The all-electric First Ever GMC HUMMER EV leads a quiet revolution – with zero emissions and zero limits. It earns its super truck status with up to:From a Technology Networks online article:
By comparing the pancreatic cells of type 2 diabetic human donors with those of healthy people, researchers at the University of Geneva (UNIGE) and at the University Hospitals of Geneva (HUG), Switzerland, were able to demonstrate, for the first time, that the pancreatic islet cells derived from the Type 2 Diabetic human donors bear compromised circadian oscillators.
The disruption of the circadian clocks was concomitant with the perturbation of hormone secretion. Moreover, using clock modulator molecule dubbed Nobiletin, extracted from lemon peel, the researchers succeeded in “repairing” the disrupted cellular clocks and in partial restoring of the islet cell function. These results, published in the Proceedings of the National Academy of Sciences of the United States, provide a first insight into innovative approach for diabetes care.
The circadian clock system (from Latin “circa diem”, about a day) allows the organisms to anticipate periodical changes of geophysical time, and to adjust to these changes. Nearly all the cells in our body comprise molecular clocks that regulate and synchronize metabolic functions to a 24-hour cycle of day-night changes.
Today, increasing evidence show that disturbances in our internal clocks stemming from frequent time zone changes, irregular working schedules or ageing, have a significant impact on the development of metabolic diseases in human beings, including type-2 diabetes. Such disturbances seem to prevent the proper functioning of the cells in the pancreatic islet that secrete insulin and glucagon, the hormones that regulate blood sugar levels.
Dozens of new electric-vehicle models are expected to arrive at dealerships in the next few years. We followed eight Wall Street Journal reporters in four countries to see if they, and the world, are ready to make the switch.
PBS NewsHour co-founder Jim Lehrer, a giant in journalism known for his tenacity and dedication to simply delivering the news, died peacefully in his sleep at home on Thursday, at the age of 85.
The Guardian’s health editor, Sarah Boseley, answers some of the most common and pressing questions surrounding the recent coronavirus outbreak in Wuhan, China
From an Undark.org online article:
This subsidence means that in a low-lying nation famous for engineering its way around rising seas, the ground is also sinking lower, creating huge problems for the structures built on top. At a certain point, building foundations begin to crack, sinkholes appear, roads destabilize, and the risk of flooding increases. More construction results in more pressing down of the peat — and more subsidence.
TOURISTS VISITING the Netherlands often stop to take selfies in front of one of the country’s more than 1,000 windmills. Afterward, they might taste one of the many varieties of cheese for which the nation is famous. But most are unaware that these two icons of the Netherlands are responsible for causing the nation’s land to sink.
The windmills were used for centuries to drain peatland for cattle grazing and agriculture at large, and that draining — these days done by pumping stations — is causing the land in some places to sink at an average rate of 8 millimeters per year, or about one-third of an inch. (In some areas, researchers put that number higher, at several centimeters per year.)
From a Hollywood Reporter online release:
“Turman, Nichols and I related to The Graduate in exactly the same way,” Henry told Vanity Fair. “We all thought we were [the book’s protagonist] Benjamin Braddock. Plus, it’s an absolutely first-class novel, with great characters, great dialogue, a terrific theme. Who could resist it? I read it and I said, ‘Yes, let’s go.'”
Henry landed his first Oscar nom for the screenplay (he came up with the word “plastics” and had a small role in the film) and received a second nom for co-directing (with Warren Beatty) the reincarnation comedy Heaven Can Wait, a remake of the 1941 film Here Comes Mr. Jordan.
Buck Henry, the impish screenwriter whose wry, satirical sensibility brought comic electricity to The Graduate, What’s Up, Doc?, To Die For and TV’s Get Smart, has died. He was 89.
Henry, a two-time Oscar nominee who often appeared onscreen — perhaps most memorably as a 10-time host (all in the show’s first four years) on Saturday Night Live — died of a heart attack Wednesday at a Los Angeles hospital, his wife, Irene, told The Washington Post. He had suffered a stroke in November 2014.
David Remnick has appeared as the guest of Terry Gross on “Fresh Air” a number of times over the years, talking about Russia, Muhammad Ali, and other subjects. Hosting “Fresh Air” for nearly forty-five years, Gross is a defining voice of NPR, and is perhaps the most celebrated interviewer of our time.
In October, 2019, the tables turned, and Gross joined Remnick as his guest for a live interview at The New Yorker Festival. They spoke about how she first found her way to the microphone, the role of feminism in establishing NPR, the limits of her expertise, and what she has had to give up to prepare for serious conversations day after day.
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