Living With Hypertension: Reduced Brain Size And Increased Dementia Risks

Treating Depression: Deep Brain Stimulation (UCSF)

UCSF Health physicians have successfully treated a patient with severe depression by tapping into the specific brain circuit involved in depressive brain patterns and resetting them using the equivalent of a pacemaker for the brain.

Analysis: China’s New Reality, London Stock Market, Ford & GM EV’s

A selection of three essential articles read aloud from the latest issue of The Economist. This week: Xi Jinping’s campaign against China’s capitalist excesses, how to revive Britain’s stockmarket (10:11), and electric motor city (18:33).

Science Of The Brain: What Is Interoception? (Scripps)

Your brain is keenly aware of what’s going on inside your body at all times. Some things are obvious – like when you feel hungry or thirsty. But some things you never notice – like how blood vessels all over your body simultaneously contract as you stand up, so you don’t lose blood flow to your brain. But how does your brain know when to send the signal to squeeze? It’s all part of concept scientists call interoception – the dialogue between your brain and the rest of your body.

Interoception is involved in everything from keeping us balanced while we walk, to keeping our blood pressure and heart rate steady. It even appears to influence our moods and emotions. And thanks to recent discoveries, we’re learning more about how interoception works. Researchers identified two special channels in neurons that react to touch and named them PIEZO1 and PIEZO2. Since first identifying these pressure sensors, researchers have found PIEZOs in internal organs like the heart, lungs, and blood vessels lining the stomach… suggesting many physiological functions involve mechanical forces that our brain and other parts of our nervous system must monitor and influence. As the study of interoception grows, scientists are hopeful the field could lead to breakthroughs in treating heart disease, controlling blood pressure, relieving anxiety and depression, and treating a number of other disorders. Learn more about Scripps Research at scripps.edu.

Guided Tour Travel: Nashville, Tennessee

Nashville is the capital of the U.S. state of Tennessee and home to Vanderbilt University. Legendary country music venues include the Grand Ole Opry House, home of the famous “Grand Ole Opry” stage and radio show. The Country Music Hall of Fame and Museum and historic Ryman Auditorium are Downtown, as is the District, featuring honky-tonks with live music and the Johnny Cash Museum, celebrating the singer’s life. 

Covid-19: ‘The Variant Hunters’ – Understanding Its Spread (Cambridge)

The variant hunters are helping us to understand how and why the COVID-19 virus is spreading, allowing us to fight back against the COVID-19 pandemic.

Hear from some of the scientists behind the UK’s nationwide sequencing effort to track SARS-CoV-2. Sir Patrick Vallance (the government’s Chief Scientific Adviser) also describes how the expertise that came together during the pandemic is now recognised across the world – and why it’s crucially important to continue to sequence to be ready for future pandemics.

This pioneering work is being carried out by the COVID-19 Genomics UK (COG-UK) consortium, which comprises numerous academic institutions, four public health agencies and the Wellcome Sanger Institute, and is administered by the University of Cambridge.

“Incredibly impressive, incredibly high quality and incredibly focused on the mission to make sure that as many people benefited from the science as possible,” Sir Patrick Vallance.

Read more: https://www.cam.ac.uk/stories/variant…