Category Archives: Studies

Health Studies: Foods Containing Lactose Feed “Dangerous” Gut Bacteria

From Sloan Kettering Institute:

Enterococcus BacteriaInfections with the Enterococcus bacterium are a major threat in healthcare settings. They can lead to inflammation of the colon and serious illnesses such as bacteremia and sepsis, as well as other complications.

Now, an international team led by scientists from Memorial Sloan Kettering has shown for the first time that foods containing lactose, a sugar that’s naturally found in milk and dairy products, help Enterococcus thrive in the gut, at least in mice. They also studied changes in the bodies of people having BMTs. The study was published November 29 in Science.

Memorial Sloan KetteringTheir previous research has shown that when harmless strains of microbes are wiped out, often due to treatment with antibiotics, Enterococcus and other harmful types of bacteria can take over due to lack of competition. As part of the new study, which included analysis of microbiota samples from more than 1,300 adults having BMTs, the team confirmed the link between Enterococcus and GVHD.

To read more: https://www.mskcc.org/blog/milking-it-study-mice-suggests-lactose-diet-feeds-dangerous-gut-bacteria?_subsite=research-ski

Health Studies: Eating After Exercise Found To Burn “Twice The Fat”

From a New York Times online article:

Journal of Clinical Endocrinology & MetabolismThe riders who had pedaled on an empty stomach, however, had incinerated about twice as much fat during each ride as the men who consumed the shake first. The riders all had burned about the same number of calories while pedaling, but more of those calories came from fat when the men did not eat first.

Those riders also showed greater improvements in insulin sensitivity at the end of the study and had developed higher levels of certain proteins in their muscles that influence how well muscle cells respond to insulin and use blood sugar.

Working out on an empty stomach could amplify the health benefits of the activity, according to a well-timed new study of the interplay of meal timing, metabolic health and moving. The study, which involved sedentary men and moderate cycling, suggests that whether and when we eat may affect how exercise affects us.

To read more: https://www.nytimes.com/2019/11/27/well/move/eating-food-exercise-fasting-insulin-weight-loss-fat.html

Studies: High Usage Of Commonly Used Oral Antibiotics Increases Risk Of Parkinson’s Disease

From a Neuroscience News & Research online article:

International Parkinson and Movement Disorder Society“The link between antibiotic exposure and Parkinson’s disease fits the current view that in a significant proportion of patients the pathology of Parkinson’s may originate in the gut, possibly related to microbial changes, years before the onset of typical Parkinson motor symptoms such as slowness, muscle stiffness and shaking of the extremities. It was known that the bacterial composition of the intestine in Parkinson’s patients is abnormal, but the cause is unclear. Our results suggest that some commonly used antibiotics, which are known to strongly influence the gut microbiota, could be a predisposing factor,” says research team leader, neurologist Filip Scheperjans MD, Ph.D. from the Department of Neurology of Helsinki University Hospital.

Higher exposure to commonly used oral antibiotics is linked to an increased risk of Parkinson’s disease according to a recently published study by researchers from the Helsinki University Hospital, Finland.

The strongest associations were found for broad-spectrum antibiotics and those that act against anaerobic bacteria and fungi. The timing of antibiotic exposure also seemed to matter.

The study suggests that excessive use of certain antibiotics can predispose to Parkinson’s disease with a delay of up to 10 to 15 years. This connection may be explained by their disruptive effects on the gut microbial ecosystem.

To read more: https://www.technologynetworks.com/neuroscience/news/high-antibiotic-use-linked-to-parkinsons-disease-327574?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=79860634&_hsenc=p2ANqtz–_nnD-InNAm660b4dNIgEv57uzmLlk_LytFh7Scy9VWyekeywrdb7g2Be0Cp5uO7DoNsRuPF76EvY99oZ2rHBR9M1iEw&_hsmi=79860634

Health: “Feather Duvet Lung” Left Undiagnosed Risks Irreversible Lung Fibrosis (BMJ Case Reports)

From a British Medical Journal (BMJ) online release:

Feather Duvet LungAlthough he had no pet birds, on closer questioning he had recently acquired a duvet and pillows containing feathers. His symptoms, chest radiograph and lung function tests improved after removal of all feather bedding, and he was also started on oral corticosteroid therapy. Our case reinforces the importance of taking a meticulous exposure history and asking about domestic bedding in patients with unexplained breathlessness. Prompt recognition and cessation of antigen exposure may prevent the development of irreversible lung fibrosis.

A 43-year-old non-smoker was referred with a 3-month history of malaise, fatigue and breathlessness. Blood avian precipitins were strongly positive. Lung function testing confirmed a restrictive pattern with impaired gas transfer. A ‘ground glass’ mosaic pattern was seen on CT imaging, suggestive of hypersensitivity pneumonitis.

Feather duvet lung (FDL), is an immunologically mediated form of hypersensitivity pneumonitis (HP), also sometimes called extrinsic allergic alveolitis. FDL is caused by inhalation of organic dust from duck or goose feathers found in duvets and pillows. Antigen inhalation triggers an immunological cascade, resulting in lung parenchymal inflammation. Repeated exposure may result in irreversible lung fibrosis.

To read more: https://casereports.bmj.com/content/12/11/e231237

Housing Market: A “Silver Tsunami” Of 20+ Million Homes Owned By Baby Boomers Will Flood The Market In Next 20 Years

From a Zillow.com online article:

Currently, 33.9 percent of owner-occupied U.S. homes are owned by residents aged 60 or older, and 55.2 percent by residents aged 50 or older. As these households age and begin vacating housing, that could represent upwards of 20 million homes hitting the market through the mid-2030s.

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The massive Baby Boomer generation has already begun aging into retirement, and will begin passing away in large numbers in coming decades – releasing a flood of currently owner-occupied homes that could hit the market. That could help end the last few years’ inventory drought, as well as a more fundamental shortage of homes in certain places.

This Silver Tsunami of homes coming to market could be a good substitute for new home construction, which has been in short supply for the past decade in large part because of difficult-to-overcome challenges faced by builders.

To read more: https://www.zillow.com/research/silver-tsunami-inventory-boomers-24933/

 

Engineering In Nature: “Honeybees Use Their Wings For Water Surface Locomotion” (Caltech)

From a Caltech online article:

Bees Surf Atop Water to escape CaltechWhen a bee lands on water, the water sticks to its wings, robbing it of the ability to fly. However, that stickiness allows the bee to drag water, creating waves that propel it forward. In the lab, Roh and Gharib noted that the generated wave pattern is symmetrical from left to right. A strong, large-amplitude wave with an interference pattern is generated in the water at the rear of the bee, while the surface in front of the bee lacks the large wave and interference. This asymmetry propels the bees forward with the slightest of force—about 20 millionths of a Newton.

Walking on Caltech’s campus, research engineer Chris Roh (MS ’13, PhD ’17) happened to see a bee stuck in the water of Millikan Pond. Although it was a common-enough sight, it led Roh and his advisor, Mory Gharib (PhD ’83), to a discovery about the potentially unique way that bees navigate the interface between water and air.

To read more: https://www.caltech.edu/about/news/bees-surf-atop-water

Health Studies: NSAIDs (Nonsteroidal Anti-Inflammatory Drugs) Increase Heart Failure Risk For Arthritis Patients

From a Harvard Medical School release:

Harvard Medical SchoolResearchers matched 7,743 people with osteoarthritis with 23,229 healthy people who rarely or never took NSAIDs. People with osteoarthritis had a 42% higher risk of heart failure and a 17% higher risk of coronary artery disease compared with healthy people. After controlling for a range of factors that contribute to heart disease (including high body mass index, high blood pressure, and diabetes), they concluded that 41% of the increased risk of heart disease related to osteoarthritis was due to the use of NSAIDs.

To manage the painful joint disease known as osteoarthritis, people often take ibuprofen (Advil, Motrin) and naproxen (Aleve, Anaprox). But these and related drugs — known as NSAIDs — may account for the higher rates of heart disease seen in people with osteoarthritis, a new study suggests.

To read more: https://www.health.harvard.edu/heart-health/pain-relievers-a-cause-of-higher-heart-risk-among-people-with-arthritis

Health Studies: Reduced Mental Alertness (“Brain Fog”) Is Caused By Inflammation In The Body

From a Genetic Engineering & Biotechnology News release:

NeuroImage Journal“These results show quite clearly that there’s a very specific part of the brain network that’s affected by inflammation,” noted Mazaheri. “This could explain ‘brain fog’.”

Raymond added that “this research finding is a major step forward in understanding the links between physical, cognitive, and mental health and tells us that even the mildest of illnesses may reduce alertness.”

Researchers at the University of Birmingham’s Centre for Human Brain Health in collaboration with the University of Amsterdam say they have uncovered a possible explanation for the mental sluggishness that often accompanies illness. The team investigated the link between “mental fog” and inflammation, the body’s response to illness. In a study (“Selective effects of acute low-grade inflammation on human visual attention”) published in Neuroimage, they showed that inflammation appears to have a particularly negative impact on the brain’s readiness to reach and maintain an alert state.

To read more: https://www.genengnews.com/news/link-found-between-inflammation-and-mental-sluggishness/?utm_medium=newsletter&utm_source=GEN+Daily+News+Highlights&utm_content=01&utm_campaign=GEN+Daily+News+Highlights_20191118&oly_enc_id=5678C5137845J4Z

Brain Health: “Package Of Lifestyle Changes” (Brisk Exercise, Healthy Diet & Sleep, Cognitive Training) Helps Prevent Dementia

From a Wall Street Journal online article:

How Likely is Dementia - Source The Lancet, Gill Livingston, et al.
How Likely Is Dementia?

Dementia is a complicated disease that has multiple causes and risk factors, some of which remain unknown. Nevertheless, there is increasing evidence that people—even those who inherit genes that put them at greater risk of developing Alzheimer’s in later life—can improve their chances by adopting lifestyle changes.

“It’s not just about running three times a week,” says Sarah Lenz Lock, executive director of AARP’s Global Council on Brain Health. “Instead, it’s about a package of behaviors, including aerobic exercise, strength training, a healthy diet, sleep and cognitive training.”

When it comes to battling dementia, the unfortunate news is this: Medications have proven ineffective at curing or stopping the disease and its most common form, Alzheimer’s disease. But that isn’t the end of the story. According to a recent wave of scientific studies, we have more control over our cognitive health than is commonly known. We just have to take certain steps—ideally, early and often—to live a healthier lifestyle.

In fact, according to a recent report commissioned by the Lancet, a medical journal, around 35% of dementia cases might be prevented if people do things including exercising and engaging in cognitively stimulating activities. “When people ask me how to prevent dementia, they often want a simple answer, such as vitamins, dietary supplements or the latest hyped idea,” says Eric Larson, a physician at Kaiser Permanente in Seattle and one of a group of scientists who helped prepare the report. “I tell them they can take many common-sense actions that promote health throughout life.”

To read more: https://www.wsj.com/articles/what-science-tells-us-about-preventing-dementia-11574004600