Tag Archives: UK

Study: “Probiotic Drink” Developed That Thwarts Antibiotic Resistance

From a Genetic Engineering & Biotechnology News online article:

Genetic Engineering & Biotechnology News logo“We were able to show that if you can stop the plasmid from replicating, then most of the bacteria lose the plasmid as the bacteria grow and divide. This means that infections that might otherwise be hard to control, even with the most powerful antibiotics available, are more likely to be treatable with standard antibiotics.”

journal.pone.0225202.g001
Fig 1. Anticipated exploitation of pCURE as a probiotic treatment for at-risk individuals. Before treatment, plasmids carrying antibiotic resistance genes are shown as purple circles. After treatment, target plasmids are replaced by pCURE (green circle) which could be engineered to later “self-destruct”. Note that not all gut bacteria carry resistance plasmids but pCURE can enter all Enterobacteriaceae as well as other bacteria. Reduced resistance levels in the gut decrease the chance of treatment failure when infections elsewhere in the body (eg lungs or urinary tract) arise from gut bacteria.

 

Researchers headed by a team at the University of Birmingham in the U.K. have developed a probiotic drink containing genetic elements that are designed to thwart antimicrobial resistance (AMR) in gut bacteria at the genetic level. The drink targets small DNA elements called plasmids that carry antibiotic resistance genes, and which are able to replicate independently and spread between bacteria. By preventing these plasmids from replicating, the antibiotic resistance genes are displaced, effectively resensitizing the bacteria to antibiotics.

Read more

Air Travel: Electric Planes From “Eviation” Could Be Flying In UK In 2 Years

Electric planes could soon fly commuters from city to city, a transport minister has disclosed. George Freeman, minister for transport and innovation, told The Telegraph’s “Chopper’s Brexit Podcast” that there was “a whole opportunity for short-haul transport at low altitude” that the country was yet to grasp.

Eviation Electric Aircraft Alice

In an episode of 2020 predictions, Mr Freeman said: “This will be the year where we begin to see a whole new world of low level aviation, Velocopters, electric planes. We already run the world’s first commercial electric plane service and Boris and I have been looking at how we can develop UK leadership in electric plane technology.” Mr Freeman said the planes could take eight passengers and fly at 2,500ft and could be used for “short hops between cities that take you an hour or two in the car, pumping out carbon monoxide.”

“At the moment the electric plane seats eight. But you know what the aerospace industry is like – eight soon becomes 18, and that soon becomes 28. We are determined to lead in the revolution of clean transport.”

To listen to the podcast in full, head here: https://www.telegraph.co.uk/politics/…

Classic Car Books: “Healey – The Men & The Machines”

Healey The Men & The Machines John Nikas January 2020“Nikas combines extensive research into a previously unavailable and highly detailed archive of Donald Healey’s personal records with the author’s masterful ability to weave together an amazing level of detail while making it an eminently readable story. The result is a book that both seasoned automotive historians and anyone with an interest in the story of a life well lived will enjoy. Until you’ve read this book, you don’t know the true story of Donald Healey and his cars”
(Reid Trummel, Editor in Chief, Healey Marque)

Written in collaboration with Gerry Coker, the designer responsible for the iconic Austin-Healey 100 and Sprite, this volume represents the most complete account ever of the sports cars built at Warwick, Longbridge, Abingdon and West Bromwich. With unprecedented access to Donald and Geoffrey Healey’s private papers, diaries, scrapbooks and photo albums, corporate and financial records from BMC, Donald Healey Motor Company and Healey Automobile Consultants, the files of Jensen Motors and Nash-Kelvinator, dozens of personal interviews and exhaustive research into previously unavailable primary source material, this book provides a thorough account of the true story behind these automobiles and the individuals who created them.

To read more and/or purchase

Best Design & Food: “KILN” Thai Restaurant, London (Dan Preston LTD)

From a Spectator Life online article:

KILN Soho London Thai Restaurant Designed by Dan Preston LTDWith just four tables, a few counter seats and no reservations, getting a spot at Kiln can be a challenge. But it is one that is absolutely worth the wait.

Chosen as the UK’s Best Restaurant in the 2018 National Restaurant Awards, this Soho hotspot specialises in a roadside barbeque style of Thai cooking. The kiln it is named after is the hulking stove which dominates the restaurant. On it sits countless rustic claypots from which wafts a tempting mix of palm sugar, sweet basil and hot charcoal.The 22 seats along the steel counter are the best in the house, as you can watch the chefs scrupulously chopping, flipping and searing ingredients – most of which have been picked or caught just a few hours before.

Dan Preston LTD Design Studio London
http://www.danpreston.co.uk/

At less than £7, the baked glass noodles with Tamworth pork belly and brown crab meat is probably the best value dish in London.

To read more: https://life.spectator.co.uk/articles/the-five-best-thai-restaurants-in-london/

Politics: “Baby Boomers Versus Millennials” Battle Brewing In Great Britain

From a The Atlantic online article:

Willetts had stumbled onto one of the great divides of modern politics: young versus old. In Britain, age is now a better predictor of voting intention than social class. Overall, the Boomers voted for Brexit in 2016 and the Conservatives in 2017; their Millennial children voted Remain and Labour. The single biggest error that Theresa May, the prime minister in the lead-up to the 2017 election, made during that process was to float the idea that older people might have to contribute more to the spiraling costs of their own retirement care. The “dementia tax” prompted an immediate, ferocious response, and May backed down.

 

That is not an isolated example. A guiding principle of politics in Britain, and elsewhere in the West, is: What Boomers want, Boomers get. Working-age benefits, for example, have been frozen since the 2015 budget, but the state pension has consistently risen. (At this election, Britain’s two main parties have both promised to keep increasing pensions; Jeremy Corbyn’s Labour has also pledged £58 billion ($74.7 billion) to Boomer women affected by the rise in the female state pension age from 60 to 66.

generation-pinched-book-launch-for-the-second-edition-of-the-pinch-5-1024

 

The debate is also about so much more than abstract disagreements over policy and government funding. Caring for the elderly, for example, becomes wrapped up in assertions of “just deserts”—I’ve worked hard all my life and paid my taxes—and fears about money-grubbing children selling off their parents’ houses. It is also, like taxes on inheritance, a subject that prods at many people’s deep desire to pass something on to their offspring.

To read more: https://www.theatlantic.com/international/archive/2019/11/britain-election-boomers/602680/

Nostalgia: “1961 Jaguar E-Type SI ‘CUT-7′” Champion Race Car (Classic Driver)

From a Classic Driver online article:

‘CUT 7’ was campaigned extensively throughout the 1962 season. With victories at Mallory Park, Silverstone, Crystal Palace and Snetterton, Protheroe had his eyes set on securing the Autosport National Championship for Production Sports Cars, and with just one retirement in 10 outings, he won the Over 3-litre class.

 

Former RAF pilot Dick Protheroe was no stranger to the Jaguar brand. Stationed in Egypt in 1952, Protheroe acquired his first Jaguar, an aluminium bodied XK120 which he modified and campaigned before returning to England in 1953.

1961 Jaguar E-Type SI 'CUT-7' front

Chassis Number ‘860004’, was the fourth right-hand drive fixed-head E-type produced by Jaguar at the famous Brown’s Lane factory in Coventry. Painted in Opalescent Gunmetal Grey with dark blue interior trim, it was aptly delivered to Protheroe on 13thSeptember 1961 by Jaguar Dealer, Sturgess of Leicester. Robin Sturgess had a close affinity to the marque having raced XK’s, C-type, D-type and E-types successfully for many years.

To read more: https://www.classicdriver.com/en/car/jaguar/e-type-si/1961/716497