Non-Alzheimer’s Demential

From a University of Toronto Medicine article:

“There are two important takeaways from this paper. One is that poor sleep is associated with brain immune dysregulation or dysfunction,” says Lim, the corresponding author for the paper.

“The second part is that dysfunction appears to be further associated with impaired cognition.”

The study shows that in adults with fragmented sleep – where people were waking up repeatedly instead of sleeping soundly – there was an effect on microglia, and the cells showed signs of accelerated aging and other abnormalities.

The researchers were then able to identify that these changes in the microglia could be associated with worse cognition in older adults, both with and without Alzheimer’s disease.

To read full study: https://advances.sciencemag.org/content/5/12/eaax7331