From Scientific American (March 1, 2021):
Enter the intranasal vaccine, which abandons the needle and syringe for a spray container that looks more like a nasal decongestant. With a quick spritz up the nose, intranasal vaccines are designed to bolster immune defenses in the mucosa, triggering production of an antibody known as immunoglobulin A, which can block infection. This overwhelming response, called sterilizing immunity, reduces the chance that people will pass on the virus.
The development of highly effective COVID vaccines in less than a year is an extraordinary triumph of science. But several coronavirus variants have emerged that could at least partly evade the immune response induced by the vaccines. These variants should serve as a warning against complacency—and encourage us to explore a different type of vaccination, delivered as a spray in the nose. Intranasal vaccines could provide an additional degree of protection, and help reduce the spread of the virus.
Vaccine science and technology is advancing. Next generation vaccines could change how we combat infectious diseases, and it’s important to understand how the technology works.
In recent decades, the worldwide burden of infectious disease has fallen, thanks to sanitation, hygiene, and prevention and control efforts. But the covid-19 pandemic shows how great a threat to global health remains – particularly as the climate crisis continues to affect disease spread and our response in myriad ways. Increasing temperatures are expanding the areas where diseases such as malaria and dengue thrive. More flooding and drought increases disease risk. Hygiene requires access to clean water. Further urbanization and migration related to climate change will also complicate prevention and control. The BMJ has published “The time is now” collection, calling for the strengthening of the global response to climate change and communicable disease. https://www.bmj.com/communicable-dise…
President Trump’s schedule in the week before he was diagnosed with Covid-19 included a Rose Garden event, a presidential debate, and visits to three states.
Photo: Getty Images
From the Wall Street Journal (June 8, 2020):
“We have to operate a hospital within a hospital, taking care of the needs for patients who have had strokes or a newborn delivery or need surgery while dealing with an otherwise healthy 35-year-old who picked up Covid-19 at a social event,” says James Linder, chief executive of Nebraska Medicine…
For instance, more hospitals are remotely triaging and registering patients before they even arrive. Clinicians can consult with patients from their home via telemedicine to help determine how sick they are and if they need to come to the ER at all. From there, admissions are made with as little contact with staff or other patients as possible.
Hospitals are rethinking how they operate in light of the Covid-19 pandemic—and preparing for a future where such crises may become a grim fact of life.
With the potential for resurgences of the coronavirus, and some scientists warning about outbreaks of other infectious diseases, hospitals don’t want to be caught flat-footed again. So, more of them are turning to new protocols and new technology to overhaul standard operating procedure, from the time patients show up at an emergency room through admission, treatment and discharge.
From web post by Michael B. Edmond (April 11, 2020):
Our goal should be to have a face shield for every person in the country. It should be worn anytime a person leaves their home, while in any public place, and even at work. From news reports, it appears that face shields are already being more commonly worn in other nations, particularly in some Asian countries.
The advantages of face shields are their durability allowing them to be worn an indefinite number of times, the ability to easily clean them after use, their comfort, and they prevent the wearer from touching their face. Importantly, they cover all the portals of entry for this virus–the eyes, the nose, and the mouth. Moreover, the supply chain is significantly more diversified than that of face masks, so availability is much greater.