From a Harvard Gazette online article:
“When you live paycheck to paycheck, there are times you fall behind. There was a healthy dose of fear, but I knew that my business would grow if I kept pushing.” Getting an M.B.A. felt superfluous. “I would rather be paid to learn,” he said. “There’s not a lot you can learn in an M.B.A. program that you can’t learn online or through other mechanisms. I’m not a big fan of taking those years and spending money that you could put to better use.”
Billionaire tech entrepreneur Mark Cuban discusses value of real-world education, Trump, Warren, and sexual harassment on his NBA team.
(The) former high-tech executive and celebrity entrepreneur… may be one of the few people who can get away with telling a packed auditorium of Harvard Business School (HBS) students that getting an M.B.A. is a “mistake these days” — and get a round of applause in response.
To read more: https://news.harvard.edu/gazette/story/2019/11/mark-cuban-and-jeff-flake-discuss-the-economy/?utm_source=SilverpopMailing&utm_medium=email&utm_campaign=Daily%20Gazette%2020191114%20(1)
From a Harvard news online release:
“This study identifies a new molecular connection between exercise and inflammation that takes place in the bone marrow and highlights a previously unappreciated role of leptin in exercise-mediated cardiovascular protection,” said Michelle Olive, program officer at the National Heart, Lung, and Blood Institute Division of Cardiovascular Sciences. “This work adds a new piece to the puzzle of how sedentary lifestyles affect cardiovascular health and underscores the importance of following physical-activity guidelines.”
Scientists at Harvard-affiliated Massachusetts General Hospital (MGH) have identified a previously unknown biological pathway that promotes chronic inflammation and may help explain why sedentary people have an increased risk for heart disease and strokes.
In a study to be published in the November issue of Nature Medicine, MGH scientists and colleagues at several other institutions found that regular exercise blocks this pathway. This discovery could aid the development of new therapies to prevent cardiovascular disease.
To read more: https://news.harvard.edu/gazette/story/2019/11/exercise-found-to-block-chronic-inflammation-in-mice/
From a Harvard news online release:
“The results we saw were stunning and suggest that holistically addressing aging via gene therapy could be more effective than the piecemeal approach that currently exists,” said first author Noah Davidsohn, a former research scientist at the Wyss Institute and HMS who is now chief technology officer of Rejuvenate Bio. “Everyone wants to stay as healthy as possible for as long as possible, and this study is a first step toward reducing the suffering caused by debilitating diseases.”
New research from the Wyss Institute for Biologically Inspired Engineering at Harvard University and Harvard Medical School (HMS) suggests that it may be possible someday to tend to multiple ailments with one treatment.
The study was conducted in the lab of Wyss core faculty member George Church as part of Davidsohn’s postdoctoral research into the genetics of aging. Davidsohn, Church, and their co-authors homed in on three genes that had been shown to confer increased health and lifespan benefits in mice that were genetically engineered to overexpress them: FGF21, sTGFβR2, and αKlotho. They hypothesized that providing extra copies of those genes to nonengineered mice via gene therapy would similarly combat age-related diseases and bring health benefits.
To read more: https://news.harvard.edu/gazette/story/2019/11/researchers-able-to-improve-reverse-age-related-diseases-in-mice/?utm_source=SilverpopMailing&utm_medium=email&utm_campaign=Daily%20Gazette%2020191105%20(1)
From a Sleep Review Magazine online article:
When people are awake during the night, their behaviors are often mismatched with their internal body clocks. This can lead to nighttime eating, which can influence the way the body processes sugar and could lead to a higher risk in diabetes. “What happens when food is eaten when you normally should be fasting?” Scheer asked the audience. “What happens is that your glucose tolerance goes out the window….So your glucose levels after a meal are much higher.” This can increase people’s risk for diabetes.
Frank Scheer, PhD, professor of medicine at Harvard Medical School and director of the medical chronobiology program at Brigham and Women’s Hospital in Boston, says disruption of the body’s circadian rhythms may be one major reason why more Americans are living with preventable diseases. During his keynote talk at the 2019 AAST annual meeting in St. Louis, he outlined how recent research supports the hypothesis that higher rates of shiftwork and other forms of nighttime disruption could be contributing to increased rates of obesity, diabetes, and other common ailments.
To read more: http://www.sleepreviewmag.com/2019/10/circadian-rhythm-disruption-increase-preventable-diseases/
From a Harvard Joint Center for Housing Studies report:
As both the number and share of older households in the United States increase to unprecedented levels, inequalities are becoming more evident. Within the 65-and-over age group, most recent income gains have gone to the highest earners, and the number of households with housing cost burdens has reached an all-time high. Ensuring that middle- and lower-income households in this age range have the means to live affordably and safely in their current homes or move to other suitable housing will be a growing challenge.
Meanwhile, many households in the 50–64 year-old age group have not recovered from the Great Recession, leaving them with lower incomes and homeownership rates than their predecessors at similar ages. For the nearly 10 million households in this age group that are cost burdened, ensuring financial and housing security in retirement will be a struggle.
From a HarvardMagazine.com online archive article:
Six factors measured by age 50 were excellent predictors of those who would be in the “happy-well” group–the top quartile of the Harvard men–at age 80: a stable marriage, a mature adaptive style, no smoking, little use of alcohol, regular exercise, and maintenance of normal weight. At age 50, 106 of the men had five or six of these factors going for them, and at 80, half of this group were among the happy-well. Only eight fell into the “sad-sick” category, the bottom quarter of life outcomes. In contrast, of 66 men who had only one to three factors at age 50, not a single one was rated happy-well at 80. In addition, men with three or fewer factors, though still in good physical health at 50, were three times as likely to be dead 30 years later as those with four or more.
The book examines the lives of a group of Harvard men who have been studied from their college years all the way to retirement and, in some cases, death. Its cornerstone is the Grant Study, a longitudinal investigation conceived in 1937 and launched at Harvard in 1939. With funding from dime-store magnate W. T. Grant, researchers signed up 268 members of the classes of 1941 through 1944, in their sophomore years, for an in-depth, lifelong study of “normal” adult development.
To read more click on the following link: https://harvardmagazine.com/2019/08/the-talent-for-aging-well