From Phys.org online article:
“As a result, today’s epidemic of physical inactivity in conjunction with highly processed, high-sodium diets contributes to thicker, stiffer hearts that compromise the heart’s ability to cope with endurance physical activity, and importantly this may start to occur prior to increases in resting blood pressure,” explains Shave.
The landmark study analyzed 160 humans, 43 chimpanzees and five gorillas to gain an understanding of how the heart responds to different types of physical activity. In collaboration with Harvard University’s Daniel Lieberman and Aaron Baggish, UBC Professor Robert Shave and colleagues compared left ventricle structure and function in chimpanzees and a variety of people, including some who were sedentary but disease-free, highly active Native American subsistence farmers, resistance-trained football linemen and endurance-trained long-distance runners.
To read more: https://phys.org/news/2019-09-evolution-heart.html
From an InterestingEngineering.com online article:
“We are extremely proud of what we have accomplished, from the ability to 3D bioprint human cardiac tissue last summer to a mini heart with full structure now. These milestones are a testament to the hard work of our team and the proprietary process we have developed that enables this type of scientific achievement,” said Birla in a press release. “We believe we are at the forefront of whole heart bioengineering, a field that has matured quickly over the last year, and well-positioned to continue our rapid scientific advancement.”
BIOLIFE4D, the biotech company based out of Chicago, announced it has successfully demonstrated the ability to 3D bioprint a mini human heart, a big step in someday printing out a full-sized human heart that can be used for a transplant.
To read more: https://interestingengineering.com/a-company-creates-the-first-3d-printed-mini-heart?_source=newsletter&_campaign=EVmJjW5YyX1pq&_uid=46dBBxnxd7&_h=0c209d493fa27bb2c39469a873cbbd733289c833&utm_source=newsletter&utm_medium=mailing&utm_campaign=Newsletter-10-09-2019
From a ScienceDaily.com online release:
Physical inactivity, smoking, high blood pressure, diabetes, and high cholesterol play a greater role than genetics in many young patients with heart disease, according to research presented today at ESC Congress 2019 together with the World Congress of Cardiology. The findings show that healthy behaviours should be a top priority for reducing heart disease even in those with a family history of early onset.
The study enrolled 1,075 patients under 50, of whom 555 had coronary artery disease (known as premature CAD). Specific conditions included stable angina, heart attack, and unstable angina. The average age was 45 and 87% were men. Risk factor levels and genetics in patients were compared to a control group of 520 healthy volunteers (average age 44, and 86% men). Patients and controls were recruited from the Genes in Madeira and Coronary Disease (GENEMACOR) database.
Five modifiable risk factors were assessed: physical inactivity, smoking, high blood pressure, diabetes, and high cholesterol. Nearly three-quarters (73%) of patients had at least three of these risk factors compared to 31% of controls. In both groups, the likelihood of developing CAD increased exponentially with each additional risk factor. The probability of CAD was 3, 7, and 24 times higher with 1, 2, and 3 or more risk factors, respectively.
To read more: https://www.sciencedaily.com/releases/2019/09/190902181602.htm
From a Circulation online release:
…these results indicate that sleep may play an important role in health disparities and may represent a modifiable risk factor (along with diet and physical activity) for cardiometabolic risk in general and cardiometabolic health disparities specifically.
Our review of the epidemiological data on the impact of sleep duration and disorders on cardiovascular health suggests the following:
Both short- and long-duration sleep and sleep disorders such as SDB and insomnia are associated with adverse cardiometabolic risk profiles and outcomes.
Sleep restriction has a negative impact on energy balance, but it is less clear whether treating sleep disorders has a positive impact on obesity risk.
Treating those with sleep disorders may provide clinical benefits, particularly for blood pressure.
Sleep is increasingly recognized as an important lifestyle contributor to health. However, this has not always been the case, and an increasing number of Americans choose to curtail sleep in favor of other social, leisure, or work-related activities. This has resulted in a decline in average sleep duration over time. Sleep duration, mostly short sleep, and sleep disorders have emerged as being related to adverse cardiometabolic risk, including obesity, hypertension, type 2 diabetes mellitus, and cardiovascular disease.
To read more click on the following link: https://www.ahajournals.org/doi/10.1161/CIR.0000000000000444
From a Harvard Medical School article:
Costochondritis is caused by inflammation of the cartilage between the ribs and the breastbone, called the costosternal joints (see illustration). This uncommon condition can trigger a stabbing, aching pain that’s often mistaken for a heart attack.
The main symptom of costochondritis is chest pain, which may be sharp or dull and gnawing. It tends to get worse when a person takes a deep breath or coughs, and the chest may feel tender and possibly swollen when pressed. In contrast, people in the throes of a heart attack often say they feel chest discomfort rather than chest tenderness, and they describe sensations such as squeezing, tightness, pressure, or feeling like an elephant is sitting on my chest.
“The development of these battery-free technologies will revolutionize implantable devices,” says Ramses Martinez, a researcher in industrial and biomedical engineering at Purdue University, who was not involved in either study. “Soon traditional rigid implants will evolve into conformable systems capable of harvesting the energy they need to function from the patient.”
Current pacemakers have batteries that last less than 10 year and require expensive surgery to replace them. Harini Barath (Scientific American, May 28, 2019) reports that the pig’s heart generated ample energy to power a human pacemaker. Read more below: