




Published online by Cambridge University Press: 22 March 2021
As we age, there are characteristic changes in our thinking, reasoning and memory skills (referred to as cognitive ageing). However, variation between people in the timing and degree of change experienced suggests that a range of factors determine individual cognitive ageing trajectories. This narrative review considers some of the lifestyle factors that might promote (or harm) cognitive health. The focus on lifestyle factors is because these are potentially modifiable by individuals or may be the targets of behavioural or societal interventions. To support that, the review briefly considers people’s beliefs and attitudes about cognitive ageing; the nature and timing of cognitive changes across the lifespan; and the genetic contributions to cognitive ability level and change. In introducing potentially modifiable determinants, a framing that draws evidence derived from epidemiological studies of dementia is provided, before an overview of lifestyle and behavioural predictors of cognitive health, including education and occupation, diet and activity.

People today want to be more in control of their own health and are more attuned to getting the support and information they need online, from apps, and from connected products. Yet there are gaps in both their knowledge and daily commitment to good oral hygiene, and they need help along the way. Depending on lifestage, patient’s oral health concerns can evolve from plaque removal and aesthetics to larger concerns around gum health and disease. Too often, by the time they begin thinking about gum health, it’s too late. Multiple studies have revealed linkages between periodontal diseases and certain systemic diseases, such as diabetes, heart disease and kidney disease [4][5][6].
Prevention is key. Along with professional deep cleaning, good daily brushing and interdental cleaning are critical. It’s also important for patients to have regular conversations with their dentist about oral health issues and the linkage to their overall health.

Some firms are developing their own vaccines against Covid-19, while others are aiming to reformulate some of the dozens already in development or being rolled out world-wide. Some are sitting this pandemic out in the hope of being ready for the next one.
All are in the early to mid-stages of development and clinical testing, suggesting it might be months if not years before they come to market. Big pharmaceutical companies have so far shown limited interest.



Eight different Covid-19 vaccines are currently being used around the world and just over 172 million people have received their first dose, 2.2 for every 100 people. All of the vaccines being used require two shots but that is set to change with Johnson & Johnson’s JNJ+0.3%JNJ+0.3% one-shot vaccine expected to gain regulatory approval for use in the United States within weeks. As it stands, the first Covid-19 vaccine to be authorized for use in the U.S. is also the most widely used shot globally, according to information from website Our World in Data reported by The New York Times.


Currently, smartwatches provide information such as heart rate, sleep time and activity patterns. In the future, this could be augmented with new classes of wearable devices that monitor, for example, concentrations of cortisol for tracking stress (using electronic epidermal tattoos), biomarkers of inflammation and levels of blood O2 (microneedle patches), skin temperature (electronic textiles), blood pressure (smart rings), concentration of ions (wristbands), intraocular pressure (smart contact lenses), the presence of airborne pathogens and breathing anomalies (face masks), and the concentration of therapeutic drugs (on-teeth sensors)2,10,12,13,14,15,16. Such emerging low-cost wearable sensing technologies, monitoring both physical parameters and biochemical markers, could be used to identify symptomatic and pre-symptomatic cases in future pandemics. The devices could also be used to remotely monitor the recovery of individuals undergoing treatment or self-isolating at home.