

Online News Editor David Grimm joins host Sarah Crespi to discuss a controversial new paper that estimates how many rodents are used in research in the United States each year.
Though there is no official number, the paper suggests there might be more than 100 million rats and mice housed in research facilities in the country—doubling or even tripling some earlier estimates.
Next, Staff Writer Jennifer Couzin-Frankel talks with Sarah about a new theory behind the cause of irritable bowel syndrome—that it might be a localized allergic reaction in the gut. Sarah also chats with Taline Kazandjian, a postdoctoral research associate at the Centre for Snakebite Research & Interventions in Liverpool, U.K., about how the venom from spitting cobras has evolved to cause maximum pain and why these snakes might have developed the same defense mechanism three different times.
How has Einstein’s work on photons ushered in a golden age of light? Oliver Morton, The Economist’s briefings editor, explores why laser’s applications have been spectacular and how solar power became the cheapest source of electricity in many countries.
Also, he talks to the scientists scanning the skies with the largest digital camera in the world.
As new coronavirus variants sweep across the world, scientists are racing to understand how dangerous they could be. WSJ explains. Illustration: Alex Kuzoian/WSJ
Science Senior Correspondent Daniel Clery regales host Sarah Crespi with tales about the most important work to come from 57 years of research at the now-defunct Arecibo Observatory and plans for the future of the site.
Sarah also talks with Toman Barsbai, an associate professor in the school of economics at the University of Bristol, about the influence of ecology on human behavior—can we figure out how many of our behaviors are related to the different environments where we live? Barsbai and colleagues took on this question by comparing behaviors around finding food, reproduction, and social hierarchy in three groups of animals living in the same places: foraging humans, nonhuman mammals, and birds.
Benjamin Thompson, Noah Baker and Elie Dolgin discuss RNA vaccines.
In this episode:
01:16 How RNA vaccines came to prominence
In less than a year, two RNA vaccines against COVID-19 were designed, tested and rolled out across the world. We discuss these vaccines’ pros and cons, how RNA technology lends itself to rapid vaccine development, and what this means for the fight against other diseases.
News feature: How COVID unlocked the power of RNA vaccines
09:20 The hurdles for trialling new COVID-19 vaccines
Multiple candidates for new COVID-19 vaccines are still being developed, which may offer advantages over the vaccines currently available. However, running placebo-controlled trials of these candidates is becoming increasingly difficult, so researchers are looking for different ways to evaluate them.
News: Search for better COVID vaccines confounded by existing rollouts
14:45 How long will COVID vaccines be effective?
There is much concern around the world about two faster-spreading variants of SARS-CoV-2. We get an update on whether these variants could render vaccines ineffective.
News: Could new COVID variants undermine vaccines? Labs scramble to find out
DNA clues point to how dire wolves went extinct, and a round-up of the main impacts of Brexit on science.
In this episode:
00:45 Dire wolf DNA
Dire wolves were huge predators that commonly roamed across North America before disappearing around 13,000 years ago. Despite the existence of a large number of dire wolf fossils, questions remain about why this species went extinct and how they relate to other wolf species. Now, using DNA and protein analysis, researchers are getting a better understanding of what happened to these extinct predators.
Research Article: Perri et al.
11:43 Research Highlights
The secret to Pluto’s blue haze, and the neural circuitry underlying mice empathy.
Research Highlight: Ice bathes Pluto in a blue haze
Research Highlight: Brain maps show how empathetic mice feel each other’s pain
13:31 Post-Brexit science
In December, a last minute trade-deal between the UK and EU clarified what the future relationship between the two regions would look like, after Brexit. We discuss the implications of this trade-deal for science funding, the movement of researchers, and data sharing.
News Explainer: What the landmark Brexit deal means for science
23:18 Briefing Chat
We discuss some highlights from the Nature Briefing. This time, concerns about contaminating water on the moon, and the spy satellites that spied out environmental change.
Nature News: Will increasing traffic to the Moon contaminate its precious ice?
The New York Times: Inside the C.I.A., She Became a Spy for Planet Earth
Messenger RNA—or mRNA—vaccines have been in development for decades, and are now approved for use against COVID-19. Here’s how they work and what you should know about them. Visit https://www.jhsph.edu/covid-19 for even more resources.