The Globalist (May 1, 2024): As war closes in on Darfur’s besieged capital, we get the latest on the conflict in Sudan.
Then: Japan, Australia, the US and the Philippines meet in Hawaii for defence talks, we hear the case for EU expansion and examine Georgia’s controversial foreign-agent bill. Plus: responsible tourism in Mallorca.
The Globalist (April 30, 2024): Egypt and Qatar flex their mediator muscles as a Hamas delegation arrives in Cairo for ceasefire talks, Greece pledges €2bn to build its own ‘Iron Dome’, Germany’s far-right is on trial and we hear about the continuation of Ukraine’s global relief programme despite the ongoing war.
Plus: newspapers, aviation news and Madonnamania takes over Brazil.
The Globalist (April 29, 2024): Hannah McCarthy joins us to discuss the latest from Gaza. Also in the programme: Tara O’Connor explores the IDA for Africa Heads of State Summit in Nairobi, where leaders are meeting to discuss the continent’s financing and security.
Also in the programme: we speak to Sebastian Conran, designer in residence at Habitat, as the company celebrates its 60th anniversary. Plus: a flick through the day’s papers.
The Globalist (April 26, 2024): Monocle’s Hannah Lucinda Smith on Mark Rutte’s visit to Istanbul to meet Recep Tayyip Erdogan as he seeks to woo support to become the next Nato chief.
Also in the programme: Ed Stocker sits down with Lufthansa CEO Jens Ritter as the airline prepares to launch its new premium cabins known as Allegris. Plus: we discuss why the Indian city of Bengaluru is offering incentives for those who head to the polls and the latest news in film.
‘Science Magazine – April 25, 2024: The new issue features ‘Born to Explore’ – Exploratory tendency leads to diversification; Can science address loneliness?; Vitamin D, microbiota, and cancer immunity; A safer version of a 140-year-old chemical reaction…
Vitamin D modulates intestinal epithelial cell function to enhance antitumor microbes
The gut microbiome has been shown to modulate the response of cancer patients to therapy, but precisely how microbiota affect anticancer immunity is still being elucidated. Giampazolias et al. report that vitamin D bioavailability in mice influences the composition of the gut microbiome (see the Perspective by Franco and McCoy). After dietary manipulation, vitamin D levels were observed to affect gut bacteria, which in turn improved cancer immunotherapy and antitumor immunity. In humans, low vitamin D levels were correlated with tumor development, and gene signatures of vitamin D activity were associated with improved patient responses to immunotherapy. These findings highlight the connection between vitamin D and the immune system through gut bacteria and may have applications for improving cancer therapies.
The power of curiosity
Lake Tanganyika contains one of the most impressive adaptive radiations, with about 250 species of cichlid occupying a variety of niches. Much research has focused on understanding the drivers of this and other adaptive radiations. Trembo et al. looked in depth at 57 of these cichlid species with regard to their behavior, ecomorphology, and genomics. They found that one behavior in particular, a tendency to explore, was related to niche adaptation, and they identified a regulatory gene that is highly associated with this behavior. These findings suggest the existence of an adaptive syndrome driven in part by a tendency to explore what is new.
The Globalist (April 25, 2024): We discuss the state of relations between the world’s two most powerful countries as US secretary of state Antony Blinken visits China.
Plus: the current humanitarian situation in Gaza, the UN warns that the crisis in Haiti is “catastrophic” and Spanish-language music sweeps global charts.
‘Nature Magazine – April 24, 2024: The latest issue cover features‘ Switching Channels’ – Organoids and assembloids offer model way to test potential therapy for Timothy syndrome…
The Globalist (April 24, 2024): As Nato’s secretary general, Jens Stoltenberg, and the UK prime minister, Rishi Sunak, visit Warsaw, we examine the role that Poland plays in the diplomatic field.
Then: Donald Trump’s criminal trial; Taiwan wants to remove statues of Chinese dictator Chiang Kai-shek; and an exploration of the future of ticket resale with the managing director of Viagogo. Plus: aviation news and a lost Klimt painting is auctioned.
The Globalist (April 23, 2024): Paul Rogers of OpenDemocracy explains why global defence expenditure is at its highest level since records began.
Elsewhere, Monocle’s Istanbul correspondent, Hannah Lucinda Smith, tells us about Recep Tayyip Erdogan’s visit to Iraq, the Maldives shifts its allegiance from India to China and we ask why the US is withdrawing troops from Niger. Plus: art and culture news.
News, Views and Reviews For The Intellectually Curious
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