
Roche Bros.’ Brothers Marketplace banner opened its newest store in Cambridge, Massachusetts Tuesday. It’s the banner’s fifth location to open since the concept debuted in 2014, and joins other Brothers stores in Cambridge, Duxbury, Medfield, Weston and Waltham, Massachusetts.
A full-service butcher counter allows customers to place special orders, make requests or order preferred cuts. The butcher sells only antibiotic-free and hormone-free meats and poultry, and includes selections like certified Angus Prime Beef as well as pork sourced from Niman Ranch, and Bell and Evans chicken. The counter also offers ready-to-cook options such as marinated meats, kabobs and house-made sausages.
First published in 1897, Country Life is itself a late-Victorian institution. What could be more appropriate, therefore, than to celebrate this anniversary with a collector’s issue of articles and photographs from the magazine’s archives?
An opening timeline offers an overview of the Victorian Age, but the focus of what follows is exclusively architectural. The coverage of country houses has always been central to the magazine, but it can also claim to have been a pioneer in the study of Victorian architecture through the work of two former Architectural Editors, Mark Girouard and Michael Hall.
This year is the 200th anniversary of the birth of both Queen Victoria and Prince Albert, respectively in May and August, 1819. Their marriage 21 years later in 1840 was long arranged and, after a difficult beginning, grew to be unexpectedly happy. With perfect symmetry, it lasted 21 years, until Prince Albert’s early death in 1861.
Lauren lived his life as a character in his own movie, and his clothes allowed his customers to do the same. Some days he was Rick from Casablanca, dressed in a double-breasted white dinner jacket, and other days he was a cowboy, wearing jeans and cowboy boots with a blazer.
Ralph Lauren is “zee American designer,” says Karl Lagerfeld in Very Ralph, a new HBO documentary on the Bronx-born fashion icon. Coming from zee most prolific French designer of the 20th and 21st centuries, that’s saying a lot. But the film, which premiers today, supports that statement, illustrating with interviews and archival footage how he’s successfully sold an American fantasy to a global audience for over 50 years.
“When you live paycheck to paycheck, there are times you fall behind. There was a healthy dose of fear, but I knew that my business would grow if I kept pushing.” Getting an M.B.A. felt superfluous. “I would rather be paid to learn,” he said. “There’s not a lot you can learn in an M.B.A. program that you can’t learn online or through other mechanisms. I’m not a big fan of taking those years and spending money that you could put to better use.”
Billionaire tech entrepreneur Mark Cuban discusses value of real-world education, Trump, Warren, and sexual harassment on his NBA team.
(The) former high-tech executive and celebrity entrepreneur… may be one of the few people who can get away with telling a packed auditorium of Harvard Business School (HBS) students that getting an M.B.A. is a “mistake these days” — and get a round of applause in response.
In Ian Fleming’s From Russia, With Love, there is a terrific exchange between James Bond and Tatiana Romanova — a Soviet corporal who takes up with the British agent. On a sleeper train out of Turkey, the two are readying themselves for the day ahead and Romanova, noticing that 007 doesn’t wear cologne, asks him why this is.
“We wash,” replies Bond, drier than a martini. And this clean-cut, neatly clipped and slightly stinging response sums up the superspy’s attitude to his grooming routine. It’s a thoroughly English approach; leaning on trusted, heritage brands — and not preoccupied with overly strong scents or convoluted bits of kit. So this got us thinking: if a pared-back, simple grooming routine was good enough for MI6’s finest, surely it should be good enough for us?
Director of Photography – Christophe Collette
Underwater DoP – Vincent Kardasik
Executive producer – Blaise Izard
Line Producer – Manu Henoque
Editor Andreas – Arvidsson
Composer – Gustav Karlström
Sound design – Anton Ahlberg
Colorist – Nicke Jacobsson
Production co – badassfilms.tv
“Daughter of the Sea” is a short film exploring a fishermans relationship with his daughter and the sea. Shot in the French town St Jean de Luz.