From a PLOS Medicine online study:
Depression is associated with increased odds of dementia, even more than 20 years after diagnosis of depression, and the association remains after adjustment for familial factors. Further research is needed to investigate whether successful prevention and treatment of depression decrease the risk of dementia.
The risk of dementia is increased for decades after a diagnosis of depression, where those diagnosed with especially severe depressions are at increased risk.

Dementia is common among the elderly, causing severe individual suffering as well as societal strain. As the proportion of people aged 65 years and above is rapidly increasing in the world population, the number of individuals with dementia is expected to double within 20 years, and this condition was estimated to have a worldwide cost of US$604 billion in 2010. Effective treatments for dementia remain scarce; however, a preventive approach may be possible through the identification of high-risk individuals and potentially modifiable risk factors.
“Amyloid is important in initiating disease, but the actual damage in the brain is probably due to the accumulation of tau,” Holtzman told MedPage Today. “Normally, tau protein is inside cells, but there is more and more evidence suggesting that its spread to different parts of the brain is responsible for the progression of Alzheimer’s disease.”
“Our data showed that rates of accelerating blood pressure elevation were significantly higher in women than men, starting earlier in life,” said Cheng, the Erika J. Glazer Chair in Women’s Cardiovascular Health, who also serves as director of Cardiovascular Population Sciences at the Barbra Streisand Women’s Heart Center. “This means that if we define the hypertension threshold the exact same way, a 30-year old woman with high blood pressure is probably at higher risk for cardiovascular disease than a man with high blood pressure at the same age.”







Becoming an Age-Friendly Health System entails reliably acting on a set of four evidence-based elements of high-quality care and services, known as the “4Ms,” for all older adults. When implemented together, the 4Ms represent a broad shift to focus on the needs of older adults:
Among older adults age 50–80, 43% had ever reviewed doctor ratings; 14% had reviewed ratings more than once in the past year, 19% had done so once in the past year, and 10% had reviewed ratings more than one year ago.
Ratings and reviews for nearly everything can be found online these days, including doctors. How are older adults using these ratings in their decisions about choosing doctors? In May 2019, the University of Michigan National Poll on Healthy Aging asked a
The book follows the journey of a writer in search of wisdom, as he encounters twelve distinguished American men over 80 — including Paul Volcker, the former head of the Federal Reserve, and Denton Cooley, the world’s most famous heart surgeon. In these and other intimate conversations, the book explores and honors the particular way that each man faces four challenges of living a good old age: Am I still a man? Do I still matter? What is the meaning of my life? Am I loved?