From a Science Journal study (Feb 21, 2020):
We suggest this increase in mortality seen on DR in the 4-day switch treatment is due to either accrued physiological costs or more probable, a carryover of deaths directly resulting from the rich diet, but recorded on the DR diet.
A closer examination of the timing of mortality within the 4-day switching paradigm showed that the mortality response was strongest in the second 48 hours after exposure to both DR and rich diets.
Ageing has attracted extensive scientific interest, from both a fundamental and biomedical perspective. Dietary restriction (DR) extends health and life span across taxa, from baker’s yeast to mice, with very few exceptions (1, 2). The reduction in total calories—or restriction of macronutrients, such as protein—extends life span reliably (3–5). Although the precise universal mechanisms that connect DR to ageing remain elusive, translation of DR’s health benefits to human medicine is deemed possible. The widespread assumption of DR’s translational potential originates from the notion that DR’s beneficial effects are facilitated by shared evolutionary conserved mechanisms, as beneficial effects of DR are observed across taxa.
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This small device may change how doctors identify and manage patients with atrial fibrillation, an irregular heart rhythm that increases risk of stroke.
And the past. The device uses artificial intelligence, or AI, to not only determine if a person is in the midst of an episode of atrial fibrillation, but also it can reveal if they’ve had the irregular rhythm before or will have it in the future.
Dr. Paul Friedman and his team trained the device to detect subtle changes in the heart’s electrical signals. Then in a study, they found it can identify patients with episodic atrial fibrillation. Even when they record the heart while the rhythm is normal – something no current wearable heart monitor can do.
That’s because a heart monitor won’t detect atrial fibrillation unless you have an episode while wearing it. But in a matter of moments, the AI device can identify people with atrial fibrillation, even if their heart is in normal rhythm. Then they can get on the right treatment to help prevent life-threatening strokes from happening.
From a Neuroscience News & Research online article:
“The link between antibiotic exposure and Parkinson’s disease fits the current view that in a significant proportion of patients the pathology of Parkinson’s may originate in the gut, possibly related to microbial changes, years before the onset of typical Parkinson motor symptoms such as slowness, muscle stiffness and shaking of the extremities. It was known that the bacterial composition of the intestine in Parkinson’s patients is abnormal, but the cause is unclear. Our results suggest that some commonly used antibiotics, which are known to strongly influence the gut microbiota, could be a predisposing factor,” says research team leader, neurologist Filip Scheperjans MD, Ph.D. from the Department of Neurology of Helsinki University Hospital.
Higher exposure to commonly used oral antibiotics is linked to an increased risk of Parkinson’s disease according to a recently published study by researchers from the Helsinki University Hospital, Finland.
The strongest associations were found for broad-spectrum antibiotics and those that act against anaerobic bacteria and fungi. The timing of antibiotic exposure also seemed to matter.
The study suggests that excessive use of certain antibiotics can predispose to Parkinson’s disease with a delay of up to 10 to 15 years. This connection may be explained by their disruptive effects on the gut microbial ecosystem.
To read more: https://www.technologynetworks.com/neuroscience/news/high-antibiotic-use-linked-to-parkinsons-disease-327574?utm_campaign=NEWSLETTER_TN_Breaking%20Science%20News&utm_source=hs_email&utm_medium=email&utm_content=79860634&_hsenc=p2ANqtz–_nnD-InNAm660b4dNIgEv57uzmLlk_LytFh7Scy9VWyekeywrdb7g2Be0Cp5uO7DoNsRuPF76EvY99oZ2rHBR9M1iEw&_hsmi=79860634