Tag Archives: Health & Medicine

Medical Technology: New Artificial Intelligence (AI) Model Predicts Breast Cancer More Accurately

A new Artificial Intelligence (AI) model predicts breast cancer in mammograms more accurately than radiologists, reducing false positives and false negatives, reports a large international study from Google, Northwestern Medicine and two screening centers in the United Kingdom (U.K.).

 

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https://www.nm.org/

Healthcare: “10 Drugs And Medical Devices Approved By FDA In Dec. 2019 (BHR)

From a Becker’s Hospital Review (BHR) online release article:

10 drugs and medical devices approved by the FDA since Dec. 6:

  1. Enhertu is Japanese drugmaker Daiichi Sankyo’s drug designed to treat HER2-positive breast cancer.
  2. Padcev is Astellas Pharma’s drug designed to target specific cancer cells to treat urothelial cancers.
  3. Control-IQ Technology controller is Tandem Diabetes Care’s insulin device, designed to help diabetes patients tailor their treatments to their individual needs.
  4. Vascepa is Amarin Pharmaceuticals’ drug, a fish oil-derived pill designed to treatVascepa benefits cardiovascular events.
  5. EXALT Model D is Boston Scientific’s device, the first fully disposable duodenoscope, designed to reduce the risk of infections in patients treated with the device.
  6. Vyondys 53 is Sarepta Therapeutics’ drug designed to treat Duchenne muscular dystrophy, which the FDA had previously rejected.
  7. GSP Neonatal Creatine Kinase-MM kit is PerkinElmer’s device, used to detect Duchenne Muscular Dystrophy in newborns.
  8. Unidose liquid system is AptarGroup’s device that uses a nasal spray to treat seizures. It is the first and only nasal treatment for patients with epilepsy.
  9. Avsola is Amgen’s drug, a biosimilar of Johnson & Johnson’s Remicade. It is designed to treat rheumatoid arthritis, Crohn’s disease, plaque psoriasis, psoriatic arthritis and ankylosing spondylitis.
  10. cobas vivoDx is Roche Molecular Systems’ device, designed to diagnose MRSA hours faster than traditional tests.

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To read article at Becker’s Hospital Review

Studies: “Blood-Based ‘Liquid Health Check’ Beats Traditional Predictors of Multiple Disease Risks” (Nature)

From a Genetic Engineering & Biotechnology News release:

Nature Medicine Journal Dec 2019“This proof of concept study demonstrates a new paradigm that measurement of blood proteins can accurately deliver health information that spans across numerous medical specialties and that should be actionable for patients and their healthcare providers,” said Peter Ganz, MD, co-leader of this study and the Maurice Eliaser distinguished professor of medicine at UCSF and director of the Center of Excellence in Vascular Research at Zuckerberg San Francisco General Hospital and Trauma Center. 

Specific patterns of protein levels in our blood could be used to provide a comprehensive “liquid health check” that gives a snapshot of health and potentially an indication of the likelihood that we will develop certain diseases or health risk factors in the future, according to research by scientists in the U.S. and U.K. working with SomaLogic. The results of their proof-of-concept study involving more than 16,000 participants, and published in Nature Medicine, showed that while the accuracy of models based on specific protein expression patterns varied, they were all either better predictors than models based on traditional risk factors, or would constitute more convenient and less expensive alternatives to traditional testing.

Study published in Nature Medicine: https://www.nature.com/articles/s41591-019-0665-2

To read more: https://www.genengnews.com/news/blood-based-liquid-health-check-beats-traditional-predictors-of-multiple-disease-risks/?utm_medium=newsletter&utm_source=GEN+Daily+News+Highlights&utm_content=01&utm_campaign=GEN+Daily+News+Highlights_20191203&oly_enc_id=5678C5137845J4Z

To Improve Healthcare: A New, Unbiased “Health Information Agency” Would Transform System

From a HealthAffairs.org online article:

Health Information AgencyThis proposed agency could work like a seal of approval, like the Energy Star program run by the Environmental Protection Agency, for new software, apps, and vendors that will be handling sensitive health information. Just like dishwashers evaluated by Consumer Reports, apps that handle personal health information should have a similar unbiased review process.   

The US health care system is finally at a tipping point of much needed and overdue modernization. While it promises a brave new world of streamlined and improved health care, we are facing nothing short of a revolutionary transformation that is based on a tsunami of readily accessible health information and digital tools.

Currently, there is no federal agency, public-private collaboration, or private industry mechanism that is prepared to handle the ensuing activity in its entirety. We need to get a handle on how best to protect our private health care data while also making sure that information is allowed to flow as freely as necessary to improve our delivery system and population’s health. We need a dedicated team of experts who speak the language of both information technology and public policy. We need a new federal agency that has jurisdiction and dedicated staff to oversee health information and the technology that will simplify and operationalize the information.

To read more: https://www.healthaffairs.org/do/10.1377/hblog20191108.972878/full/?utm_campaign=HASU&utm_medium=email&utm_content=Association+Health+Plans%3B+HIV+Preventive+Recommendations%3B+Improper+Medicaid+Enrollment+Following+Expansion%3B+Health+Reform+On+The+Campaign+Trail%3B+Frequent+Emergency+Department+Users&utm_source=Newsletter

Health Issues: Middle-Aged Man With Rapid Heart Beat Diagnosed With Sarcoidosis

From a New York Times article by Lisa Sanders, M.D.:

Diagnosis from New York Times by Lisa Sanders, MD Photo Illustration by Ina JangIn sarcoidosis, abnormal collections of cells called granulomas invade the organ, interfering with its normal activity and often destroying the surrounding tissue. What is left is a scar, known as fibrosis, dotted with these abnormal granulomas.

When caught early, sarcoidosis can be treated and the destruction slowed or even stopped. But it was too late for that in this man’s case. He was started on immune-suppressing medications to prevent additional damage, but he needed a new heart.

The man had been active and healthy, until five years earlier when he started to feel tired. His doctor sent him to a cardiologist, who took one look at his EKG and said he needed a pacemaker, right away. He got one the next day. He was fine for a year, and then, on a business trip to Atlanta, he suddenly felt lightheaded, and his heart fluttered wildly in his chest. In the E.R. they told him his heart was beating 220 beats a minute. You should be dead, one doctor said.

To read more click on the following link: https://www.nytimes.com/2019/08/22/magazine/why-was-the-middle-aged-mans-heart-beating-so-dangerously-fast.html

New Health Study: Partial Knee Replacements Should Be “Treatment Of Choice” For Older Patients (The Lancet)

From “The Lancet” published July 17, 2019:

Partial Knee Replacements“Knee replacement is increasing in frequency, and it has an associated substantial cost implication to any health-care provider. It is also essential that patients receive the most efficacious operation for this condition. Before our study, and despite several cohort-based reports, knowledge of whether one operation type is superior, remained uncertain. Our 5-year study has indicated that both TKR and PKR are beneficial interventions but, based on our combined clinical and cost-effectiveness data and providing the operation is performed by those with adequate experience, we recommend that PKR should be offered as the treatment of choice for late-stage isolated medial compartment osteoarthritis of the knee.

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To read entire study click on link below:

https://www.thelancet.com/action/showPdf?pii=S0140-6736%2819%2931281-4

Boomers Health Video: “Ankle Replacement and Ankle Fusion – Surgery and Recovery” (UCTV)

UCTV Health and MedicineOrthopedic surgeon Dr. Daniel Thuillier looks at the options to treat severe ankle pain from nonsteroidal anti-inflammatory drugs to surgery including ankle replacement and ankle fusion.

Series: “Mini Medical School for the Public”