Tag Archives: Medicine

Eye Health: The Causes Of Nearsightedness (Myopia)

Cleveland Clinic – Nearly 1 out of 3 people have a vision disorder called myopia, or nearsightedness, which makes it difficult to view things in the distance. How does it happen? And is there a cure?

Chapters: 0:00 Intro 0:32 What causes nearsightedness? 1:01 Why can’t you see far? 1:20 When does nearsightedness usually begin? 1:42 What are symptoms of nearsightedness? 1:59 Can nearsightedness be corrected? 2:23 Is there a cure for nearsightedness?

What is myopia?

People who have myopia (also known as nearsightedness) have difficulty seeing distant objects, but can see objects that are near clearly. For example, a person who is nearsighted may not be able to make out highway signs until they are just a few feet away.

Myopia affects a significant percentage of the population. It’s an eye focus disorder that is easily corrected with eyeglasses, contact lenses or surgery.

How common is myopia?

Myopia is very common. According to the American Optometric Association, more than 40% of Americans are myopic, a number that is rapidly rising, especially among school-aged children. Eye experts expect this trend to continue in the coming decades.

Today one in four parents has a child with some degree of nearsightedness. Some eye experts believe that if your child spends an extraordinary amount of time engaged in “near” activities, such as reading or using smartphones and computers, it may raise the risk of developing myopia.

Can myopia lead to blindness?

Usually, myopia is a minor nuisance that can be corrected with eyeglasses, contact lenses or surgery. But in rare cases, a progressive type called degenerative myopia develops that can be very serious and is a leading cause of legal blindness. Degenerative myopia affects only about 2% of the population. It is believed to be inherited and is more common in Jewish, Japanese, Chinese and Middle Eastern people.

Read more

Aging: ‘Healthy Longevity’ Journal – November 2022

Image

Inside the November 2022 Issue:

Research & review on #Alzheimers, global burden of benign prostatic hyperplasia, #WHO def of vitality capacity, IPD meta on social connection &  #cognition#oralhealth for older people & more.


Hope on the horizon for Alzheimer’s disease treatment?

Social connectedness and cognitive decline

Time to take oral health seriously

HEALTH: HOW CHRONIC KIDNEY DISEASE, DIABETES & HEART DISEASE ARE LINKED

Centers for Disease Control and Prevention (CDC) – The body is complicated! While organs in your body each have a specific job to do to keep you healthy, they still rely on each other to function well. When one organ isn’t working the way it should, it can put stress on other organs, causing them to stop working properly as well.

The relationship between chronic kidney disease (CKD), diabetes, and heart disease is one example of the ways our organs are connected.

The body uses a hormone called insulin to get blood sugar into the body’s cells to be used as energy. If someone has diabetes, their pancreas either doesn’t make enough insulin or can’t use the insulin it makes as well as it should.

If someone has CKD, their kidneys are not able to filter out toxins and waste from their blood as well as they should.

Heart disease refers to several types of heart conditions. The most common condition, coronary artery disease, leads to changes in blood flow to the heart, which can cause a heart attack.

Make the Connection

So how are these three conditions connected? Risk factors for each condition are similar and include high blood sugar, high blood pressure, family history, obesity, unhealthy diet, and physical inactivity.

High blood sugar can slowly damage the kidneys, and, over time, they can stop filtering blood as well as they should, leading to CKD. Approximately 1 in 3 adults with diabetes has CKD.

When the kidneys don’t work well, more stress is put on the heart. When someone has CKD, their heart needs to pump harder to get blood to the kidneys. This can lead to heart disease, the leading cause of death in the United States. Change in blood pressure is also a CKD complication that can lead to heart disease.

Luckily, preventing or managing one condition can help you prevent and manage the others and lower the risk for more complications.

EYE HEALTH: THE SIGNS AND DIAGNOSIS OF CATARACTS

Cleveland Clinic – Cataracts in the eye lens are a later-in-life reality that leads to vision problems for many people. This video shares describes what cataracts are, how they form, and warning signs to help you detect them early.

Chapters: 0:00 Intro 0:10 What are cataracts? 0:43 What are the warning signs of cataracts? 2:44 How are cataracts diagnosed? 3:04 Talk to your eye doctor

Aging: How Regenerative Medicine Slows The Clock

“Diverse aging populations, vulnerable to chronic disease, are at the cusp of a promising future. Indeed, growing regenerative options offer opportunities to boost innate healing, and address aging-associated decline. The outlook for an extended well-being strives to achieve health for all,”

Andre Terzic, M.D., Ph.D., a Mayo Clinic cardiologist

Regenerative medicine could slow the clock on degenerative diseases that often ravage the golden years, a Mayo Clinic study finds. Life span has nearly doubled since the 1950s, but health span — the number of disease-free years — has not kept pace. According to a paper published in NPJ Regenerative Medicine., people are generally living longer, but the last decade of life is often racked with chronic, age-related diseases that diminish quality of life. These final years come with a great cost burden to society.

Researchers contend that new solutions for increasing health span lie at the intersection of regenerative medicine research, anti-senescent investigation, clinical care and societal supports. A regenerative approach offers hope of extending the longevity of good health, so a person’s final years can be lived to the fullest.

Read more

Health: American Heart Association Updates Its ‘Optimal Checklist’ (2022)

October 2022 – The American Heart Association (AHA) recently revised its checklist for achieving optimal heart health, introducing its new Life’s Essential 8. The list replaces the AHA’s decade-old Life’s Simple 7.

Sleep health is the new addition to the cardiovascular health scoring tool, which now advises that adults get seven to nine hours per night. The organization updated four of the categories:

  • Diet: More emphasis was given to following heart-healthy diets like the DASH and Mediterranean.
  • Nicotine exposure: Secondhand smoke and vaping were added as risk factors.
  • Blood lipids: People now can get a non-fasting blood sample that measures total, HDL, and non-HDL cholesterol. Non-HDL cholesterol can provide similar risk information as LDL cholesterol.
  • Blood sugar: Measurements now include hemoglobin A1c, a key component to assessing type 2 diabetes risk.
  • Three categories were unchanged:
  • Physical activity: The optimal weekly level is at least 150 minutes of moderate activity or 75 minutes of vigorous activity.
  • Body mass index (BMI): A BMI of 18.5 to 24.9 is ideal for heart health.
  • Blood pressure: Levels less than 120/80 millimeters of mercury (mm Hg) remain optimal. Stage 1 hypertension is 130 to 139 mm Hg for systolic pressure (the first number) or 80 to 89 mm Hg for diastolic pressure (the second number).
  • You can calculate your heart health score at mlc.heart.org. The guidelines were published online June 29, 2022, by Circulation.

Read more

Health: Nature Medicine Magazine – October 2022

Volume 28 Issue 10

Association of step counts over time with the risk of chronic disease in the All of Us Research Program

Using electronic health records data from the All of Us Research Program, we show that higher daily step counts in data collected over several years of Fitbit fitness tracker use were associated with lower risk of common, chronic diseases, including diabetes, hypertension, gastroesophageal reflux disease, depression, obesity and sleep apnea.

Meat, vegetables and health — interpreting the evidence

Although questions remain about several diet and disease associations, current evidence supports dietary guidelines to limit red meat and increase vegetable intake.

CRISPR–Cas9 hits its target in amyloidosis

Nature Medicine explores the latest translational and clinical research news, with an analysis of Intellia and Regeneron’s gene-editing treatment, which reduced levels of transthyretin in patients.

Nature Medicine Website

Science: New Research Into Diseases Of The Brain

Take an animated look inside the neuron, and learn how scientists are addressing brain disease. With approximately 86 billion neurons in the brain, humans contain the most complex communications network imaginable. To address diseases of brain development and degeneration, neuroscientists are investigating how and why this network breaks down, and what can be done to repair it.

One area of study is dendrites, which are the tree-like structures of neurons, that receive electrical impulses. Researchers are carefully mapping out brain circuits and uncovering how connectivity changes can result in defects of the visual system or behavioral problems. The core section of the neuron is the cell body. Genetic engineering tools are revealing how mutations impact brain development and contribute to autism spectrum disorder or rare, inherited forms of neurological disease.

The transmission of nerve impulses occurs along the axon, which is insulated, much like an electrical wire, by a fatty layer called the myelin sheath. Scientists have invented a medicine to stop the immune system from mistakenly attacking this layer, which occurs during multiple sclerosis. Other molecules currently in development instruct the body to regenerate the sheath and repair damage. The axon also transports valuable cellular cargo, such as neurotransmitters, along tracks from one end of the neuron to the other.

Researchers are testing drug candidates for their ability to remove molecular traffic jams when this transport system fails, as often occurs in Parkinson’s and Alzheimer’s disease. The axon terminals make connections called synapses with other cells, using neurotransmitters as signals. Some scientists are evaluating how finely tuning the receptors for these chemicals could ease depression and anxiety.

Others are finding ways to promote the regrowth of lost synapses, which could halt neurodegeneration. From genetics to behavior, neuroscience is accelerating new interventions for the most challenging disorders of the nervous system.

Learn more: https://www.scripps.edu/

Health: Types Of Stroke – Ischemic & Hemorrhagic

There are two types of stroke:

transient ischemic attack (TIA) is sometimes called a “mini-stroke.” It is different from the major types of stroke, because blood flow to the brain is blocked for only a short time—usually no more than 5 minutes.1

Ischemic stroke

Most strokes are ischemic strokes.2 An ischemic stroke occurs when blood clots or other particles block the blood vessels to the brain.

Fatty deposits called plaque can also cause blockages by building up in the blood vessels.

Hemorrhagic stroke

A hemorrhagic stroke happens when an artery in the brain leaks blood or ruptures (breaks open). The leaked blood puts too much pressure on brain cells, which damages them.

High blood pressure and aneurysms—balloon-like bulges in an artery that can stretch and burst—are examples of conditions that can cause a hemorrhagic stroke.

Transient ischemic attack (TIA or “mini-stroke”)

For Blanche Teal-Cruise, a smoker for 40 years who also had high blood pressure, the transient ischemic attack (sometimes called a mini-stroke) she had on the way to work was a wake-up call. Read Blanche’s story.

TIAs are sometimes known as “warning strokes.” It is important to know that

  • A TIA is a warning sign of a future stroke.
  • A TIA is a medical emergency, just like a major stroke.
  • Strokes and TIAs require emergency care. Call 9-1-1 right away if you feel signs of a stroke or see symptoms in someone around you.
  • There is no way to know in the beginning whether symptoms are from a TIA or from a major type of stroke.
  • Like ischemic strokes, blood clots often cause TIAs.
  • More than a third of people who have a TIA and don’t get treatment have a major stroke within 1 year. As many as 10% to 15% of people will have a major stroke within 3 months of a TIA.1

Recognizing and treating TIAs can lower the risk of a major stroke. If you have a TIA, your health care team can find the cause and take steps to prevent a major stroke.

Medicine: Why Long Covid Is Still Not Understood

Even mild COVID-19 is at least correlated with a startlingly wide spectrum of seemingly every illness. We need a much better taxonomy to address people’s suffering.

Long Covid – Whole Body Symptoms

From The Atlantic, October 5, 2022:

The cases of long covid that turn up in news reports, the medical literature, and in the offices of doctors like me fall into a few rough (and sometimes overlapping) categories. The first seems most readily explainable: the combination of organ damage, often profound physical debilitation, and poor mental health inflicted by severe pneumonia and resultant critical illness.

This serious long-term COVID-19 complication gets relatively little media attention despite its severity. The coronavirus can cause acute respiratory distress syndrome, the gravest form of pneumonia, which can in turn provoke a spiral of inflammation and injury that can end up taking down virtually every organ. I have seen many such complications in the ICU: failing hearts, collapsed lungs, failed kidneys, brain hemorrhages, limbs cut off from blood flow, and more. More than 7 million COVID-19 hospitalizations occurred in the United States before the Omicron wave, suggesting that millions could be left with damaged lungs or complications of critical illness. Whether these patients’ needs for care and rehabilitation are being adequately (and equitably) met is unclear: Ensuring that they are is an urgent priority.

Read full article at The Atlantic