Tag Archives: Kidney Disease

Medicine: Kidney Disease Explained (Mayo Clinic)

Chronic kidney disease, also called chronic kidney failure, involves a gradual loss of kidney function. Your kidneys filter wastes and excess fluids from your blood, which are then removed in your urine. Advanced chronic kidney disease can cause dangerous levels of fluid, electrolytes and wastes to build up in your body.

Video timeline:  0:31 What is kidney disease?  1:09 Who gets kidney disease/risk factors?   2:24 Kidney disease symptoms 3:03 How is kidney disease diagnosed? 3:53 Treatment options   5:23 Coping methods/ What now?  6:16 Ending    

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Infographic: Poor Oral Health Leads To Chronic And Systemic Disease

Good oral health leads to benefits beyond a healthy mouth

People today want to be more in control of their own health and are more attuned to getting the support and information they need online, from apps, and from connected products. Yet there are gaps in both their knowledge and daily commitment to good oral hygiene, and they need help along the way. Depending on lifestage, patient’s oral health concerns can evolve from plaque removal and aesthetics to larger concerns around gum health and disease. Too often, by the time they begin thinking about gum health, it’s too late. Multiple studies have revealed linkages between periodontal diseases and certain systemic diseases, such as diabetesheart disease and kidney disease [4][5][6].

Prevention is key. Along with professional deep cleaning, good daily brushing and interdental cleaning are critical. It’s also important for patients to have regular conversations with their dentist about oral health issues and the linkage to their overall health.

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Health: ‘Diabetes And Chronic Kidney Disease’ – New Guidelines (OCt 2020)

Comprehensive care in patients with diabetes and CKD

Management of CKD in diabetes can be challenging and complex, and a multidisciplinary team should be involved (doctors, nurses, dietitians, educators, etc). Patient participation is important for self-management and to participate in shared decision-making regarding the management plan. (Practice point).

We recommend that treatment with an angiotensin-converting enzyme inhibitor (ACEi) or an angiotensin II receptor blocker (ARB) be initiated in patients with diabetes, hypertension, and albuminuria, and that these medications be titrated to the highest approved dose that is tolerated (1B).

Lifestyle interventions in patients with diabetes and CKD

We suggest maintaining a protein intake of 0.8 g protein/kg)/d for those with diabetes and CKD not treated with dialysis (2C).

On the amount of proteins recommended in these guidelines, they suggest (‘recommend’ becomes a ‘suggest’ at this level of evidence) a very precise  intake of 0.8g/kg/d in patients with diabetes and CKD. Lower dietary protein intake has been hypothesized but never proven to reduce glomerular hyperfiltration and slow progression of CKD, however in patients with diabetes, limiting protein intake below 0.8g/kg/d can be translated into a decreased caloric content, significant weight loss and quality of life. Malnutrition from protein and calorie deficit is possible.

Physical activity

We recommend that patients with diabetes and CKD be advised to undertake moderate-intensity physical activity for a cumulative duration of at least 150 minutes per week, or to a level compatible with their cardiovascular and physical tolerance (1D).

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Digital Medicine: Apps For Smartphones, Machine Learning To Treat Kidney Disease (The Lancet)

From a The Lancet online article (January 18, 2020):

The Lancet logoSmartphone app-based platforms for urine testing could improve adherence to albumin creatinine ratio (ACR) testing. One study showed screening of at-risk patients almost doubled with a home urine test kit that uses a smartphone camera to easily and accurately quantify ACR from a user-performed urine dipstick. If independently validated in a large, diverse population, this low-cost strategy could change the often dim trajectory for individuals with declining kidney function. Chronic Kidney Disease A Global Crisis Siemens Healthineers

In the outpatient setting, a Japanese team used machine learning and natural language processing to predict disease progression and need for dialysis over 6 months in patients with diabetic nephropathy. And while the increased risk of contrast-induced acute kidney injury has been long appreciated, a machine learning algorithm trained and tested on 3 million adults effectively quantified the degree of kidney injury on the basis of the volume of contrast used and individual patient-level characteristics.

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Health Studies: Patients With Gout Face Double The Risk Of Kidney Failure

From a  Eurekalert.org online release:

Gout Study - Increased Kidney Failure Risk UL“While we always believed that high levels of uric acid might be bad for kidneys and that patients with gout may have a higher risk of kidney failure, we were quite surprised by the magnitude of the risk imposed by gout in these patients. We were particularly interested in the risk of advanced kidney disease, as these patients in general have a higher risk of kidney failure and death.

Patients with gout are at increased risk of chronic kidney disease and kidney failure, according to new University of Limerick (UL), Ireland led research.

In one of the largest and most detailed studies ever conducted, patients recruited in general practice with a diagnosis of gout were more than twice as likely to develop kidney failure than those without, according to the study led by researchers at University of Limerick’s (UL) Graduate Entry Medical School (GEMS).