Molnupiravir (MK-4482, EIDD-2801) is an investigational oral antiviral medicine that significantly reduced the risk of hospitalization or death at a planned interim analysis of the Phase 3 MOVe-OUT trial in at risk, non-hospitalized adult patients with mild-to-moderate COVID-19. At the interim analysis, molnupiravir reduced the risk of hospitalization or death by approximately 50%; 7.3% of patients who received molnupiravir were either hospitalized or died through Day 29 following randomization (28/385), compared with 14.1% of placebo-treated patients (53/377); p=0.0012. Through Day 29, no deaths were reported in patients who received molnupiravir, as compared to 8 deaths in patients who received placebo.
Dhaka is the capital city of Bangladesh, in southern Asia. Set beside the Buriganga River, it’s at the center of national government, trade and culture. The 17th-century old city was the Mughal capital of Bengal, and many palaces and mosques remain. American architect Louis Khan’s National Parliament House complex typifies the huge, fast-growing modern metropolis.
Hitch a ride with 60 Minutes correspondent Bill Whitaker along the Green River Drift, the longest running cattle drive in the U.S.
Upper Green River Valley, Wyoming
Predating most federal land management agencies, the Green River Drift cattle trail has been continuously used since the 1890s by the Upper Green River Cattle Association ranchers to get cattle from spring pasture on the desert to summer pasture in the forest. Chilly fall weather causes the cattle to “drift” back out of the forest to return to their home ranches. The trail, 58 miles long with 41 miles of spurs, crosses BLM, State of Wyoming, National Forest, and private properties.
Grodno is a city in western Belarus, near the Polish and Lithuanian borders. By the Neman River, the Old Castle is a Renaissance palace on the site of an 11th-century fort. Nearby, the New Castle was built in the 18th century as a royal residence. The 12th-century Kalozha Church of Sts. Boris and Gleb is adorned with polished stones and majolica tiles. The St. Francis Xavier Cathedral features an ornate carved altar.
A selection of three essential articles read aloud from the latest issue of The Economist. This week, the first big energy shock of the green era, how covid-19 will move from pandemic to endemic (11:29) and our Charlemagne columnist assesses the odds of “Polexit” versus a “dirty remain” (17:21).