Professor Ashani Weeraratna has been studying the cancer microenvironment in her lab for the past 17 years. Taking into account that the tissues in our bodies change as we age is important when researching cancer biology. She hopes that gaining a better understanding of how the growth of cancer cells is affected by their direct cellular ‘neighbourhood’, especially when we age, could be key to developing better treatments for patients with cancer. Read more in https://www.nature.com/immersive/d428…
Vaccines are medicines that train the body to defend itself against future disease, and they have been saving human lives for hundreds of years. Vaccines are medicines that train the body to defend itself against future disease.
Hypertrophic cardiomyopathy is a thickening of the heart muscle, making it more difficult to pump blood. Dr. Steve Ommen is a Mayo Clinic cardiologist who specializes in the disease. He says shortness of breath or chest pain, especially during exercise, are common symptoms. Many people with the disease won’t have any significant health problems. But there are cases that require treatment. If a patient has symptoms that affect quality of life, the disease is treated with medications. Surgery or other procedures also may be necessary in some cases.
The rollout of the Johnson & Johnson vaccine has been paused in the US, Europe and South Africa after reports of rare blood clotting in a very small number of people. Health authorities said they were halting the use of the shot while they investigate the cases — and that they were doing this out of “an abundance of caution.” The Astra Zeneca jab was also recently temporarily suspended in some countries after being linked to rare blood clots. Authorities are calling it a short “pause.” The US’s Johnson and Johnson vaccine has hit the same stumbling block as the UK’s AstraZeneca jab did last month: a likely link to a rare and deadly blood clot. Use of Johnson and Johnson’s Janssen vaccine has now been halted across the US, Europe and South Africa, with health authorities investigating six incidents of clotting in younger women, one of them fatal. The US-developed vaccine uses an adenovirus to trigger immunity – the same mechanism as the UK’s AstraZeneca vaccine. It accounts for roughly 5 percent of vaccines delivered so far in the US. This is a setback to Europe, too. Johnson and Johnson announced it will delay it’s rollout on the continent. The company had already started processing an order from the EU of 200 million doses. The Janssen jab has been partially rolled out in Africa, where a majority of countries don’t have enough vaccines even for their healthcare workers. The African Union signed a deal for 220 million doses this year. But US authorities remain hopeful. They’re saying it could only be a matter of days before the rollout resumes.
Remember the first COVID-19 vaccine jabs? They gave us hope that life might return to what it was before the pandemic. If we could only get enough people vaccinated. But some of the nations leading the world in vaccinations are still struggling with the coronavirus.
The advent of commercial genome sequencing has recently, and credibly, been compared to the invention of the microscope, a claim that led me to wonder whether this new, still relatively obscure technology, humming away in well-equipped labs around the world, would prove to be the most important innovation of the 21st century.
And unexpectedly, Covid-19 has proved to be the catalyst. “What the pandemic has done is accelerate the adoption of genomics into infectious disease by several years,” says deSouza, the Illumina chief executive. He also told me he believes that the pandemic has accelerated the adoption of genomics into society more broadly — suggesting that quietly, in the midst of chaos and a global catastrophe, the age of cheap, rapid sequencing has arrived.
Satchin Panda is a professor in Salk’s Regulatory Biology Laboratory. He explores the genes, molecules and cells that keep the whole body on the same biological clock, also known as a circadian rhythm. On this episode of Where Cures Begin, Panda talks about what a biological clock is, how living in sync with your clock can improve your health, and how growing up in India informed his research.
Vaccine science and technology is advancing. Next generation vaccines could change how we combat infectious diseases, and it’s important to understand how the technology works.