Tag Archives: CRISPR

Research Preview: Nature Magazine Dec 14, 2023

Volume 624 Issue 7991

Nature Magazine – December 13, 2023: The latest issue cover features the BRAIN Initiative Cell Census Network (BICCN), which presented nine papers that map the entire mouse brain in unprecedented detail.

BICCN: The first complete cell census and atlas of a mammalian brain

Generating a complete multimodal cell census and atlas of the mouse brain through collaborative data collection, tool development and analysis.

How immense mountains create one of the rainiest places on Earth

The western coast of Colombia can get more than 26 metres of rain a year, thanks to the influence of air jets hitting the Andes range.

This bird escaped extinction — but its genes hint at an ominous future

The extravagantly feathered Seychelles paradise flycatcher lacks genetic diversity, which might hamper its resilience to climate change and other threats.

Research Preview: Nature Magazine Dec 7, 2023

Volume 624 Issue 7990

Nature Magazine – December 6, 2023: The latest issue cover features Internal Clocks – Blood proteins reveal age of human organs to help track health and disease…

A 27,000-year-old pyramid? Controversy hits an extraordinary archaeological claim

The massive buried structures at Gunung Padang in Indonesia would be much older than Egypt’s great pyramids — if they’re even human constructions at all.

Humanity’s oldest art is flaking away. Can scientists save it?

Ancient humans painted scenes in Indonesian caves more than 45,000 years ago, but their art is disappearing rapidly. Researchers are trying to discover what’s causing the damage and how to stop it — before the murals are gone forever.

Tinkering with immune cells gives cancer treatment a boost

Tumours respond more readily to radiation and other therapies in mice without a specific protein in their dendritic cells.

Research Preview: Nature Magazine – Nov 30, 2023

Volume 623 Issue 7989

Nature Magazine – November 29, 2023: The latest issue cover features trails left by satellites, including BlueWalker 3, a prototype communications satellite, as they pass across the sky.

‘Early dark energy’ fails to solve mystery of cosmic expansion

The extra ingredient would explain why the Universe is expanding so fast now — but conflicts with data from ancient quasars.

Huge California wildfires seeded cirrus clouds half a world away

Smoke from record-breaking fires in 2020 travelled all the way to Cyprus, where it helped to trigger cloud formation.

These falcons excel at problem-solving — and outdo some of the world’s smartest birds

A bird of prey called the striated caracara can figure out puzzles that are a struggle for Goffin’s cockatoos, which are known for their intelligence.

Research Preview: Nature Magazine – Nov 23, 2023

B 8G4L/ChimeraX

Volume 623 Issue 7988

Nature Magazine – November 23, 2023: The latest issue cover features how cryo-electron microscopy can reveal the structure of motor protein myosin filaments, which power the heart via muscle contraction.

Earth just had its hottest year on record — climate change is to blame

Around 7.3 billion people faced temperatures strongly influenced by global warming over the past year.

UK first to approve CRISPR treatment for diseases: what you need to know

The landmark decision could transform the treatment of sickle-cell disease and β-thalassaemia — but the technology is expensive.

How AI is expanding art history

From identifying disputed artworks to reconstructing lost masterpieces, artificial intelligence is enriching how we interpret our cultural heritage.

Previews: The New Yorker Magazine – Sept 11, 2023

Office space and mall.

The New Yorker – September 11, 2023 issue: The new issue features Dana Goodyear on editing humans with crispr, Elizabeth Kolbert on decoding whale communication, James Wood on George Eliot, and more.

The Transformative, Alarming Power of Gene Editing

Hands cutting DNA with a pair of scissors. Growth of a human baby is displayed in the background.

A rogue scientist showed that crispr gives humans the ability to transform ourselves. But should we?

By Dana Goodyear

Crispr, which may be the single most transformative biological technology of the twenty-first century, is a natural phenomenon, evolved over billions of years. It was first observed in the nineteen-eighties, when researchers noticed unexplained sequences of viral DNA in E. coli. Eventually, they realized that these sequences played a role in the bacteria’s immune system: they could find and destroy other pieces of viral DNA. 

The Holy Heresies of George Eliot

Two people lying with their faces close to each other with their long hair flowing over an open book

Her greatest rebellion against Victorian moralism was to reclaim the sacred for herself.

By James Wood

Literature bores me, especially great literature,” the narrator of one of John Berryman’s “Dream Songs” says. George Eliot sometimes bores me, especially the George Eliot draped in greatness. Think of the extremities of nineteenth-century fiction: labile Lermontov; crazy, visionary Melville; nasty, world-hating Flaubert; mystic moor-bound Brontës; fanatical, trembling Dostoyevsky; explosive Hamsun. There’s enough wildness to destroy the myth of that stable Victorian portal “classic realism.” It was not classic—certainly not then—and not always particularly “real.”

Preview: MIT Technology Review – January/Feb 2023

JF23 cover

MIT Technology Review – January/February 2023:

10 Breakthrough Technologies 2023

Our annual look at 10 Breakthrough Technologies—including CRISPR for high cholesterol, battery recycling, AI that makes images, and the James Webb Space Telescope—that will have a profound effect on our lives. Plus care robots, 3-D printing pioneers, and chasing bugs on the blockchain.

Generative AI is changing everything. But what’s left when the hype is gone?

No one knew how popular OpenAI’s DALL-E would be in 2022, and no one knows where its rise will leave us.

AI is bringing the internet to submerged Roman ruins

The technology is making it easier to monitor underwater archaeological sites.

Research Preview: Science Magazine – Nov 25, 2022

Image

Science Magazine – November 25, 2022 issue:

Cell engineering

The successful use of engineered white blood cells (cells that are removed from the human body, modified with receptors that allow them to recognize cancer cells, and then returned to the body) to fight and eliminate tumor cells has frequently been called revolutionary and has even allowed researchers the rare opportunity to refer to a cure for certain cancers.

How to regrow a forest? Scientists aren’t sure

Reforestation has become a global priority but evidence on what works is still scant

‘Ancestry problem’ sends CRISPR astray in some people

Reference genomes used to direct the gene editor fail to account for human diversity in those of African descent

AI learns the art of Diplomac

Meta’s algorithm tackles both language and strategy in a classic board game that involves negotiationNASA mulls end for long-lived climate sentinels

NASA mulls end for long-lived climate sentinels

Drifting satellites could still yield insights into wildfires and storms, researchers argue

Research Preview: Nature Magazine – Nov 17, 2022

Volume 611 Issue 7936

nature – November 17, 2022 issue:

Farming feeds the world. We desperately need to know how to do it better

Interventions designed to improve agricultural practices often lack a solid evidence base. A new initiative could change that.

CRISPR cancer trial success paves the way for personalized treatments

‘Most complicated therapy ever’ tailors bespoke, genome-edited immune cells to attack tumours.

Overhyping hydrogen as a fuel risks endangering net-zero goals

Hydrogen is touted as a wonder fuel for everything from transport to home heating — but greener and more efficient options are often available.

A fortune in gold is buried in electronic waste

US consumers could generate more than one billion pieces of e-waste a year by 2033.

Why older people get less protection from flu vaccines

Immune players called B cells are partly to blame for the decline in vaccine efficacy for people over 65.

Science: Future Of Energy, Amazon Rainforest, CRISPR

The war in Ukraine has sparked an energy crisis, as European countries attempt to cut ties with Russia. The team discusses what this means for the future of energy production and how it may speed up our pivot to renewable energy. They also explore the growing concerns at various nuclear sites in Ukraine, as some have been seized by the Russians, while others have been damaged during the conflict.

For the first time a virgin birth has taken place in a mammal – a female mouse has given birth without any input from a male. The team explains how CRISPR gene editing has been used to create embryos from unfertilised eggs.

As the Amazon rainforest becomes less resilient to drought, there are fears it may be passing a tipping point that could turn the whole system from forest into savannah. Earth system scientist Tim Lenton of the University of Exeter explains the devastating global impact this would have.

Taking a much-needed trip off the planet, the team discusses two stories from Mars, one from NASA’s Perseverance rover and another from China’s Zhurong rover. We also present an audio space-quiz you can take part in! Thanks to NASA/JPL-Caltech/LANL/CNES/CNRS/ISAE-Supaéro for the audio clips. 

And legendary cosmologist Martin Rees shares his thoughts on the existence of extraterrestrial intelligence in the universe and the fascinating concept of ‘secular’ intelligent design.

On the pod are Rowan Hooper, Penny Sarchet, Matt Sparkes, Adam Vaughan and Richard Webb. To read about these stories and much more, subscribe at newscientist.com/podcasts.

Research: How CRISPR Can Save Lives And End Disease

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA.