This week’s cover, “Beasts and Beauties,” by Edward Steed. #NewYorkerCovers https://t.co/SnRUDwgMvX pic.twitter.com/vj1ZhEBEoE
— The New Yorker (@NewYorker) October 18, 2021
Tag Archives: Reviews
Covid-19: Molnupiravir – Merck’s Antiviral Drug
Molnupiravir (MK-4482, EIDD-2801) is an investigational oral antiviral medicine that significantly reduced the risk of hospitalization or death at a planned interim analysis of the Phase 3 MOVe-OUT trial in at risk, non-hospitalized adult patients with mild-to-moderate COVID-19. At the interim analysis, molnupiravir reduced the risk of hospitalization or death by approximately 50%; 7.3% of patients who received molnupiravir were either hospitalized or died through Day 29 following randomization (28/385), compared with 14.1% of placebo-treated patients (53/377); p=0.0012. Through Day 29, no deaths were reported in patients who received molnupiravir, as compared to 8 deaths in patients who received placebo.
Science: Ripple Effects Of Mass Incarceration, Dog-Sniff Evidence Reliability
This week we are covering the Science special issue on mass incarceration. Can a dog find a body? Sometimes. Can a dog indicate a body was in a spot a few months ago, even though it’s not there now?
There’s not much scientific evidence to back up such claims. But in the United States, people are being sent to prison based on this type of evidence. Host Sarah Crespi talks with Peter Andrey Smith, a reporter and researcher based in Maine, about the science—or lack thereof—behind dog-sniff evidence.
With 2 million people in jail or prison in the United States, it has become incredibly common to have a close relative behind bars. Sarah talks with Hedwig Lee, a sociologist at Washington University in St. Louis, about the consequences of mass incarceration for families of the incarcerated, from economic to social.
Front Covers: Nature Magazine – October 14
Science: Accupuncture’s Inflammation Effect, Antibiotics & Gut Bacteria
The neurons behind acupuncture’s effect on inflammation, and how antibiotics affect gut bacteria.
In this episode:
00:54 The neuronal basis for acupuncture’s effect on inflammation
In mice, electroacupuncture has been shown to reduce inflammation, but only when certain points on the body are stimulated. Why this is has puzzled scientists, but now, researchers have identified the specific neurons that are involved. They hope that this knowledge could be used in future to help treat certain inflammatory-related diseases.
Research article: Liu et al.
News and Views: Electroacupuncture activates neurons to switch off inflammation
07:28 Research Highlights
The Aztec origins of an obsidian ‘spirit mirror’, and the damage done by a Soviet plutonium complex.
Research Highlight: A ‘spirit mirror’ used in Elizabeth I’s court had Aztec roots
Research Highlight: Cold-war spy pictures reveal a Soviet nuclear ‘cloud generator’
10:18 Assessing antibiotics’ collateral damage.
Antibiotics are known to cause damage to the communities of bacteria that live in our guts. To better understand why this happens, a team has mapped the effects that different antibiotics have on individual gut-bacteria species, which may offer new insights into preventing this collateral damage.
Research article: Maier et al.
17:32 Briefing Chat
We discuss some highlights from the Nature Briefing. This time, the latest species to be declared extinct in the US, and a potential planet that orbits three stars.
New York Times: Protected Too Late: U.S. Officials Report More Than 20 Extinctions
New York Times: This May Be the First Planet Found Orbiting 3 Stars at Once
Front Covers: Science Magazine – October 8
Cremation Diamonds: An Afterlife After Death
Front Covers: Nature Magazine – September 30
Previews: New Scientist Magazine – October 2
Science: Whole-Genome Screening For Newborns, Active Learning For STEM
Today, most newborns get some biochemical screens of their blood, but whole-genome sequencing is a much more comprehensive look at an infant—maybe too comprehensive?
Staff Writer Jocelyn Kaiser joins host Sarah Crespi to discuss the ethical ins and outs of whole-genome screening for newborns, and the kinds of infrastructure needed to use these screens more widely. Sarah also talks with three contributors to a series of vignettes on the importance of active learning for students in science, technology, engineering, and math. Yuko Munakata, professor in the department of psychology and Center for Mind and Brain at the University of California, Davis, talks about how the amount of unstructured time and active learning contributes to developing executive function—the way our brains keep us on task. Nesra Yannier, special faculty at Carnegie Mellon University and inventor of NoRILLA, discusses an artificial intelligence–driven learning platform that helps children explore and learn about the real world. Finally, Louis Deslauriers, senior preceptor in the department of physics and director of science teaching and learning at Harvard University, laments lectures: why we like them so much, why we think we learn more from lectures than inquiry-based learning, and why we’re wrong.
Boomers Daily 