From a New Atlas online article:
Scientists have just discovered a new mechanism that can be key in regulating these immune attacks, raising new hopes of drugs that can protect against joint inflammation and the ailments it can bring.
Through the use of the CRISPR gene-editing tool, the Karolinska Institutet scientists have now shed further light on the role they play in inflammation. The technology enabled the team to make adjustments to a set of hand-picked immune cell genes as a way of learning how those tweaks can impact the behavior of the cells.
“The results we obtained using CRISPR were key to quickly understanding how the system under study is regulated,” says Dr Wermeling. “I have high hopes that the experimental use of CRISPR will be hugely important to our understanding of how immune-cell behavior is regulated, and that this can guide us in the development of new efficacious drugs.”

Though a law requiring clinical trial results reporting has been on the books for decades, many researchers have been slow to comply. Now, 2 years after the law was sharpened with higher penalties for noncompliance, investigative correspondent Charles Piller took a look at the results. He talks with host Sarah Crespi about the investigation and a surprising
“When you listen and really grasp what another person is saying, your brainwaves and those of the speaker are literally in sync. By looking at brain scans, neuroscientists have found that the greater overlap and similarity of neural impulses between speaker and listener, the greater the understanding. It’s observable, measurable proof of listening, comprehension, and connection. You know it’s happening when you have that “Oh I get it” moment or sense of clarity when someone else is talking. You’re on the same wavelength, even if you don’t necessarily agree.”
Getting into an MRI machine can be a tight fit for just one person. Now, researchers interested in studying face-to-face interactions are attempting to
The science center is an adolescent among museum types, one whose main growth spurt was in recent memory. Over the past 40 years, they went from a sparse to a ubiquitous presence, now found in almost every major city. Their emergence stretched the ontological essence of the museum: They present not objects, but concepts. Many science centers define themselves explicitly this way and possess slim to no permanent collections.
In this episode of the podcast, Nature reporter Davide Castelvecchi joins us to talk about the big science events to look out for in 2020. We’ll hear about multiple missions to Mars, a prototype electric car, efforts to prevent dengue, and more.
Interview of Professor Mark Post by Monocle 24 “The Bulletin with UBS” podcast aired January 6, 2020.