From a New England Journal of Medicine online release:
In humans, intermittent-fasting interventions ameliorate obesity, insulin resistance, dyslipidemia, hypertension, and inflammation. Intermittent fasting seems to confer health benefits to a greater extent than can be attributed just to a reduction in caloric intake.
Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-based energy, with increased stress resistance, increased longevity, and a decreased incidence of diseases, including cancer and obesity.
Preclinical studies and clinical trials have shown that intermittent fasting has broad-spectrum benefits for many health conditions, such as obesity, diabetes mellitus, cardiovascular disease, cancers, and neurologic disorders. Animal models show that intermittent fasting improves health throughout the life span, whereas clinical studies have mainly involved relatively short-term interventions, over a period of months.
BOOMERS-DAILY.COM “18-HOUR INTERMITTENT FASTING DIET” STUDY
How much of the benefit of intermittent fasting is due to metabolic switching and how much is due to weight loss? Many studies have indicated that several of the benefits of intermittent fasting are dissociated from its effects on weight loss. These benefits include improvements in glucose regulation, blood pressure, and heart rate; the efficacy of endurance training; and abdominal fat loss.
‘Successful Aging’ uses research from developmental neuroscience and the psychology of individual differences to show that sixty-plus years is a unique developmental stage that, like infancy or adolescence, has its own demands and distinct advantages. Levitin looks at the science behind what we all can learn from those who age joyously, as well as how to adapt our culture to take full advantage of older people’s wisdom and experience. Throughout his exploration of what aging really means, Levitin reveals resilience strategies and practical, cognitive enhancing tricks everyone should do as they age.
When the five sleep factors were collapsed into binary categories of low risk vs. high risk (reference group), early chronotype, adequate sleep duration, free of insomnia, and no frequent daytime sleepiness were each independently associated with incident CVD, with a 7%, 12%, 8%, and 15% lower risk, respectively (Table 
Cardiovascular disease (CVD), including coronary heart disease (CHD) and stroke, is among the leading causes of mortality globally.
During this decade, as in previous decades, Caltech scientists and engineers reinvented the landscape of scientific endeavor: from the first detection of gravitational waves and the discovery of evidence for a ninth planet in the solar system; to bold missions to explore and understand the solar system; to the development of new methods to see inside the body and the brain and understand the universe around us; to the invention of devices to improve human health, some taking inspiration from nature; to the initiation of a transformative new effort to support research into the most pressing challenges in environmental sustainability.
Though the brain orchestrates how we experience the world, many questions remain about its complex workings. During the past 10 years, Caltech scientists have discovered how the brain recognizes 
As modern technology advances, so do the possibilities for treating medical conditions that were previously considered untreatable. Caltech researchers used an electrode array to help a paralyzed patient 
In our own study of more than 7,000 middle-aged to older adults in the U.K., published in 2019 in Brain Imaging and Behavior, we demonstrated that people who spent more time engaged in moderate to vigorous physical activity had larger hippocampal volumes. Although it is not yet possible to say whether these effects in humans are related to neurogenesis or other forms of brain plasticity, such as increasing connections among existing neurons, together the results clearly indicate that exercise can benefit the brain’s hippocampus and its cognitive functions.
Boomers Daily 