Do you have good or bad microbiome? Or do you have the microbiome you deserve?
Gut Microbiome, the new Open Access journal from Cambridge University Press and The Nutrition Society has published its first papers, including the animated abstract above from the paper: Hill, C. (2020) “You have the microbiome you deserve,” Gut Microbiome, Cambridge University Press, 1, p. e3.
Access the paper here: https://bit.ly/3bFOjc7
According to a recent study, obesity increases the risk of dying of Covid-19 by nearly 50%. Governments around the world are now hoping to encourage their citizens to lose weight. But with so much complex and often contradictory diet advice, as well as endless food fads, it can be hard to know what healthy eating actually looks like.
How many pieces of fruit and vegetables should you eat a day? Will cutting out carbs help you lose weight? Is breakfast really the most important meal of the day? Speaking to Tim Spector, professor of genetic epidemiology at King’s College London about his new book Spoon-Fed, Madeleine Finlay asks why we’re still getting food science wrong, and explores the current scientific evidence on snacking, supplements and calorie labels.
Tim Spector is a Professor of Genetic Epidemiology and Director of the TwinsUK Registry at Kings College, London and has recently been elected to the prestigious Fellowship of the Academy of Medical Sciences. He trained originally in rheumatology and epidemiology. In 1992 he moved into genetic epidemiology and founded the UK Twins Registry, of 13,000 twins, which is the richest collection of genotypic and phenotypic information worldwide. He is past President of the International Society of Twin Studies, directs the European Twin Registry Consortium (Discotwin) and collaborates with over 120 centres worldwide. He has demonstrated the genetic basis of a wide range of common complex traits, many previously thought to be mainly due to ageing and environment. Through genetic association studies (GWAS), his group have found over 500 novel gene loci in over 50 disease areas. He has published over 800 research articles and is ranked as being in the top 1% of the world’s most cited scientists by Thomson-Reuters. He held a prestigious European Research Council senior investigator award in epigenetics and is a NIHR Senior Investigator. His current work focuses on omics and the microbiome and directs the crowdfunded British Gut microbiome project. Together with an international team of leading scientists including researchers from King’s College London, Massachusetts General Hospital, Tufts University, Stanford University and nutritional science company ZOE he is conducting the largest scientific nutrition research project, showing that individual responses to the same foods are unique, even between identical twins. You can find more on https://joinzoe.com/ He is a prolific writer with several popular science books and a regular blog, focusing on genetics, epigenetics and most recently microbiome and diet (The Diet Myth). He is in demand as a public speaker and features regularly in the media.
Does reducing salt improve our blood pressure?
There is consistent evidence that moderate reductions (i.e. a decrease of 3 to 5 g or ½ to 1 teaspoon a day) in salt intake can lead to a reduction in blood pressure.5,6 However, these effects may not be the same for everyone and will depend on an individual’s starting blood pressure (greater benefits are seen in those with higher blood pressure), their current level of salt intake, genetics, disease status and medication use.
It is important to note that salt is not the only lifestyle factor that can influence our blood pressure. Other factors such as eating enough potassium, maintaining a healthy body weight, not smoking, and being physically active are also important when it comes to reducing blood pressure. You can find 7 lifestyle tips to help reduce blood pressure here.
High salt foods:
- Processed meats such as bacon, salami, sausages and ham
- Gravy granules, stock cubes, yeast extracts
- Olives, pickles and other pickled foods
- Salted and dry-roasted nuts and crisps
- Salted and smoked meat and fish
- Sauces: soy sauce, ketchup, mayonnaise, BBQ sauce
What is salt?
Salt is the common name for sodium chloride (or NaCl). It consists of 40% sodium and 60% chloride. In other words, 2.5 g of salt contains 1 g of sodium and 1.5 g of chloride.
Why do we need salt?
Both sodium and chloride are essential for many body functions. They help regulate blood pressure, control fluid balance, maintain the right conditions for muscle and nerve function and allow for the absorption and transport of nutrients across cell membranes. Chloride is also used to produce stomach acid (hydrochloric acid, HCl) which helps us digest foods.
How much salt do we need per day?
The exact minimum daily requirement for salt is unknown, but it is thought to be around 1.25 g – 2.5 g (0.5 – 1 g sodium) per day.1 As salt is found in a large variety of foods the risk of deficiency is low.1,2 The European Food Safety Authority (EFSA) has stated that a salt intake of 5 g per day (equivalent to 2 g of sodium) is sufficient to meet both our sodium and chloride requirements as well as reduce our risk of high blood pressure and heart disease.1,2 This is equivalent to around 1 teaspoon of salt per day from all sources.
Both sodium and chloride are released from our body through our urine and when we sweat. This means bouts of heavy sweating such as during exercise can increase our salt requirements slightly. However, as most people consume well above required levels it is usually not necessary to increase salt intake during these conditions.1
Registered Dietitian and Certified Diabetes Educator Sherri Shafer discusses the importance of carbohydrates in the daily diet. Shafer then offers a plan for how much protein, fat and carbohydrate would be healthy in a day.
“The findings of this study are promising and reinforce what we’ve seen in other studies — fasting diets are a viable option for people who want to lose weight, especially for people who do not want to count calories or find other diets to be fatiguing,” Varady said.
…participants in both daily fasting groups reduced calorie intake by about 550 calories each day simply by adhering to the schedule and lost about 3% of their body weight. The researchers also found that insulin resistance and oxidative stress levels were reduced among participants in the study groups when compared with the control group.
Two daily fasting diets, also known as time-restricted feeding diets, are effective for weight loss, according to a new study published by researchers from the University of Illinois at Chicago.
The study reported results from a clinical trial that compared a 4-hour time-restricted feeding diet and a 6-hour time-restricted feeding diet to a control group.
“This is the first human clinical trial to compare the effects of two popular forms of time-restricted feeding on body weight and cardiometabolic risk factors,” said Krista Varady, professor of nutrition at the UIC College of Applied Health Sciences and corresponding author of the story.
We observed that increased adherence to the MedDiet modulates specific components of the gut microbiota that were associated with a reduction in risk of frailty, improved cognitive function and reduced inflammatory status.
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Paul O’Toole; who is Professor of Microbial Genomics, Head of School of Microbiology and Principal Investigator in APC Microbiome Ireland, an SFI funded centre at University College Cork, Ireland, on “Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across 5 European countries” published in paper copy in Gut in July 2020.
Obesity is at the root of silent epidemics such as type 2 diabetes and nonalcoholic fatty liver disease.
Laura Schmidt explores the causes and solutions, taking lessons from tobacco: reducing the availability of harmful substances reduces consumption, thereby reducing harms to health. She talks about the UCSF Healthy Beverage Initiative and the effects it has had on employee health.
Recorded on 02/13/2020. [5/2020] [Show ID: 35586]
From a BMJ Study article (April, 2020):
Compared with usual diet, moderate certainty evidence supports modest weight loss and substantial reductions in systolic and diastolic blood pressure for low carbohydrate (eg, Atkins, Zone), low fat (eg, Ornish), and moderate macronutrient (eg, DASH, Mediterranean) diets at six but not 12 months. Differences between diets are, however, generally trivial to small, implying that people can choose the diet they prefer from among many of the available diets (fig 6) without concern about the magnitude of benefits.
The worldwide prevalence of obesity nearly tripled between 1975 and 2018.1 In response, authorities have made dietary recommendations for weight management and cardiovascular risk reduction.23 Diet programmes—some focusing on carbohydrate reduction and others on fat reduction—have been promoted widely by the media and have generated intense debates about their relative merit. Millions of people are trying to lose weight by changing their diet. Thus establishing the effect of dietary macronutrient patterns (carbohydrate reduction v fat reduction v moderate macronutrients) and popular named dietary programmes is important.
Biological and physiological mechanisms have been proposed to explain why some dietary macronutrient patterns and popular dietary programmes should be better than others. A previous network meta-analysis, however, suggested that differences in weight loss between dietary patterns and individual popular named dietary programmes are small and unlikely to be important.4 No systematic review and network meta-analysis has examined the comparative effectiveness of popular dietary programmes for reducing risk factors for cardiovascular disease, an area of continuing controversy.