Inside the November 2022 Issue:
Research & review on #Alzheimers, global burden of benign prostatic hyperplasia, #WHO def of vitality capacity, IPD meta on social connection & #cognition, #oralhealth for older people & more.
The relationship between chronic kidney disease (CKD), diabetes, and heart disease is one example of the ways our organs are connected.
The body uses a hormone called insulin to get blood sugar into the body’s cells to be used as energy. If someone has diabetes, their pancreas either doesn’t make enough insulin or can’t use the insulin it makes as well as it should.
If someone has CKD, their kidneys are not able to filter out toxins and waste from their blood as well as they should.
Heart disease refers to several types of heart conditions. The most common condition, coronary artery disease, leads to changes in blood flow to the heart, which can cause a heart attack.
So how are these three conditions connected? Risk factors for each condition are similar and include high blood sugar, high blood pressure, family history, obesity, unhealthy diet, and physical inactivity.
High blood sugar can slowly damage the kidneys, and, over time, they can stop filtering blood as well as they should, leading to CKD. Approximately 1 in 3 adults with diabetes has CKD.
When the kidneys don’t work well, more stress is put on the heart. When someone has CKD, their heart needs to pump harder to get blood to the kidneys. This can lead to heart disease, the leading cause of death in the United States. Change in blood pressure is also a CKD complication that can lead to heart disease.
Luckily, preventing or managing one condition can help you prevent and manage the others and lower the risk for more complications.
Inside the Tufts Health & Nutrition Letter – November 2022:
Abbott Laboratories newest continuous glucose monitor is now available at participating retail pharmacies and through durable medical equipment suppliers. The Freestyle Libre 3 was approved by the FDA in June and is a step up from previous Abbott systems.
Abbott Laboratories and Dexcom are the leaders in the CGM market, which hit $5.1 billion in revenue in 2021 and is expected to reach $13.2 billion by 2028, according to Vantage Market Research. Abbott’s CGM systems, called FreeStyle Libre, generated $3.7 billion in revenue last year, with 4 million users globally.
CNBC’s Erin Black, a type 1 diabetic, tested out the Libre 3 for over a month. Here is her review.
Chapters: 0:00 Intro 0:10 What are cataracts? 0:43 What are the warning signs of cataracts? 2:44 How are cataracts diagnosed? 3:04 Talk to your eye doctor
The October 21, 2022 cover story this week steps back from the news agenda to explore the impact of living with long Covid. For millions of people worldwide who have survived initial infection with the virus, recovery is slow. Symptoms such as breathlessness, fatigue and loss of smell or taste persist for months and, as our science editor Ian Sample explains, treatments that work for some may not be successful for others.
This week delegates to the Chinese Communist party’s 20th congress are in Beijing where they are expected to rubber stamp Xi Jinping’s historic third term as leader. Our big story looks at what the president’s supremacy means for the country and its closest neighbour – Taiwan – which lives in the shadow of Xi’s avowed intention to bring the island back under China’s tutelage.
Andre Terzic, M.D., Ph.D., a Mayo Clinic cardiologist
Regenerative medicine could slow the clock on degenerative diseases that often ravage the golden years, a Mayo Clinic study finds. Life span has nearly doubled since the 1950s, but health span — the number of disease-free years — has not kept pace. According to a paper published in NPJ Regenerative Medicine., people are generally living longer, but the last decade of life is often racked with chronic, age-related diseases that diminish quality of life. These final years come with a great cost burden to society.
Researchers contend that new solutions for increasing health span lie at the intersection of regenerative medicine research, anti-senescent investigation, clinical care and societal supports. A regenerative approach offers hope of extending the longevity of good health, so a person’s final years can be lived to the fullest.
October 2022 – The American Heart Association (AHA) recently revised its checklist for achieving optimal heart health, introducing its new Life’s Essential 8. The list replaces the AHA’s decade-old Life’s Simple 7.
Sleep health is the new addition to the cardiovascular health scoring tool, which now advises that adults get seven to nine hours per night. The organization updated four of the categories:
Using electronic health records data from the All of Us Research Program, we show that higher daily step counts in data collected over several years of Fitbit fitness tracker use were associated with lower risk of common, chronic diseases, including diabetes, hypertension, gastroesophageal reflux disease, depression, obesity and sleep apnea.
Although questions remain about several diet and disease associations, current evidence supports dietary guidelines to limit red meat and increase vegetable intake.
Nature Medicine explores the latest translational and clinical research news, with an analysis of Intellia and Regeneron’s gene-editing treatment, which reduced levels of transthyretin in patients.
As humans live longer, they’re at increased risk of developing devastating NEURODEGENERATIVE diseases, such as Alzheimer’s—in a treatment landscape with few options and little hope. At Scripps Research, scientists are closer than ever to understanding how these diseases harm the brain and identifying possible drugs to stop them.
“This early preclinical work may identify proteins that protect against cognitive loss. We know it’s a long path to get to a drug, but we’re creating the foundation. We know there’s an entire landscape of potential molecular interactions that maintain healthy synapses, and any of these proteins could be a drug target.”— Hollis Cline, PhD
Boomers Daily 