Future Of Trucks: The “GMC Hummer EV” Will Be Revealed In May 2020

GMC Hummer LogoThe all-electric First Ever GMC HUMMER EV leads a quiet revolution – with zero emissions and zero limits. It earns its super truck status with up to:

  • 1000 HORSEPOWER

  • 11,500 LB.-FT OF TORQUE

  • 0-60 MPH IN 3 SECONDS

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Landscape Travel Videos: “Lanzarote – The Wonder” By L’oeil d’Eos (2020)

Raw. Mineral. Bewitchingly. These three words describe perfectly the atmosphere that we could feel on Lanzarote in the Canary archipelago off the coast of Morocco.

Lanzarote The Wonder Landscape Landscapre Travel Film by L'oeil d'Eos 2020
Far from the crowd that can be everywhere on Lanzarote (sometimes), we have found preserved and totally uninhabited places there. It’s this side that we wanted to explore. The soul of its landscapes, of this volcanic lands, between dark rock, stormy ocean and wonderful nature.

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Economics Lectures: “The Great Reversal” Author Thomas Phillippon On Corporate Power (Video)

In this much-anticipated book, a leading economist argues that many key problems of the American economy are due not to the flaws of capitalism or the The Great Reversal Thomas Phillipponinevitabilities of globalization but to the concentration of corporate power. By lobbying against competition, the biggest firms drive profits higher while depressing wages and limiting opportunities for investment, innovation, and growth.

Why are cell-phone plans so much more expensive in the United States than in Europe? It seems a simple question. But the search for an answer took Thomas Philippon on an unexpected journey through some of the most complex and hotly debated issues in modern economics. Ultimately he reached his surprising conclusion: American markets, once a model for the world, are giving up on healthy competition. Sector after economic sector is more concentrated than it was twenty years ago, dominated by fewer and bigger players who lobby politicians aggressively to protect and expand their profit margins. Across the country, this drives up prices while driving down investment, productivity, growth, and wages, resulting in more inequality. Meanwhile, Europe―long dismissed for competitive sclerosis and weak antitrust―is beating America at its own game.

Philippon, one of the world’s leading economists, did not expect these conclusions in the age of Silicon Valley start-ups and millennial millionaires. But the data from his cutting-edge research proved undeniable. In this compelling tale of economic detective work, we follow him as he works out the basic facts and consequences of industry concentration in the U.S. and Europe, shows how lobbying and campaign contributions have defanged antitrust regulators, and considers what all this means for free trade, technology, and innovation. For the sake of ordinary Americans, he concludes, government needs to return to what it once did best: keeping the playing field level for competition. It’s time to make American markets great―and free―again.

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Health: “What Are Hernias & How Are They Repaired?”

Think of a hernia like a bulge in a damaged tire. The inner tube or soft tissue is normally contained by the abdominal wall, and if there is a leak or weak spot the soft tissue like fat or intestines can protrude through. Having a hernia will eventually require surgery to repair, and there are several different ways surgeons go about it.

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Studies: Irregular Sleep Disrupts Pancreatic “Circadian Rhythms”, Leading To Type 2 Diabetes

From a Technology Networks online article:

Technology NetworksBy comparing the pancreatic cells of type 2 diabetic human donors with those of healthy people, researchers at the University of Geneva (UNIGE) and at the University Hospitals of Geneva (HUG), Switzerland, were able to demonstrate, for the first time, that the pancreatic islet cells derived from the Type 2 Diabetic human donors bear compromised circadian oscillators.

The disruption of the circadian clocks was concomitant with the perturbation of hormone secretion. Moreover, using clock modulator molecule dubbed Nobiletin, extracted from lemon peel, the researchers succeeded in “repairing” the disrupted cellular clocks and in partial restoring of the islet cell function. These results, published in the Proceedings of the National Academy of Sciences of the United States, provide a first insight into innovative approach for diabetes care.

PNAS Pancreatic Islets from type 2 diabetes

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The circadian clock system (from Latin “circa diem”, about a day) allows the organisms to anticipate periodical changes of geophysical time, and to adjust to these changes. Nearly all the cells in our body comprise molecular clocks that regulate and synchronize metabolic functions to a 24-hour cycle of day-night changes.

Today, increasing evidence show that disturbances in our internal clocks stemming from frequent time zone changes, irregular working schedules or ageing, have a significant impact on the development of metabolic diseases in human beings, including type-2 diabetes. Such disturbances seem to prevent the proper functioning of the cells in the pancreatic islet that secrete insulin and glucagon, the hormones that regulate blood sugar levels.

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New Travel Books: “Uzbekistan – The Road to Samarkand” (Assouline)

Uzbekistan Assouline Book Cover 2020At the heart of Central Asia lies a land where colossal mountains and sweeping valleys sleep under a blanket of lush greenery. Crowned with golden palaces and wondrous monuments, the architectural landscape of the region is so rich with detail, the structures have been said to mirror the heavens themselves.

One of the few destinations on Earth where imagination aligns with reality, Uzbekistan flourishes with unparalleled scenery and unforgotten traditions. The towns and cities are like ‘open museums’, each edifice offering a unique and intricate aesthetic, each a testament to diverse cultural influences and diverse periods of history. Nature and architecture have a unique relationship, seemingly inspired by each other, as if they were trying to to outdo each other with their beauty. Discover the beautiful colors, textures and flavors of this incredible culture and journey through the cities of the Silk Road and the lands of Alexander The Great with stunning original photography by Laziz Hamani.

ABOUT THE AUTHOR

For over 40 years, Yaffa Assouline has captured the luxury and publishing industry as a journalist, consultant and creative art director. She specializes in innovative and made-to measure publishing. Uzbekistan was inspired by Yaffa’s desire to introduce the world to a country unknown to most: an exotic land filled with immense beauty unseen to most eyes. For more than a year, Yaffa embarked on a journey where she captured the essence of the country, from east to west, north to south, filled with unforgettable encounters along the way. It was a vast undertaking—given a place with such a rich culture, long diverse history and all this beauty to offer—to give a taste of the flavor of the country. The book is an invitation to voyage, to discover more and to see what could only be fully appreciated with one’s own eyes.

Photographer Laziz Hamani, is long-time friend of Yaffa Assouline. With his talent and eye for intimate details, he was the only person who was suited to be Yaffa’s partner – a visual scribe in this adventure. Of Berber origin, he was born and lives in Paris. He is passionate about creating beautiful images, his life defined by a constant search for aesthetics and meaning. He has worked with many prestigious luxury brands, such as Dior, Cartier, Jaeger-LeCoultre and with designer Axel Vervoordt; and he has collaborated with Assouline Publishing on more than twenty titles.

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Science Podcasts: Low-Cost Cryo-Electron Microscopes & Genetic Roots Of Schizophrenia

Science Magazine PodcastsStructural biologists rejoiced when cryo–electron microscopy, a technique to generate highly detailed models of biomolecules, emerged. But years after its release, researchers still face long queues to access these machines. Science’s European News Editor Eric Hand walks host Meagan Cantwell through the journey of a group of researchers to create a cheaper, more accessible alternative.

Cryo-Electron Microscopes

Also this week, host Joel Goldberg speaks with psychiatrist and researcher Goodman Sibeko, who worked with the Xhosa people of South Africa to help illuminate genetic details of schizophrenia. Though scientists have examined this subject among Western populations, much less is known about the underlying genetics of people native to Africa.

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Research: “Designing Tech For Healthy Aging In Place” (UC San Diego Video)

Digital tools including mobile apps, wearable sensors, and social network platforms offer unprecedented opportunities in health research and healthcare. However, this rapidly emerging sector is outpacing existing regulatory structures and challenging norms for ethical practice.

Camille Nebeker, EdD, MS, Associate Professor of Behavioral Medicine in the Department of Family Medicine & Public Health at the UC San Diego School of Medicine describes how technologies, including wearable sensors and artificial intelligence, are leveraged to capture personal health data and infer health status. Nebeker presents the ethical considerations specific to informed consent, risks of harm and potential benefits while underscoring the role that funding agencies, policy makers, researchers, ethicists, and editors have in creating the infrastructure needed to advance safe digital health research and practice.

News, Views and Reviews For The Intellectually Curious