From a Stanford Medicine online release:
“For patients with severe but stable heart disease who don’t want to undergo these invasive procedures, these results are very reassuring,” said David Maron, MD, clinical professor of medicine and director of preventive cardiology at the Stanford School of Medicine, and co-chair of the trial, called ISCHEMIA, for International Study of Comparative Health Effectiveness with Medical and Invasive Approaches.
“The results don’t suggest they should undergo procedures in order to prevent cardiac events,” added Maron, who is also chief of the Stanford Prevention Research Center.
Patients with severe but stable heart disease who are treated with medications and lifestyle advice alone are no more at risk of a heart attack or death than those who undergo invasive surgical procedures, according to a large, federally-funded clinical trial led by researchers at the Stanford School of Medicine and New York University’s medical school.
The trial did show, however, that among patients with coronary artery disease who also had symptoms of angina — chest pain caused by restricted blood flow to the heart — treatment with invasive procedures, such as stents or bypass surgery, was more effective at relieving symptoms and improving quality of life.
To read more: http://med.stanford.edu/news/all-news/2019/11/invasive-heart-treatments-not-always-needed.html
More than 2.8 million antibiotic-resistant infections occur in the United States each year, and more than 35,000 people die as a result. In addition, nearly 223,900 people in the United States required hospital care for C. difficile and at least 12,800 people died in 2017.
“Senior citizens today are healthier, more engaged, and working longer than past generations,” says Chamberlain. “A ‘gray wave’ of senior citizens will be impacting the workforce in coming years, both in the United States and the United Kingdom.”
Notably 6 in 10 adults worldwide (59%) say they prefer to eat many small meals throughout the day, as opposed to a few larger ones, with younger consumers especially leaning into snacks over meals as that number rises to 7 in 10 among Millennials (70%).
“But what’s really intriguing is that we can now see how vitamin D might help the immune system fight cancer. We know when the Wnt/beta-catenin pathway is active in melanoma, it can dampen down the immune response causing fewer immune cells to reach the inside of the tumor, where they could potentially fight the cancer better.
“This study identifies a new molecular connection between exercise and inflammation that takes place in the bone marrow and highlights a previously unappreciated role of leptin in exercise-mediated cardiovascular protection,” said Michelle Olive, program officer at the National Heart, Lung, and Blood Institute Division of Cardiovascular Sciences. “This work adds a new piece to the puzzle of how sedentary lifestyles affect cardiovascular health and underscores the importance of following physical-activity guidelines.”
There was a massive shift in Roman residents’ ancestry, the researchers found, but that ancestry came primarily from the Eastern Mediterranean and Near East, possibly because of denser populations there relative to the Roman Empire’s western reaches in Europe and Africa.
The investigators discovered that patients with a higher genetic risk for depression were more likely to be diagnosed with depression over the next 2 years. However, more physically active patients at baseline were less likely to depression, even after they accounted for genetic risks.
When people are awake during the night, their behaviors are often mismatched with their internal body clocks. This can lead to nighttime eating, which can influence the way the body processes sugar and could lead to a higher risk in diabetes. “What happens when food is eaten when you normally should be fasting?” Scheer asked the audience. “What happens is that your glucose tolerance goes out the window….So your glucose levels after a meal are much higher.” This can increase people’s risk for diabetes.
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