Tag Archives: Physical Exercise

Study: “Intensive Diet And Exercise” Reverses Type 2 Diabetes In 61% Of Patients

From The Lancet Diabetes & Endocrinology (June 2020):

Our findings show that the intensive lifestyle intervention led to significant weight loss at 12 months, and was associated with diabetes remission in over 60% of participants and normoglycaemia in over 30% of participants. The provision of this lifestyle intervention could allow a large proportion of young individuals with early diabetes to achieve improvements in key cardiometabolic outcomes, with potential long-term benefits for health and wellbeing.

The Lancet Diabetes & Endocrinology

Type 2 diabetes is affecting people at an increasingly younger age, particularly in the Middle East and in north Africa. We aimed to assess whether an intensive lifestyle intervention would lead to significant weight loss and improved glycaemia in young individuals with early diabetes.
Between July 16, 2017, and Sept 30, 2018, we enrolled and randomly assigned 158 participants (n=79 in each group) to the study. 147 participants (70 in the intervention group and 77 in the control group) were included in the final intention-to-treat analysis population. Between baseline and 12 months, the mean bodyweight of participants in the intervention group reduced by 11·98 kg (95% CI 9·72 to 14·23) compared with 3·98 kg (2·78 to 5·18) in the control group (adjusted mean difference −6·08 kg [95% CI −8·37 to −3·79], p<0·0001). In the intervention group, 21% of participants achieved more than 15% weight loss between baseline and 12 months compared with 1% of participants in the control group (p<0·0001). Diabetes remission occurred in 61% of participants in the intervention group compared with 12% of those in the control group (odds ratio [OR] 12·03 [95% CI 5·17 to 28·03], p<0·0001). 33% of participants in the intervention group had normoglycaemia compared with 4% of participants in the control group (OR 12·07 [3·43 to 42·45], p<0·0001).

Health & Fitness: “What Is Exercise Physiology?” (Penn Medicine Video)

Exercise physiologists are healthcare professionals that work with patients who are deconditioned or have a variety of different health complications. They work with pulmonary and cardiac patients, as well as competitive athletes with a wide range of fitness issues.

Penn Medicine’s Christopher J. Kusmiesz, MS describes his role as “assessing a patient’s fitness level and providing recommendations and guidance so they can improve and reach their health and fitness goals.”

Exercise physiologists at Penn uses patient test results, recommendations from their cardiologist and the patient’s own goals to create an exercise program that is unique to each patient.


Exercise Health Benefits: “Should I Go To The Gym Today?” (MGH Video)

This presentation by Julia Browne, PhD, a clinical and research fellow in the Center of Excellence for Psychosocial and Systemic Research at Massachusetts General Hospital and Harvard Medical School was part of Schizophrenia Education Day 2019.

Health Studies: “Why Your Brain Needs Exercise” (Scientific American)

From a Scientic American online article:

Scientific American logoIn our own study of more than 7,000 middle-aged to older adults in the U.K., published in 2019 in Brain Imaging and Behavior, we demonstrated that people who spent more time engaged in moderate to vigorous physical activity had larger hippocampal volumes. Although it is not yet possible to say whether these effects in humans are related to neurogenesis or other forms of brain plasticity, such as increasing connections among existing neurons, together the results clearly indicate that exercise can benefit the brain’s hippocampus and its cognitive functions.

New Neurons in Aging Brains Why Your Brain Needs Exercise Scientific American December 18 2019

In fact, a growing body of research suggests that exercise that is cognitively stimulating may indeed benefit the brain more than exercise that does not make such cognitive demands. For example, Gerd Kempermann and his colleagues at the Center for Regenerative Therapies Dresden in Germany explored this possibility by comparing the growth and survival of new neurons in the mouse hippocampus after exercise alone or after exercise combined with access to a cognitively enriched environment. They found an additive effect: exercise alone was good for the hippocampus, but combining physical activity with cognitive demands in a stimulating environment was even better, leading to even more new neurons. Using the brain during and after exercise seemed to trigger enhanced neuron survival.

To read more: https://www.scientificamerican.com/article/why-your-brain-needs-exercise/

Exercise Studies: Older Adults’ “Fragmented Physical Exercise” Linked To Higher Death Rates

From a National Institute On Aging release:

Baltimore Longitudinal Study of Aging Studies
Baltimore Longitudinal Study of Aging Studies

Fragmented physical activity, but not total daily activity, was significantly associated with death, the researchers found. For each 10% higher degree of activity fragmentation, mortality risk was 49% greater. The duration of physical activity also mattered: Participants who frequently engaged in short bouts of activity of less than five minutes were more likely to die than those whose activity bouts lasted five minutes or longer. These associations held after adjusting for age, sex, body mass index and other factors.

Daily physical activity, which benefits health and quality of life, typically decreases in older adults. A new study shows that higher fragmentation of that activity — more transitions from activity to sedentariness — may be a better indicator of risk of death than a person’s overall level of physical activity.

Researchers from the Johns Hopkins Bloomberg School of Public Health, Baltimore, analyzed data from the NIA-supported Baltimore Longitudinal Study of Aging (BLSA), looking at a week’s worth of minute-by-minute physical activity for 548 healthy participants age 65 and older (average age, 76).

To read more: https://www.nia.nih.gov/news/fragmented-physical-activity-linked-higher-risk-death-older-adults

Chronic Pain: Cornell To Study Behavioral Change (Physical Exercise), Non-Drug Treatments For Pain

From a Cornell University news release:

Weill Cornell Medicine“Another behavior change is physical exercise,” Pillemer said. “A paradox of pain is that exercise helps reduce it, but it’s difficult for people in pain to think about exercising. So they don’t exercise, they get more sedentary and the pain increases; it’s a vicious circle. So how do you get people to actually change their behavior?”

More than 100 million Americans suffer from chronic pain – outnumbering those affected by heart disease, diabetes and cancer combined.

To develop innovative approaches to pain management, a team of behavioral and social science researchers on Cornell’s Ithaca campus, clinical researchers at Weill Cornell Medicine and computer scientists at Cornell Tech has received a five-year, $3 million grant from the National Institute on Aging, part of the National Institutes of Health (NIH).

To read more: http://news.cornell.edu/stories/2019/10/nih-grant-will-fund-non-pharmacological-pain-research