On this week’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to talk about a Science paper that combines two hot areas of research—CRISPR gene editing and immunotherapy for cancer—and tests it in patients.
Sarah also talks with Damien Finch, a Ph.D. candidate in the School of Earth Sciences at the University of Melbourne, about the Kimberly region of Australia and dating its ice age cave paintings using charcoal from nearby wasp nests.
Structural biologists rejoiced when cryo–electron microscopy, a technique to generate highly detailed models of biomolecules, emerged. But years after its release, researchers still face long queues to access these machines. Science’s European News Editor Eric Hand walks host Meagan Cantwell through the journey of a group of researchers to create a cheaper, more accessible alternative.
Also this week, host Joel Goldberg speaks with psychiatrist and researcher Goodman Sibeko, who worked with the Xhosa people of South Africa to help illuminate genetic details of schizophrenia. Though scientists have examined this subject among Western populations, much less is known about the underlying genetics of people native to Africa.
Though a law requiring clinical trial results reporting has been on the books for decades, many researchers have been slow to comply. Now, 2 years after the law was sharpened with higher penalties for noncompliance, investigative correspondent Charles Piller took a look at the results. He talks with host Sarah Crespi about the investigation and a surprising lack of compliance and enforcement.
Also this week, Sarah talks with Brett Finlay, a microbiologist at the University Of British Columbia, Vancouver, about an Insight in this week’s issue that aims to connect the dots between noncommunicable diseases like heart disease, diabetes, and cancer and the microbes that live in our guts. Could these diseases actually spread through our microbiomes?
Getting into an MRI machine can be a tight fit for just one person. Now, researchers interested in studying face-to-face interactions are attempting to squeeze a whole other person into the same tube, while taking functional MRI (fMRI) measurements. Staff Writer Kelly Servick joins host Sarah Crespi to talk about the kinds of questions simultaneous fMRIs might answer.
Also this week, Sarah talks with Igor Grossman, director of the Wisdom and Culture Lab at the University of Waterloo, about his group’s Science Advances paper on public perceptions of the difference between something being rational and something being reasonable.
We start our first episode of the new year looking at future trends in policy and research with host Joel Goldberg and several Science News writers. Jeffrey Mervis discusses upcoming policy changes, Kelly Servick gives a rundown of areas to watch in the life sciences, and Ann Gibbons talks about potential advances in ancient proteins and DNA.
In research news, host Meagan Cantwell talks with Beatriz Pinto-Goncalves, a postdoctoral researcher at the John Innes Centre, about carnivorous plant traps. Through understanding the mechanisms that create these traps, Pinto-Goncalves and colleagues elucidate what this could mean for how they emerged in the evolutionary history of plants.
As the year comes to a close, we review the best science, the best stories, and the best books from 2019. Our end-of-the-year episode kicks off with Host Sarah Crespi and Online News Editor David Grimm talking about the top online stories on things like human self-domestication, the “wood wide web,” and more.
News Editor Tim Appenzeller joins Sarah to discuss Science’s 2019 Breakthrough of the Year, some of the contenders for breakthrough, also known as runners-up, and a breakdown—when science and politics just didn’t seem to mix this year.
Finally, Science books editor Valerie Thompson brings her favorites from the world of science-inflected media. She and Sarah talk about some of the best books reviewed in Science this year, a food extinction book we should have reviewed, a pair of science-centric films, and even an award-winning birding board game.
About one-third of people with epilepsy are treatment resistant. Up until now, epilepsy treatments have focused on taming seizures rather than the source of the disease and for good reason—so many roads lead to epilepsy: traumatic brain injury, extreme fever and infection, and genetic disorders, to name a few. Staff Writer Jennifer Couzin-Frankel talks with host Sarah Crespi about researchers that are turning back the pages on epilepsy, trying to get to the beginning of the story where new treatments might work.
And Sarah also talks with Torsten Neurbert at the Technical University of Denmark’s National Space Institute in Kongens Lyngby about capturing high-altitude “transient luminous events” from the International Space Station (ISS). These lightning-induced bursts of light, color, and occasionally gamma rays were first reported in the 1990s but had only been recorded from the ground or aircraft. With new measurements from the ISS come new insights into the anatomy of lightning.
Website: https://www.sciencemag.org/podcast/hunting-new-epilepsy-drugs-and-capturing-lightning-space
From a Science Magazine online article:
On 13 December, Amazon Prime will air the fourth season of The Expanse, a hardboiled space drama renowned for its working-class characters and real-world space physics. Showrunner Naren Shankar is part of the reason the science checks out. The veteran writer and producer for programs such as Star Trek: The Next Generation, Farscape, and the police procedural CSI: Crime Scene Investigation, has a doctorate in applied physics and electrical engineering.
Shankar chatted with Science about why he feels it’s important to have a realistic sci-fi show, and how television work is like the scientific peer-review process.
To read full interview: https://www.sciencemag.org/news/2019/12/how-real-world-science-sets-expanse-apart-other-sci-fi-shows?utm_campaign=news_weekly_2019-12-06&et_rid=600792821&et_cid=3113276
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