Tag Archives: Inflammation

Science: Accupuncture’s Inflammation Effect, Antibiotics & Gut Bacteria

The neurons behind acupuncture’s effect on inflammation, and how antibiotics affect gut bacteria.

In this episode:

00:54 The neuronal basis for acupuncture’s effect on inflammation

In mice, electroacupuncture has been shown to reduce inflammation, but only when certain points on the body are stimulated. Why this is has puzzled scientists, but now, researchers have identified the specific neurons that are involved. They hope that this knowledge could be used in future to help treat certain inflammatory-related diseases.

Research article: Liu et al.

News and Views: Electroacupuncture activates neurons to switch off inflammation

07:28 Research Highlights

The Aztec origins of an obsidian ‘spirit mirror’, and the damage done by a Soviet plutonium complex.

Research Highlight: A ‘spirit mirror’ used in Elizabeth I’s court had Aztec roots

Research Highlight: Cold-war spy pictures reveal a Soviet nuclear ‘cloud generator’

10:18 Assessing antibiotics’ collateral damage.

Antibiotics are known to cause damage to the communities of bacteria that live in our guts. To better understand why this happens, a team has mapped the effects that different antibiotics have on individual gut-bacteria species, which may offer new insights into preventing this collateral damage.

Research article: Maier et al.

17:32 Briefing Chat

We discuss some highlights from the Nature Briefing. This time, the latest species to be declared extinct in the US, and a potential planet that orbits three stars.

New York Times: Protected Too Late: U.S. Officials Report More Than 20 Extinctions

New York Times: This May Be the First Planet Found Orbiting 3 Stars at Once

Health: Foods That Fight Inflammation (Harvard)

Covid-19 Analysis: The Negative Health Effects Of Microbiome Loss (PNAS)

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Health: ‘How Covid-19 Affects The Brain’ (Video)

New research could help explain why thousands of Covid-19 survivors are facing debilitating neurological symptoms months after initially getting sick. WSJ breaks down the science behind how the coronavirus affects the brain, and what this could mean for long-haul patients. Illustration: Nick Collingwood/WSJ

Diet Studies: Benefits Of “Time-Restricted Eating” (TRE) Improve With Greater Time Restriction

From iScience / Cell.com (June 26, 2020):

iScience June 26 2020…the beneficial effects of TRE are dose dependent, with greater reductions in body weight, fat mass, and improvement in glucose tolerance when a 9-h protocol was implemented versus 12 and 15 h. The optimal TRE time frame to recommend for people has not been tested. Clear improvements have been noted after 6-, 8-, 9-, and 10-h protocols. It is likely that the greater time restriction would result in greater weight losses, which may maximize the metabolic benefits.

Eating out of phase with daily circadian rhythms induces metabolic desynchrony in peripheral metabolic organs and may increase chronic disease risk. Time-restricted eating (TRE) is a dietary approach that consolidates all calorie intake to 6- to 10-h periods during the active phase of the day, without necessarily altering diet quality and quantity.

Time-Restricted Eating

TRE reduces body weight, improves glucose tolerance, protects from hepatosteatosis, increases metabolic flexibility, reduces atherogenic lipids and blood pressure, and improves gut function and cardiometabolic health in preclinical studies. This review discusses the importance of meal timing on the circadian system, the metabolic health benefits of TRE in preclinical models and humans, the possible mechanisms of action, the challenges we face in implementing TRE in humans, and the possible consequences of delaying initiation of TRE.

Read full study

Podcast: “MedDiet” Alters Gut Micriobiome In Older People, Improves Frailty, Cognition, Inflammation

We observed that increased adherence to the MedDiet modulates specific components of the gut microbiota that were associated with a reduction in risk of frailty, improved cognitive function and reduced inflammatory status. 

Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Paul O’Toole; who is Professor of Microbial Genomics, Head of School of Microbiology and Principal Investigator in APC Microbiome Ireland, an SFI funded centre at University College Cork, Ireland, on “Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across 5 European countries” published in paper copy in Gut in July 2020.

Read article in BMJ Journal “Gut”

Top New Science Podcasts: Covid-19 Inflammatory Response, Glacier Retreat

science-magazine-podcastsFirst up this week, Staff Writer Jennifer Couzin-Frankel talks with host Sarah Crespi about a rare inflammatory response in children that has appeared in a number of COVID-19 hot spots. 

Next, Julian Dowdeswell, director of the Scott Polar Research Institute and professor of physical geography at the University of Cambridge, talks with producer Meagan Cantwell about tracing the retreat of Antarctica’s glaciers by examining the ocean floor. Finally, Kiki Sanford interviews author Danny Dorling about his new book, Slowdown: The End of the Great Acceleration―and Why It’s Good for the Planet, the Economy, and Our Lives.