Tag Archives: Virus

Coronavirus/Covid-19: Francis Crick Institute On “Large-Scale, Reliable Testing” (LRB Podcast)

London Review of Books logoRupert Beale talks again to Thomas Jones about his work at the Francis Crick Institute, where he’s helping to set up a testing lab for Covid-19.

He talks about the challenges of creating a scalable process, explains why a successful antibody test could be hard to achieve, and finds some reasons to be hopeful.

You can find a full transcript of this episode HERE.

Coronavirus (COVID-19): Safe Shopping at Stores and Pharmacies (JAMA)

JAMA Clinical Reviews LogoFood and medicine shopping is essential during the COVID-19 pandemic, but requires getting out and standing close to strangers at a time when social distancing and sheltering-in-place are recommended to slow spread of disease.

David Aronoff, MD, director of the Division of Infectious Diseases at Vanderbilt University in Nashville, explains how to minimize COVID-19 risk while shopping.

 

Podcasts: How Foreign Governments Are Facing Covid-19 (The Economist)

A selection of essential articles read aloud from the latest issue of The Economist. This week, the role of big government in the time of covid-19, (10:20) assessing the havoc the pandemic is causing in emerging countries, (17:45).

In just a few weeks a virus a ten-thousandth of a millimetre in diameter has transformed Western democracies. States have shut down businesses and sealed people indoors. They have promised trillions of dollars to keep the economy on life support. If South Korea and Singapore are a guide, medical and electronic privacy are about to be cast aside. It is the most dramatic extension of state power since the second world war.

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Hospitals & Coronavirus: Emergency Room Doctor Discusses Preparing For Cases In Miami Area (NEJM)

NEJM talks with Dr. Julian Flores, who works in a Broward County, Florida, emergency room.

NEJM Journal WatchWhen he was interviewed, the count of Covid-19 cases stood at 412, less than 12 hours later, the new number was 505. He’s expecting the wave to hit hard there. Broward is home to Fort Lauderdale (think spring break) and Pompano Beach (think aging retirees). Couple those demographics with a lack of easy testing for the virus, and you’ve got a worrisome situation.

Health: Scripps Research “DETECT” Wearable APP Study – A Viral Illness Early Warning System

DETECT Health Study for Wearables AppWhen your heart beats faster than usual, it can mean that you’re coming down with a cold, flu, coronavirus, or other viral infection. That’s the conclusion of recent medical research.

So wearable devices that measure your resting heart rate—made by Apple, Fitbit, Garmin, and others—might help scientists spot viral outbreaks, and also give you more insight into your own health.

Scripps Research designed DETECT (Digital Engagement & Tracking for Early Control & Treatment), a study that will monitor your heart rate and allow you to record symptoms like fever or coughing.

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Coronavirus: “Do Face Masks Work? Do They Protect People?” (BBC)

As coronavirus continues to spread around the world, face masks are in high demand as people look for ways to protect themselves. But do they really protect most people from contracting the virus? Dr Shunmay Yeung from London School of Hygiene and Tropical Medicine explains.

Health Update: Ibuprofen Results In “More Severe Illness” For “Coronavirus / Covid-19” Patients (BMJ)

From a BMJ online release (March 17, 2020):

Acetaminophen Bottle“The finding in two randomised trials that advice to use ibuprofen results in more severe illness or complications helps confirm that the association seen in observational studies is indeed likely to be causal. Advice to use paracetamol (acetaminophen) is also less likely to result in complications.”

Scientists and senior doctors have backed claims by France’s health minister that people showing symptoms of covid-19 should use paracetamol (acetaminophen) rather than ibuprofen, a drug they said might exacerbate the condition.

The BMJIan Jones, a professor of virology at the University of Reading, said that ibuprofen’s anti-inflammatory properties could “dampen down” the immune system, which could slow the recovery process. He added that it was likely, based on similarities between the new virus (SARS-CoV-2) and SARS I, that covid-19 reduces a key enzyme that part regulates the water and salt concentration in the blood and could contribute to the pneumonia seen in extreme cases. “Ibuprofen aggravates this, while paracetamol does not,” he said.

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Coronavirus / Covid -19: “What Happens When It Enters Your Body” (Video)

The Telegraph LogoWhat happens when you catch coronavirus? The Telegraph’s Global Health Security Editor Paul Nuki explains all the ways in which you could become infected with COVID-19 and how your body reacts to this virus.

What happens when the virus enters the body?

When the virus enters your body it binds to two cells in the lungs – goblet cells that produce mucus and cilia cells which have hairs on them and normally prevent your lungs filling up with debris and fluid such as virus and bacteria and particles of dust and pollen.

The virus attacks these cells and starts to kill them – so your lungs begin to fill with fluid making it hard for you to breathe. This phase of the disease is thought to last about a week.

At this point your immune system will start to kick in and fight off the invaders. You will develop a fever and your high body temperature will create a hostile environment for the virus. You will start to get rid of the mucus in the form of coughing and a runny nose.

But in some people – particularly the elderly and those with other health conditions – the immune system can go into overdrive. As well as killing the virus it also starts to kill healthy cells.

This heightened immune response can trigger a “cytokine storm” – white blood cells activate a variety of chemicals that can leak into the lungs, which along with the attack on the cells damages them even further. Scans of the lungs show “ground-glass” opacity and then “crazy paving” patterns, as they fill with mucus making it harder and harder to breathe.

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Health: All Adults 18-79 Should Be Screened For Hepatitis C Virus (HCV)

From a Stanford University online article (March 2, 2020):

Health Policy Stanford“The opioid epidemic has added fuel to the HCV fire, substantially increasing transmission,” said Owens. “HCV is now an enormous public health problem, affecting a much broader age range of people than before. Fortunately, we have the tools to identify people and treatment is now successful in the vast majority of patients, so screening can prevent the mortality and morbidity from HCV.”

A task force of national health experts recommends clinicians screen all adults 18 to 79 for the hepatitis C virus (HCV), noting that the viral infection is now associated with more deaths in the United States than the top 60 reportable infectious diseases combined. Many people are unaware they are carrying the viral infection.

CDC-viral-hepatitis-work-P-page-0

“People with hepatitis C do not always feel sick and may not know they have it,” says chair of the U.S. Preventive Services Task Force Douglas K. Owens, M.D, M.S. “Screening is key to finding this infection early, when it’s easier to treat and cure, helping reduce illnesses and deaths.”

Owens, who is the director of Stanford Health Policy and the Henry J. Kaiser, Jr., Professor of Medicine, said the opioid epidemic now plays an important role in the prevalence of HCV. There are more than three times the number of acute HCV cases than a decade ago, particularly among young, white, injection drug users who live in rural areas. Women aged 15 to 44 have also been hit hard by the virus that is spread through contaminated blood.

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