Science Podcasts: Fruit Fly Neural Circuits, Fuzzy Moth Acoustics And Metallic Glass (Nature)

Nature PodcastsThis week, the brain pathways of egg laying in fruit flies, preventing fractures in metallic glass, moth’s fuzz as superior acoustic camouflage and a coronavirus update.

In this episode:

00:46 Working out the wiring behind fruit fly behaviour

Researchers have identified a neural circuit linking mating and egg laying in female fruit flies. Research Article: Wang et al.

06:01 Research Highlights

Ancient, cave-dwelling cockroaches, and hairy moths dampen sound. Research Highlight: Cockroaches preserved in amber are the world’s oldest cave dwellers; Research Highlight: Stealth flyers: moths’ fuzz is superior acoustic camouflage

07:57 Making better metallic glass

Metallic glasses have many desirable properties, but these materials are prone to fracturing. Now, a new manufacturing process may have overcome this issue. Research article: Pan et al.News and Views: Metallic glasses rejuvenated to harden under strain

13:47 News Chat

Coronavirus outbreak updates, a survey shows Indian bird numbers are in decline, and the genomes of New York rats. News: Coronavirus: latest news on spreading infectionNews: Hundreds of bird species in India are decliningNews: Genomes reveal how New York City’s rats thrive in the urban jungle

Digital Health: Wearable Sensor Data Can Predict Heart Failure 6 Days Before Hospitalization

From a “Circulation: Heart Failure” Journal study (Feb 25, 2020):

Circulation Heart Failure logoThe study shows that wearable sensors coupled with machine learning analytics have predictive accuracy comparable to implanted devices.

We demonstrate that machine learning analytics using data from a wearable sensor can accurately predict hospitalization for heart failure exacerbation…at a median time of 6.5 days before the admission.

Heart failure (HF) is a major public health problem affecting >23 million patients worldwide. Hospitalization costs for HF represent 80% of costs attributed to HF care. Thus, accurate and timely detection of worsening HF could allow for interventions aimed at reducing the risk of HF admission.

Data collected by the sensor are streamed to a phone and then encrypted and uploaded to a cloud analytics platform.
Data collected by the sensor are streamed to a phone and then encrypted and uploaded to a cloud analytics platform.

Several such approaches have been tested. Tracking of daily weight, as recommended by current HF guidelines, did not lead to reduction of the risk of HF hospitalization, most likely because the weight gain is a contemporaneous or lagging indicator rather than a leading event. Interventions based on intrathoracic impedance monitoring also did not result in reduction of readmission risk. The results suggest that physiological parameters other than weight or intrathoracic impedance in isolation may be needed to detect HF decompensation in a timely manner. In fact, 28% reduction of rehospitalization rates has been shown with interventions based on pulmonary artery hemodynamic monitoring. More recently, in the MultiSENSE study (Multisensor Chronic Evaluation in Ambulatory HF Patients), an algorithm based on physiological data from sensors in the implantable cardiac resynchronization therapy defibrillators, was shown to have 70% sensitivity in predicting the risk of HF hospitalization or outpatient visit with intravenous therapies for worsening of HF.

Read full study

Politics: “South Carolina Democratic Debate Recap”

Seven candidates took the stage Tuesday, often talking over one another as they faced off in the final Democratic debate before the South Carolina primary and Super Tuesday. NPR’s Domenico Montanaro and Danielle Kurtzleben take a look at some of the top moments. •

Read “4 Takeaways From The South Carolina Democratic Debate” 

Exhibitions: Inside Look At “Picasso And Paper”, Royal Academy Of Arts (Video)

Join Curator Ann Dumas for a view inside the ‘Picasso and Paper’ exhibition, which features works spanning the artist’s entire career. Can you guess which work the artist made when he was just nine years old?

Website

Media: “Smithsonian Open Access” – 2.8 Million Images Into Public Domain

People everywhere can now download, remix and share Smithsonian Open Access content for any purpose, for free, from portraits of historic Americans to 3D scans of dinosaur fossils. What will you create, imagine and discover?

Website

Travel Videos: “Namibia” By Marcello Ercole (2020)

Directed, Filmed, Edited by: Marcello Ercole

Produced by Ercole / Ricci
Music by Ryan Taubert

Namibia, a suggestive country. Eroded cliffs by the wind, very deep canyons, boundless deserts, the cold ocean and wild animals makes Namibia an inhospitable and sublime land. A fragile ecosystem that we must preserve.

Website

Namibia officially the Republic of Namibia, is a country in Southern Africa. Its western border is the Atlantic Ocean; it shares land borders with Zambia and Angola to the north, Botswana to the east and South Africa to the south and east. Although it does not border Zimbabwe, less than 200 metres of the Zambezi River separates the two countries. Namibia gained independence from South Africa on 21 March 1990, following the Namibian War of Independence. Its capital and largest city is Windhoek, and it is a member state of the United Nations (UN), the Southern African Development Community (SADC), the African Union (AU), and the Commonwealth of Nations.

Namibia, the driest country in Sub-Saharan Africa, was inhabited since early times by the San, Damara and Nama people. Around the 14th century, immigrating Bantu peoples arrived as part of the Bantu expansion. Since then, the Bantu groups, the largest being the Ovambo, have dominated the population of the country; since the late 19th century, they have constituted a majority.

From Wikipedia

Politics: Bernie Sanders “Medicare For All” (NPR)

NPR PodcastsAs we head into South Carolina’s primary and gear up for Super Tuesday, the 2020 candidates are looking to stand out to voters. But perhaps no policy proposal has marked this election more than Sen. Bernie Sanders’s push for Medicare for All.

While the Democratic candidates agree on expanding health coverage, they’re divided on how to insure everyone, whether to insure everyone, and, of course, how to pay for it all.

Bernie Sanders Website

So how are they similar? How are they different? And how does that compare to President Trump?

Rachana Pradhan, correspondent for Kaiser Health NewsNoam Levey, national healthcare reporter for The LA Times; and Dan Diamond, health reporter for Politico and host of the “Pulse Check” podcast helped us break down where each candidate stood on health care.

Heart Health: “Statins” Are Beneficial Only With Healthy Diets & Lifestyle

Taking a statin helps keep your cholesterol levels in check. How can that be?

Mayo Clinic LogoDr. Stephen Kopecky explains that some people ask to be put on a statin. That’s because statins, while important and effective, are just one part of the whole heart-healthy picture. When you combine a statin with regular exercise, maintaining a healthy weight, controlling stress, not smoking and eating foods based on the Mediterranean diet, you can improve your heart health.

Dr. Kopecky says if you work in lifestyle changes slowly over time, you’ll be on your way to better heart health.

Statins are drugs that can lower your cholesterol. They work by blocking a substance your body needs to make cholesterol. Statins may also help your body reabsorb cholesterol that has built up in plaques on your artery walls, preventing further blockage in your blood vessels and heart attacks.

Several statins are available for use in the United States. They include:

  • atorvastatin (Lipitor)
  • lovastatin (Altoprev)
  • pitavastatin (Livalo)
  • pravastatin (Pravachol)
  • rosuvastatin (Crestor)
  • simvastatin (Zocor)

Sometimes, a statin is combined with another heart health medication. Examples are atorvastatin/amlodipine (Caduet) and simvastatin/ezetimibe (Vytorin).

Increasing evidence suggests that statins do more than just lower bad cholesterol. Research has found that the medicines can safely prevent heart disease in certain adults ages 40 to 75. But the benefits aren’t entirely clear for the elderly. And doctors still want to know more about the side effects of statins.

Inteviews: 67-Year Old British Author Hilary Mantel – “Extraordinarily Probable Fiction” (NYT)

Excerpts from a New York Times interview (Feb 24, 2020):

Hilary Mantel by Ellie Smith for the New York Times
“All that time I was listening to the past, and now I’m almost talking for a living,” Mantel said, “and it feels very frivolous and empty compared to the stillness that there used to be in every day.”Credit…Ellie Smith for The New York Times

“Hilary has reset the historical patterns through the way in which she’s reimagined the man,” said Diarmaid MacCulloch, an Oxford theology professor who published a new Cromwell biography in 2018. “It’s fiction which is extraordinarily probable, and it’s remarkably like the Cromwell I’d been excavating myself.”

Hilary Mantel has a recurring anxiety dream that takes place in a library. She finds a book with some scrap of historical information she’s been seeking, but when she tries to read it, the words disintegrate before her eyes.

“And then when you wake up,” she said, “you’ve got the rhythm of a sentence in your head, but you don’t know what the sentence was.”

To an unusual degree for a novelist, Mantel feels bound by facts. That approach has made her latest project — a nearly 1,800-page trilogy about the 16th-century lawyer and fixer Thomas Cromwell — more complicated than anything she’s undertaken in her four decades of writing.

Read full interview article

New Video Travel Guides: Where To Go In “Vienna”

Our Vienna Travel Guide! So many layers to this wonderful Austrian city and we barely had time to scratch the surface. Vienna is one of those cities that offers something for everyone; culture, food, adventure.

Vienna is polished on the surface but dig a little deeper and there’s so much more to discover. Beyond the incredible museums, cathedrals, and markets, this Austrian city is an exciting year-round destination for all travelers.

Website

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