Science Magazine – December 14, 2023: The new issue cover features The 2023 Breakthrough of the Year: Obesity meets its match – Blockbuster weight loss drugs show promise for a wider range of health benefits; Runners-Up: At last, modest headway against Alzheimer’s; and Breakdowns of the Year – What went wrong in the world of Science….
Blockbuster weight loss drugs show promise for a wider range of health benefits
Obesity plays out as a private struggle and a public health crisis. In the United States, about 70% of adults are affected by excess weight, and in Europe that number is more than half. The stigma against fat can be crushing; its risks, life-threatening. Defined as a body mass index of at least 30, obesity is thought to power type 2 diabetes, heart disease, arthritis, fatty liver disease, and certain cancers.
Medicine has had little to offer the tens of millions of people worldwide with Alzheimer’s disease, and the few approved treatments have only targeted symptoms. But in January, U.S. regulators greenlit the first drug that clearly, if modestly, slows cognitive decline by tackling the disease’s underlying biology; a second, related treatment is close behind. Neither comes close to a cure, and both have serious risks, but they offer new hope to patients and families.
Israel is resolved to remove Hamas and its terrorist infrastructure from the Gaza Strip permanently, and for much of the world, its determination raises one question more than any other: What comes next in Gaza? For those who disapprove of Israel’s actions in the war or those who either passively or actively support the role of Hamas as the Strip’s governing authority, the lack of answers provides a pretext not only to demand a permanent cease-fire but to suggest (often quietly and with a furrowed brow indicating supposed realpolitik wisdom) that the path Israel seems to be making for itself is a dead end from which it needs to be saved.
In his new book, The Conservative Futurist: How to Create the Sci-Fi World We Were Promised,American Enterprise Institute scholar James Pethokoukis writes about the go-go years of the 1960s: Saturn V rockets were blasting to the moon, atomic power promised to make electricity “too cheap to meter,” and sci-fi TV shows like Star Trek depicted new marvels right around the corner.
“Joseph,” my friend Edward Shils said to me, “we have spoken about many things, among them about various writers, but we are both too civilized ever to talk about Shakespeare. After all, what could one say?” Yes, what can one say? Over a long writing career, I have never written about Shakespeare, and, best I can recall, among the many millions of words I have produced, have never even quoted him. Truth is, I have long admired Shakespeare without being especially nuts about him.
The Economist Magazine (December 14, 2023): The latest issue features ‘The media and the message’ – Journalism and the 2024 presidential election; ‘Can you have a healthy democracy without a common set of facts?; Iran’s regime is weaker than it looks, and therefore more pliable, and more…
America’s presidential election is a test of that proposition
Journalists should not spend much of their time writing about journalism. The world is more interesting than the inky habits of the people who report on it. But this week we are making an exception, because the discovery and dissemination of information matters a lot to politics. Don’t take our word for it: “A popular government,” wrote James Madison in 1822, “without popular information, or the means of acquiring it, is but a prologue to a farce or a tragedy; or, perhaps both.” Were Thomas Jefferson offered a choice between a government without newspapers and newspapers without a government, he said that he would choose the press (though that is probably going a bit far).
America should deter it from escalating the Gaza war, but also engage with it
Twelve months ago Iran was reeling from protests sparked by the death in custody of a young woman who had been arrested for showing too much hair. Its theocratic regime was increasingly isolated, as Arab states forged closer ties with its enemy, Israel. The economy was a mess, adding to popular anger at Iran’s ageing supreme leader and inept president. The Islamic Republic had not seemed so vulnerable in decades.
Foreign Affairs (December 13, 2023): The new January/February 2024 issue features ‘The Self-Doubting Superpower’ – America shouldn’t give up on the World It Made; The Middle East Remade; Why Israel Slept; Hamas’s Advantage, and more….
Most Americans think their country is in decline. In 2018, when the Pew Research Center asked Americans how they felt their country would perform in 2050, 54 percent of respondents agreed that the U.S. economy would be weaker. An even larger number, 60 percent, agreed that the United States would be less important in the world. This should not be surprising; the political atmosphere has been pervaded for some time by a sense that the country is headed in the wrong direction. According to a long-running Gallup poll, the share of Americans who are “satisfied” with the way things are going has not crossed 50 percent in 20 years. It currently stands at 20 percent.
In a barbaric surprise attack launched by Hamas on October 7, more Jews were slaughtered than on any day since the Holocaust. Thousands of elite Hamas militants from the Gaza Strip infiltrated small communities and cities in southern Israel, where they proceeded to commit sadistic, repulsive crimes against humanity, filming their vile deeds and boasting about them to friends and family back home.
Nature Magazine – December 13, 2023:The latest issue cover features the BRAIN Initiative Cell Census Network (BICCN), which presented nine papers that map the entire mouse brain in unprecedented detail.
The extravagantly feathered Seychelles paradise flycatcher lacks genetic diversity, which might hamper its resilience to climate change and other threats.
Country Life Magazine – December 13, 2023: The latest ‘Double Christmas’ issue features How the Bible’s nativity story has influenced artists; the beauty of the gardens of Rockcliffe in Gloucestershire; In literature at least, the fox will come out on top in almost every brush with confrontation, and more….
Away in a manger
Love, pain, power and hope are all embodied in the Nativity. Michael Prodger examines how the Bible story influenced our greatest artists
The Bishop of Winchester’s favourite painting
The Right Revd Philip Mounstephen chooses an arresting Caravaggio
On the night watch
As darkness falls, the wild things emerge from the shadows. John Lewis-Stempel embraces the night
Prodigy or eccentric?
John Goodall explores Bristol Cathedral, a building of international importance
When Christmas was cancelled
Always winter, never festive: Cromwell’s directive cast a pall, laments Ian Morton
Made with love
Cast your eyes down next time you’re in church to admire the hassock you kneel upon, urges the Revd Colin Heber-Percy
’Tis the season to be busy
There’s no rest for the farmer, the baker or the cheesemonger at this time of year. Ben Lerwill champions the people who make Christmas happen
So, this is Christmas
Queen Victoria would feel quite at home in any of our houses this season, believes John Mueller
It came upon a midnight clear
Come one, come all, says Kate Green, as the villagers gather once more at the big house
The Editor’s Christmas quiz
Pit your wits. The only prize is glory
Luxury
Christian Dior, David Gandy, dinky toys and Sir Chris Hoy’s favourite things
Cold comforts
Frost-dusted and fleece-wrapped, the beauty of the gardens of Rockcliffe in Gloucestershire enchant Tiffany Daneff
It’s a wonderful life
Carla Passino travels the world for Christmas traditions, from Swedish tomte to Japanese KFC
Christmas conundrums
Turkey or goose? Stocking or sack? Port or Sauternes? Giles Kime poses the big questions
Think outside the fox
Clever and agile, Vulpes vulpes is frequently on top in literature. Kate Green turns the pages
Back to black
The Périgord black truffle is worth the price for Tom Parker Bowles
The peel-good factor
The rich scents of citrus permeate Deborah Nicholls-Lee’s Christmas
Sugar, spice and all things nice
Carla Passino builds a gingerbread house
On top of the mirey, merey moor
John Lewis-Stempel tucks his chin into his scarf and sets off into the frozen wastes
Times Literary Supplement (December 13, 2023): The latest issue features ‘Innocent bystanders? – Collaboration with the Third Reich; The contaminated blood scandal; Gertrude Stein and Picasso, Hamlet’s play; AI Journalism and Clarice Lispector calls…
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