Tag Archives: Brain

Reading Lists: “The Best Neuroscience Books Of 2019” (TheScientist)

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Bury your nose in tales of neurosyphilis, gender identity, the medical mysteries of sleep disorders, and more. JAMES DOLBOW

The Nocturnal Brain by Guy Leschziner

The Nocturnal Brain: Nightmares, Neuroscience and the Secret World of Sleep 

Inspired by the legendary book The Man Who Mistook His Wife for a Hat by the late Oliver Sacks, neurologist and sleep scientist Guy Leschziner tells the curious true stories of his patients, their fascinating sleep disorders, and the neuroscience behind each. Also like the works of Sacks, The Nocturnal Brain is written with considerable introspection and wonder about each patient’s case, taking you on a journey from the first patient encounter, to diagnosis, and through treatment. The unusual and often bizarre cases will keep you intrigued and immersed, and make this unique book one you will find yourself looking forward to making time to read.

How The Brain Lost Its Mind Allan H. Ropper MD and Brian David BurrellHow The Brain Lost Its Mind: Sex, Hysteria, and the Riddle of Mental Health

In this mindful reflection on American and European pasts, authors Allan H. Ropper and Brian Burrell, also the writers of Reaching Down the Rabbit Hole, address our modern concept of mental illness by reviewing the interesting true story of the syphilis epidemic of the 19th century. This little known and fascinating history of neurosyphilis—how it was handled by society and medicine and how it shaped today’s understanding of mental illness—helps address not only why many stigmas exist, but why so many have persisted. This book will take you on an incredible journey through the puzzling diagnosis, eclectic treatments, and lasting social effects of the neurosyphilis epidemic of the 1800s, as well as offer important insight into the difference between diseases of the brain and the mind. This book is perfect for any scientist, psychologist, or historian with even the smallest interest in medical history or mental health theory.

Compassionomics The Revolutionary Scientific Evidence That Caring Makes A Difference Stephen Trzeciak and Anthony MazzarelliCompassionomics: The Revolutionary Scientific Evidence that Caring Makes a Difference

It is no secret that today’s medical atmosphere scarsely resembles anything similar to that of 50 years ago. Many have argued that this is in large part due to a lack of compassion in the modern medical system. If this is the case, where have we gone wrong, and is there scientific evidence to support that compassion is even beneficial to healthcare, personal relationships, and professional lives? These questions are raised and explored by authors Stephen Trzeciak and Anthony Mazzarelli through the telling of true stories of medical providers and patients that help demonstrate the incredible effect of the human connection. Coupled perfectly with these gripping stories are easily readable summaries of decades of research studying the effects of compassion as well as its implications in our lives. Addressing topics from healthcare cost to provider burnout, from caring for others to caring for ourselves, this evidence-based analysis of the importance of compassion is a must-read for anyone interested in the social science and psychology of the care we give in all settings of our lives.

To read more: https://www.the-scientist.com/news-opinion/opinion–the-best-neuroscience-books-of-2019-66863

Studies: “Why Your Brain Needs Exercise” (Scientific American)

From a Scientic American online article:

Scientific American logoIn our own study of more than 7,000 middle-aged to older adults in the U.K., published in 2019 in Brain Imaging and Behavior, we demonstrated that people who spent more time engaged in moderate to vigorous physical activity had larger hippocampal volumes. Although it is not yet possible to say whether these effects in humans are related to neurogenesis or other forms of brain plasticity, such as increasing connections among existing neurons, together the results clearly indicate that exercise can benefit the brain’s hippocampus and its cognitive functions.

New Neurons in Aging Brains Why Your Brain Needs Exercise Scientific American December 18 2019

In fact, a growing body of research suggests that exercise that is cognitively stimulating may indeed benefit the brain more than exercise that does not make such cognitive demands. For example, Gerd Kempermann and his colleagues at the Center for Regenerative Therapies Dresden in Germany explored this possibility by comparing the growth and survival of new neurons in the mouse hippocampus after exercise alone or after exercise combined with access to a cognitively enriched environment. They found an additive effect: exercise alone was good for the hippocampus, but combining physical activity with cognitive demands in a stimulating environment was even better, leading to even more new neurons. Using the brain during and after exercise seemed to trigger enhanced neuron survival.

To read more: https://www.scientificamerican.com/article/why-your-brain-needs-exercise/

Health: “Understanding Parkinson’s Disease” (Nature Videos)

Parkinson’s disease is a neurological condition that affects the brain and other parts of the nervous system. The gradual loss of nerve cells leads to a suite of characteristic motor and non-motor symptoms.

Understanding Parkinson's Disease Nature Neuroscience Videos Dec 16 2019

What causes these cells to die and how the pathology develops in the nervous system are not yet clear but multiple lines of investigation are being pursued to answer these questions. In this animation, we explore some of the latest in Parkinson’s disease research.

Website: https://www.nature.com/articles/s41583-019-0254-x

Health Studies: Poor Sleep Associated With Non-Alzheimer’s Dementia And Impaired Cognition

From a University of Toronto Medicine article:

University of Toronto Medicine“There are two important takeaways from this paper. One is that poor sleep is associated with brain immune dysregulation or dysfunction,” says Lim, the corresponding author for the paper.

“The second part is that dysfunction appears to be further associated with impaired cognition.”

The study shows that in adults with fragmented sleep – where people were waking up repeatedly instead of sleeping soundly – there was an effect on microglia, and the cells showed signs of accelerated aging and other abnormalities.

The researchers were then able to identify that these changes in the microglia could be associated with worse cognition in older adults, both with and without Alzheimer’s disease.

To read full study: https://advances.sciencemag.org/content/5/12/eaax7331

To read more: https://medicine.utoronto.ca/news/research-suggests-fragmented-sleep-may-affect-brain-s-immune-cells-impair-cognition

Insites Into Neuroscience: “EEG – A Mental Map” Infographic (IMotions)

Knowing how someone thinks is crucial to understanding their behavior. With EEG (electroencephalography), you can get access to this hidden world, and reveal what’s really going on in someone’s mind. EEG offers many advantages, but it can be tricky to get your head around in the beginning. This infographic from iMotions is designed to give you a head start to this powerful technology.

EEG-infographics-2018

Health Studies: Reduced Mental Alertness (“Brain Fog”) Is Caused By Inflammation In The Body

From a Genetic Engineering & Biotechnology News release:

NeuroImage Journal“These results show quite clearly that there’s a very specific part of the brain network that’s affected by inflammation,” noted Mazaheri. “This could explain ‘brain fog’.”

Raymond added that “this research finding is a major step forward in understanding the links between physical, cognitive, and mental health and tells us that even the mildest of illnesses may reduce alertness.”

Researchers at the University of Birmingham’s Centre for Human Brain Health in collaboration with the University of Amsterdam say they have uncovered a possible explanation for the mental sluggishness that often accompanies illness. The team investigated the link between “mental fog” and inflammation, the body’s response to illness. In a study (“Selective effects of acute low-grade inflammation on human visual attention”) published in Neuroimage, they showed that inflammation appears to have a particularly negative impact on the brain’s readiness to reach and maintain an alert state.

To read more: https://www.genengnews.com/news/link-found-between-inflammation-and-mental-sluggishness/?utm_medium=newsletter&utm_source=GEN+Daily+News+Highlights&utm_content=01&utm_campaign=GEN+Daily+News+Highlights_20191118&oly_enc_id=5678C5137845J4Z

Brain Research: We Make Decisions Based On Memories To Maximize Reward Received

From a Geneva University Neurocenter release:

Geneva University Neurocenter.JPG…the optimal strategy when faced with two propositions is to sum up the values associated with the memories you have of each choice, then calculate the difference between these two sums (do I have more positive memories linked to chocolate eclairs or macaroons?). The decision is made when this difference reaches a threshold value, fixed in advance, which determines the time taken in making the decision. This model leads to rapid decision-making when the values of the two possibilities are very far apart. But when two choices have almost the same value, we need more time, because we need to draw on more memories so that this difference reaches the decision threshold.

Our brains are constantly faced with different choices: Should I have a chocolate éclair or macaroon? Should I take the bus or go by car? What should I wear: a woollen sweater or one made of cashmere? When the difference in quality between two choices is great, the choice is made very quickly. But when this difference is negligible, we can get stuck for minutes at a time – or even longer – before we’re capable of making a decision. Why is it so difficult to make up our mind when faced with two or more choices? Is it because our brains are not optimised for taking decisions? In an attempt to answer these questions, neuroscientists from the University of Geneva (UNIGE), Switzerland, – in partnership with Harvard Medical School – developed a mathematical model of the optimal choice strategy. They demonstrated that optimal decisions must be based not on the true value of the possible choices but on the difference in value between them. The results, which you can read all about in the journal Nature Neuroscience, show that this decision-making strategy maximises the amount of reward received.

To read more: https://neurocenter-unige.ch/news/brain-how-to-optimize-decision-making/