Heart Disease: Stents, Bypass Surgery Provide No Benefits To Stable Patients In Large Funded Trial

From a Stanford Medicine online release:

Stent in Coronary Artery“For patients with severe but stable heart disease who don’t want to undergo these invasive procedures, these results are very reassuring,” said David Maron, MD, clinical professor of medicine and director of preventive cardiology at the Stanford School of Medicine, and co-chair of the trial, called ISCHEMIA, for International Study of Comparative Health Effectiveness with Medical and Invasive Approaches. 

“The results don’t suggest they should undergo procedures in order to prevent cardiac events,” added Maron, who is also chief of the Stanford Prevention Research Center.

Patients with severe but stable heart disease who are treated with medications and lifestyle advice alone are no more at risk of a heart attack or death than those who undergo invasive surgical procedures, according to a large, federally-funded clinical trial led by researchers at the Stanford School of Medicine and New York University’s medical school.

The trial did show, however, that among patients with coronary artery disease who also had symptoms of angina — chest pain caused by restricted blood flow to the heart — treatment with invasive procedures, such as stents or bypass surgery, was more effective at relieving symptoms and improving quality of life.

To read more: http://med.stanford.edu/news/all-news/2019/11/invasive-heart-treatments-not-always-needed.html

Top New Travel Videos: “Vancouver Crossing” Directed By Wilkim Tan

Filmed, Edited and Directed by: Wilkim Tan

Vancouver Crossing is a short travel film that sends you on a journey of discovery as you cross through and experience Vancouver’s many unique aspects.

Vancouver Crossing Travel Video by Wilkim Tan 2019

From the beautiful trails of North Vancouver to North America’s largest food market in Richmond, Vancouver Crossing intertwines them together to show the contrast between Vancouver’s bustling urban landscape and it’s scenic nature hikes.

Credits:
Song: “Bloodflow” by Grandbrothers

Vancouver Crossing Travel Video by Wilkim Tan 2019

Website: https://vimeo.com/wilkimtan

Book Review Podcasts: Nicholas Buccola (“The Fire Is Upon Us”) Discusses A Great Intellectual Debate In 1965 (NY Times)

The Fire Is Upon Us Nicholas BuccolaIn 1965, James Baldwin, by then internationally famous, faced off against William F. Buckley Jr., one of the leading voices of American conservatism, in a debate hosted by the Cambridge Union in England. The debate proposition before the house was: “The American dream is at the expense of the American Negro.”

Nicholas Buccola’s “The Fire Is Upon Us” tells the story of that intellectual prizefight as well as the larger story of Buckley’s and Baldwin’s lives.

 

Retirement Planning: Nobel Prize Economist William Sharpe Offers Free E-Book For Retirees

Feom a Barron’s online interview article:

William Sharpe Nobel Prize Winning EconomistRight now, you tend to have investment advisors for retirees, and insurance advisors or salespersons for retirees, and it’s fairly rare to go to somebody who can sell you annuities or invest your money and has no financial incentive to tilt one way or the other. Ultimately, what I’d like to see are people who have knowledge of both annuities and investments, and who are compensated in a way that doesn’t influence the decision.

The idea is that you segment your money. It’s similar to using “buckets” but with a time component. A retiree might have a box for 2020 and a box for 2021, and 2022, etc.

Retirement Income Analysis by William SharpeNobel Prize–winning economist William Sharpe has spent most of his career thinking about risk. He’s behind the Capital Asset Pricing Model for gauging systemic risk and the eponymous Sharpe ratio, which captures risk-adjusted return.

A few decades ago, Sharpe turned his attention to what may be the biggest risk of all for most Americans—running out of money in retirement. The professor of finance, emeritus, at Stanford University’s Graduate School of Business created a computer program that eventually covered 100,000 retirement-income scenarios based on different combinations of life spans and investment returns for a retired couple. Sharpe has made this program available in a free ebook, Retirement Income Scenario Matrices.

To read more: https://www.barrons.com/articles/william-sharpe-how-to-secure-lasting-retirement-income-51573837934

Top Political Podcasts: Mark Shields And David Brooks On The Latest In Washington (PBS)

Shields and Brooks Political podcast Nov 15 2019Syndicated columnist Mark Shields and New York Times columnist David Brooks join Judy Woodruff to discuss the week in politics, including whether public impeachment hearings are making President Trump more or less vulnerable, what stood out about the witnesses who testified so far, whether Trump’s Ukraine dealings are surprising or “in character” and the latest dynamics among 2020 Democrats.

Museum Events: The Huntington Library Builds Centennial Float For 2020 Rose Parade (Timelapse Video)

For the first time in 50 years, The Huntington will join Pasadena’s world-famous Rose Parade® with a spectacular float, themed “Cultivating Curiosity,” to capture the spirit of The Huntington’s Centennial Celebration and highlight the institution’s rare research materials, inspiring art collections, and enchanting botanical gardens that have made it a beloved destination that welcomes 750,000 visitors each year.

Website: https://www.huntington.org/centennial

Technology Innovations: “WI-CHARGE” Charges Smart Devices Wirelessly With Infrared Light

From an Interesting Engineering online review:

Wi-Charge TechnologyWi-Charge says it has a solution to the problem. Its technology allows users to power small devices, such as smartphones, smart fire alarms, and smart locks, from several feet away without any wires.

The technology works by sending out a thin beam of infrared light. A receiver on the enabled device then converts the beam into electricity.

Electronic waste is expected to exceed 50 million tonnes by 2020. That number simply isn’t sustainable.

One company is aiming to get rid of one of the main culprits in e-waste: the electronic cable. Wi-Charge has created a method for powering devices wirelessly using safe and efficient infrared technology.

Aside from having the potential to end a great deal of waste, the company is also aiming to meet a growing demand for power that will only increase with the advent of 5G.

WiCharge_Charging_-infographic_wide_v2

To read more: https://interestingengineering.com/is-wireless-power-the-future-for-charging-smart-home-devices?_source=newsletter&_campaign=YqN5dY3r3bJLA&_uid=46dBBxnxd7&_h=0c209d493fa27bb2c39469a873cbbd733289c833&utm_source=newsletter&utm_medium=mailing&utm_campaign=Newsletter-15-11-2019

 

Health Reports: CDC Finds That 35,000 Americans Die Of Antibiotic-Resistant Infections Each Year

CDC Antibiotic Resistance Threats in the United States 2019More than 2.8 million antibiotic-resistant infections occur in the United States each year, and more than 35,000 people die as a result. In addition, nearly 223,900 people in the United States required hospital care for C. difficile and at least 12,800 people died in 2017.

Germs continue to spread and develop new types of resistance, and progress may be undermined by some community-associated infections that are on the rise. More action is needed to address antibiotic resistance. While the development of new treatments is one of these key actions, such investments must be coupled with dedicated efforts toward preventing infections in the first place, slowing the development of resistance through better antibiotic use, and stopping the spread of resistance when it does develop to protect American lives now and in the future.

CDC’s Antibiotic Resistance Threats in the United States, 2019 (2019 AR Threats Report) includes updated national death and infection estimates that underscore the continued threat of antibiotic resistance in the United States. New CDC data show that while the burden of antibiotic-resistance threats in the United States was greater than initially understood, deaths are decreasing since the 2013 report. This suggests that U.S. efforts—preventing infections, stopping spread of bacteria and fungi, and improving use of antibiotics in humans, animals, and the environment—are working, especially in hospitals. Vaccination, where possible, has also shown to be an effective tool of preventing infections, including those that can be resistant, in the community.

To read the report: https://www.cdc.gov/drugresistance/pdf/threats-report/2019-ar-threats-report-508.pdf

Food & Wine Review: Colorado Wine Regions Expand Amidst Challenges For Vineyards At Highest Elevations In The World

Colorado Wine CountryVineyards in Colorado are mostly nestled in the temperate, high elevation river valleys and mesas of Mesa and Delta counties, with some acreage in Montezuma county. Colorado’s grape growing regions range in elevation from 4,000 to 7,000 feet and are thus among the highest vineyards in the world, resulting in hot days accompanied by cool nights.

Grand Valley AVA wines in Colorado

The ‘continental climate’ in these regions create day to night temperature variations topically ranging from 25 to 30 degrees during the grape maturation months of August and September. The long warm daylight hours of intense high-altitude sunlight mature the fruit completely and build the natural sugars. The cool evenings cause the grapes to retain the acids so vital to premium winemaking. However, the high altitude can also present a challenge to grape growers, in that the average frost free growing season ranges from 150 to 182 days.

Website: https://coloradowine.com/the-tradition/

AMERICA THE BOUNTIFUL Regions once considered wine deserts are producing in-demand bottles as a new wave of winemakers boldly redraw the map of American wine regions. ILLUSTRATION BETH HOECKEL
AMERICA THE BOUNTIFUL Regions once considered wine deserts are producing in-demand bottles as a new wave of winemakers boldly redraw the map of American wine regions. ILLUSTRATION: BETH HOECKEL

Read Wall Street Jouranl article on young winemakers: https://www.wsj.com/articles/the-wines-to-buy-this-thanksgiving-a-guide-to-americas-up-and-coming-regions-11573836307

 

Podcasts: “Intitute For Clinical And Economic Review” (ICER) Is Helping To Lower Drug Prices (WSJ)

Wall Street Journal PodcastsAn obscure think tank in Boston is getting drug companies to lower their prices – using something called a QALY. WSJ’s Denise Roland explains what a QALY is, and why it’s controversial.

News, Views and Reviews For The Intellectually Curious