Tag Archives: Heart Disease

Health Studies: Women’s Blood Vessels Age Faster Than Men’s, Increasing Heart Disease Risks

From a Cedars-Sinai.org online release:

Cedars Sinai logo“Our data showed that rates of accelerating blood pressure elevation were significantly higher in women than men, starting earlier in life,” said Cheng, the Erika J. Glazer Chair in Women’s Cardiovascular Health, who also serves as director of Cardiovascular Population Sciences at the Barbra Streisand Women’s Heart Center. “This means that if we define the hypertension threshold the exact same way, a 30-year old woman with high blood pressure is probably at higher risk for cardiovascular disease than a man with high blood pressure at the same age.”

Women's Blood Vessels Age Faster Than Men;s Cedars-Sinai January 15 2020

(January 15, 2020) – New research from the Smidt Heart Institute at Cedars-Sinai showed for the first time that women’s blood vessels – including both large and small arteries – age at a faster rate than men’s. The findings, published Wednesday in the journal JAMA Cardiology, could help to explain why women tend to develop different types of cardiovascular disease and with different timing than men.

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Health: Heart Disease, Stroke Deaths Are Rising, Even In Healthy States

From a Wall Street Journal online article (01/14/20):

Americans are dying of heart disease and strokes at a rising rate in middle age, normally considered the prime years of life. An analysis of U.S. mortality statistics by The Wall Street Journal shows the problem is geographically widespread. 

Heart Disease Management by age group WSJ from National Center for Health Statistics CDCDeath rates from cardiovascular disease among people between the ages of 45 and 64 are rising in cities all across the country, including in some of the most unlikely places.

In the Journal’s analysis, three metro areas east of Colorado’s Rocky Mountains—Colorado Springs, Fort Collins and Greeley—recorded some of the biggest increases. Death rates in each rose almost 25%. The three cities boast robust access to exercise and health care. There are bike trails, good heart-disease treatment-and-prevention programs and nearby skiing and hiking.

Wall Street Journal Logo Heart Disease Article January 14 2020

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Aortic Stenosis: Early Aortic-Valve Replacement Surgery Lowers Mortality

Early Surgery or Conservative Care for Aortic Stenosis New England Journal of Medicine January 8 2020 Infographic

CONCLUSIONS

Among asymptomatic patients with very severe aortic stenosis, the incidence of the composite of operative mortality or death from cardiovascular causes during the follow-up period was significantly lower among those who underwent early aortic-valve replacement surgery than among those who received conservative care.

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Heart Studies: Alcohol Abstinence For Atrial Fibrillation Reduces Arrhythmia (NEJM)

Alcohol Abstinence for Atrial Fibrillation New England Journal of Medicine January 1 2020

Abstinence from alcohol reduced arrhythmia recurrences in regular drinkers with atrial fibrillation. 

New England Journal of Medicine

January 2, 2020 Atrial fibrillation is the most common sustained arrhythmia,1 and alcohol is consumed by a majority of U.S. adults.2 The current study showed that among regular drinkers, a substantial reduction in alcohol consumption by patients with symptomatic atrial fibrillation was associated with a reduction in recurrence of atrial fibrillation and a reduced proportion of time spent in atrial fibrillation. Earlier meta-analyses showed that alcohol was associated with a dose-related increased risk of incident atrial fibrillation, with increased risk observed even among drinkers who consumed as few as 7 drinks per week.8 Current trends show a rise in alcohol consumption among adults older than 60 years of age,2coupled with greater prevalence of atrial fibrillation in this age group. The present study, with participants having an average intake of approximately 17 drinks per week at baseline, suggests that consumption at these levels may contribute to atrial fibrillation.

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Health Studies: Regular, Brisk Exercise Lowers Inflammatory Cells, Heart Disease Death Risks

From a Science Magazine online article:

Science Magazine Nov 29 2019They found that these physically active mice had fewer inflammatory cells (leukocytes) than sedentary mice, an effect they traced to diminished activity of hematopoietic stem and progenitor cells (HSPCs). The lower activity of HSPCs was due at least in part to exercise-induced reduction in the levels of leptin, a hormone produced by fat tissue that regulates cells within the hematopoietic bone marrow niche.

Regular physical activity is associated with a lower rate of death from heart disease, but the underlying mechanisms are not fully understood. Frodermann et al. examined the effect of exercise on cardiovascular inflammation, a known risk factor for atherosclerosis, by studying mice that voluntarily ran for long distances on exercise wheels.

To read more: https://science.sciencemag.org/content/366/6469/1091.2

 

Heart Disease: Stents, Bypass Surgery Provide No Benefits To Stable Patients In Large Funded Trial

From a Stanford Medicine online release:

Stent in Coronary Artery“For patients with severe but stable heart disease who don’t want to undergo these invasive procedures, these results are very reassuring,” said David Maron, MD, clinical professor of medicine and director of preventive cardiology at the Stanford School of Medicine, and co-chair of the trial, called ISCHEMIA, for International Study of Comparative Health Effectiveness with Medical and Invasive Approaches. 

“The results don’t suggest they should undergo procedures in order to prevent cardiac events,” added Maron, who is also chief of the Stanford Prevention Research Center.

Patients with severe but stable heart disease who are treated with medications and lifestyle advice alone are no more at risk of a heart attack or death than those who undergo invasive surgical procedures, according to a large, federally-funded clinical trial led by researchers at the Stanford School of Medicine and New York University’s medical school.

The trial did show, however, that among patients with coronary artery disease who also had symptoms of angina — chest pain caused by restricted blood flow to the heart — treatment with invasive procedures, such as stents or bypass surgery, was more effective at relieving symptoms and improving quality of life.

To read more: http://med.stanford.edu/news/all-news/2019/11/invasive-heart-treatments-not-always-needed.html

Studies: Surging Number Of Deaths From Heart Failure Tied To Aging Population, Obesity Rates

From a Wall Street Journal online article:

The rapid aging of the population, together with high rates of obesity and diabetes in all ages, are pushing both the rate and number of deaths from heart failure higher, the study said. Most deaths from heart failure occur in older Americans, but they are rising in adults under 65, too, the study showed.

Heart Failure Increase in Aging PopulationThe findings help explain why a decadeslong decline in the death rate from cardiovascular disease has slowed substantially since 2011 and started rising in middle-aged people, helping drive down U.S. life expectancy.

Deaths from heart failure, one of the nation’s biggest killers, are surging as the population ages and the health of younger generations worsens.

The death rate from the chronic, debilitating condition rose 20.7% between 2011 and 2017 and is likely to keep climbing sharply, according to a study published Wednesday in the journal JAMA Cardiology.

To read more: https://www.wsj.com/articles/heart-failure-deaths-rise-contributing-to-worsening-life-expectancy-11572411901

Health Studies: Exercise Found To Improve Blood Vessels For People With Heart Failure

From a Science Daily online release:

“People with heart failure cannot do everything that a healthy individual can, so the question becomes how much exercise can they handle and what type of impact will it have on their health,” Emter said. “We found that regardless of intensity level, some type of physical activity was good for heart health compared to no exercise at all.”

Artery Stiffness

Now, research from the University of Missouri has found exercise can improve the health of blood vessels in the heart for people with heart failure. The finding is based on a study looking at swine, which have very similar blood vessels and heart muscles — both structurally and functionally — as humans.

To read more: https://www.sciencedaily.com/releases/2019/10/191022174402.htm

Health Studies: Early Heart Disease Is Related More To Poor Lifestyle Choices Than Genetics

From a ScienceDaily.com online release:

Eurpean Society of CardiologyPhysical inactivity, smoking, high blood pressure, diabetes, and high cholesterol play a greater role than genetics in many young patients with heart disease, according to research presented today at ESC Congress 2019 together with the World Congress of Cardiology. The findings show that healthy behaviours should be a top priority for reducing heart disease even in those with a family history of early onset.

The study enrolled 1,075 patients under 50, of whom 555 had coronary artery disease (known as premature CAD). Specific conditions included stable angina, heart attack, and unstable angina. The average age was 45 and 87% were men. Risk factor levels and genetics in patients were compared to a control group of 520 healthy volunteers (average age 44, and 86% men). Patients and controls were recruited from the Genes in Madeira and Coronary Disease (GENEMACOR) database.

Five modifiable risk factors were assessed: physical inactivity, smoking, high blood pressure, diabetes, and high cholesterol. Nearly three-quarters (73%) of patients had at least three of these risk factors compared to 31% of controls. In both groups, the likelihood of developing CAD increased exponentially with each additional risk factor. The probability of CAD was 3, 7, and 24 times higher with 1, 2, and 3 or more risk factors, respectively.

To read more: https://www.sciencedaily.com/releases/2019/09/190902181602.htm