From a Stanford Medicine online news release:
“What you want is more, small fat cells rather than fewer, large fat cells,” Jackson said. “A large fat cell is not a healthy fat cell. The center is farther away from an oxygen supply, it sends out bad signals and it can burst and release toxic contents.” Large fat cells are associated with insulin resistance, diabetes and inflammation, he added.
Jackson and his colleagues found that when omega-3 fatty acids bind to a receptor called FFAR4 on the cilia of fat stem cells, it prompts the fat stem cells to divide, leading to the creation of more fat cells. This provides the body with more fat cells with which to store energy, something that is healthier than storing too much fat in existing fat cells.
For years, researchers have known that defects in an ancient cellular antenna called the primary cilium are linked with obesity and insulin resistance. Now, researchers at the Stanford University School of Medicine have discovered that the strange little cellular appendage is sensing omega-3 fatty acids in the diet, and that this signal is directly affecting how stem cells in fat tissue divide and turn into fat cells.
To read more: http://med.stanford.edu/news/all-news/2019/11/omega-3-fatty-acids-health-benefit-linked-to-stem-cell-control.html
The purpose of the centers is to increase customers’ understanding of Medicare, match them with people who can talk with them about their benefits or new plans to enroll in, and access in-store annual wellness visits.
Fox has been selling 30-second ads in the event for between “north of $5 million” to as much as $5.6 million, Winter says. In contrast, CBS sought between $5.1 million and $5.3 million for a package of inventory in its 2019 broadcast of the event. Meanwhile, Fox is seeking between $2 million and $3 million for the most expensive advertising slots in its pre- and post-game coverage.
NPR’s Tamara Keith and Amy Walter of the Cook Political Report join Judy Woodruff to discuss the latest political news, including whether two weeks of public impeachment hearings have shifted public opinion about President Trump and the investigation into his Ukraine policy, potential pressure on Republican lawmakers and the late entrance of Michael Bloomberg into the 2020 Democratic race.
Netflix has risen from obscurity to be one of the most powerful media companies in the world with more than 150 million global subscribers. It has launched critically acclaimed hits such as House of Cards, The Crown and Unbelievable, as well as showcasing the back catalogues of popular television series. But as part of its rapid growth, the company has racked up huge debts.
“The link between antibiotic exposure and Parkinson’s disease fits the current view that in a significant proportion of patients the pathology of Parkinson’s may originate in the gut, possibly related to microbial changes, years before the onset of typical Parkinson motor symptoms such as slowness, muscle stiffness and shaking of the extremities. It was known that the bacterial composition of the intestine in Parkinson’s patients is abnormal, but the cause is unclear. Our results suggest that some commonly used antibiotics, which are known to strongly influence the gut microbiota, could be a predisposing factor,” says research team leader, neurologist Filip Scheperjans MD, Ph.D. from the Department of Neurology of Helsinki University Hospital.



Who among us hasn’t wished we could read someone else’s mind, know exactly what they’re thinking? Well that’s impossible, of course, since our thoughts are, more than anything else, our own. Private, personal, unreachable. Or at least that’s what we’ve always, well, thought.
Although he had no pet birds, on closer questioning he had recently acquired a duvet and pillows containing feathers. His symptoms, chest radiograph and lung function tests improved after removal of all feather bedding, and he was also started on oral corticosteroid therapy. Our case reinforces the importance of taking a meticulous exposure history and asking about domestic bedding in patients with unexplained breathlessness. Prompt recognition and cessation of antigen exposure may prevent the development of irreversible lung fibrosis.
