This week’s @TheTLS , featuring @Godwin_lives on Shelley’s unfinished poems; @devoneylooser on Charles Austen and the slave trade; @jeres on the life of a plongeur; @Mika_R_S on Anna Wintour; @RozKaveney on Samuel R. Delany; @nheller on the Buddha’s tooth – and more.
‘Je vois red’ raged Louise Bourgeois (1911–2010) on one of the loose sheets of paper that she made notes on, most often about herself and her work and, in this case, about the painting Natural history #2 (1944; Easton Foundation, New York), which struck her as all going wrong. Slipping between two languages, Bourgeois’s fury conforms to the themes of rage, the death drive and childhood aggression that the art historian Mignon Nixon has traced in the artist’s work in reference to the ideas of the psychoanalyst Melanie Klein.
Interior designer Jamie Bush and architect William Hefner reimagine a dwelling for a client with a dazzlingly eccentric point of view
The Florentine July/August 2022
My forearms are sticking to the desk as I type this month’s letter. It’s an irksome feeling that’s offset by last night’s joy of dancing wildly at a wedding and an afternoon dip in a kind friend’s swimming pool. Summer in Florence is an intoxicating mix of sweat, fun and gelato. While many of us escape to our countries of origin for as long as we can, there’s something undeniably alluring about these sun-streaked months in Tuscany. Just think back to movies such as Stealing Beauty and Under the Tuscan Sun before fast forwarding to recent Netflix films Toscana and Love & Gelato. Stereotypes aside—and there are far too many to mention in these productions (Netflix, we’re here if you fancy delving deeper into our city and region!)—summer in Florence never stops working its inexplicable magic. Yes, the wall of heat and buzz of mosquitoes may be draining during the day, but the night brings boundless pleasures, from movie nights by the Uffizi to exhibitions at just-reopened Forte di Belvedere, refreshing beers beside the Arno and brilliantly oddball cultural moments such as a wheat threshing festival in the hills (find out more about that gem on page 16).
The cover shows an artistic representation of various cancer cells. The large-scale gains, losses and rearrangements of DNA seen in chromosomal instability are a typical feature of cancer — but there is no comprehensive framework to decode the causes of this genomic variability and their possible links to disease. In this week’s issue, Florian Markowetz, Geoff Macintyre and their colleagues present such a framework with a compendium of 17 signatures of chromosomal instability that can be used to predict how tumours might respond to drugs and that help to identify future therapeutic targets. The team created the compendium by examining 7,880 tumours representing 33 types of cancer. In a separate paper, Nischalan Pillay and colleagues examined 9,873 cancers to generate
The promise of a new diet that can add as much as a decade to your life is certainly tempting – and might well be proven to work – but for now should be swallowed with a pinch of salt
Their positions are popular. So why are they going extinct?
@TheTLS – July 1, 2022. Featuring Kenneth Rogoff on inflation; @KuperSimon on the Tour de France; @natsegnit on the ultrawealthy; Terry Eagleton on Geoff Dyer; @amyhawk_ on Hong Kong; @scheffer_pablo on climate change in medieval literature – and more.
Boomers Daily 
