Technologies in development for delivering vaccines include Enesi’s dissolving implants, microneedle patches, electrical-pulse systems, nasal sprays and even pills.
Some firms are developing their own vaccines against Covid-19, while others are aiming to reformulate some of the dozens already in development or being rolled out world-wide. Some are sitting this pandemic out in the hope of being ready for the next one.
All are in the early to mid-stages of development and clinical testing, suggesting it might be months if not years before they come to market. Big pharmaceutical companies have so far shown limited interest.
The pandemic’s unequal toll on the research community, and a newly discovered mitochondria-like symbiosis.
In this episode:
00:48 The pandemic’s unequal toll on researchers
Although 2020 saw a huge uptick in the numbers of research papers submitted, these increases were not evenly distributed among male and female scientists. We look at how this could widen existing disparities in science, and damage future career prospects.
Millions of years ago, a microscopic protist swallowed a bacterium and gained the ability to breathe nitrate. This relationship partially replaced the cell’s mitochondria and allowed it to produce abundant energy without oxygen. This week, researchers describe how this newly discovered symbiosis works.
We discuss some highlights from the Nature Briefing. This time, the weakening of the Gulf Stream, and a new satellite to monitor deforestation in the Amazon.
Is the future of deep-sea exploration soft? Researchers have developed a new type of soft robot designed to cope with the crushing pressures at the bottom the ocean. Inspired by the skull of the Mariana Snailfish, the deepest living fish, the researchers distributed their robot’s electronics, creating a machine that can withstand extreme pressure.
Enter the intranasal vaccine, which abandons the needle and syringe for a spray container that looks more like a nasal decongestant. With a quick spritz up the nose, intranasal vaccines are designed to bolster immune defenses in the mucosa, triggering production of an antibody known as immunoglobulin A, which can block infection. This overwhelming response, called sterilizing immunity, reduces the chance that people will pass on the virus.
The development of highly effective COVID vaccines in less than a year is an extraordinary triumph of science. But several coronavirus variants have emerged that could at least partly evade the immune response induced by the vaccines. These variants should serve as a warning against complacency—and encourage us to explore a different type of vaccination, delivered as a spray in the nose. Intranasal vaccines could provide an additional degree of protection, and help reduce the spread of the virus.
How can you tell if the mask you’re wearing is protective enough against the coronavirus? Correspondent David Pogue volunteers as a test subject to see how N95s work and learns about the science of face coverings.
First up, science journalist Julia Rosen talks with host Sarah Crespi about a growing fleet of radar satellites that will soon be able to detect minute rises and drops of Earth’s surface—from a gently deflating volcano to a water-swollen field—on a daily basis.
Sarah also talks with Hui Cao, a professor of applied physics at Yale University, about a new way to generate enormous streams of random numbers faster than ever before, using a tiny laser that can fit on a computer chip.
Theoretical Physicist, String Theorist and Professor, Brian Greene looks at how time travel is portrayed in popular films. You can get his new book, Until the End of Time, here: https://amzn.to/3pTGyVx
Until the End of Time is Brian Greene’s breathtaking new exploration of the cosmos and our quest to understand it. Greene takes us on a journey across time, from our most refined understanding of the universe’s beginning, to the closest science can take us to the very end. He explores how life and mind emerged from the initial chaos, and how our minds, in coming to understand their own impermanence, seek in different ways to give meaning to experience: in story, myth, religion, creative expression, science, the quest for truth, and our longing for the timeless, or eternal.
Through a series of nested stories that explain distinct but interwoven layers of reality-from the quantum mechanics to consciousness to black holes-Greene provides us with a clearer sense of how we came to be, a finer picture of where we are now, and a firmer understanding of where we are headed. Yet all this understanding, which arose with the emergence of life, will dissolve with its conclusion. Which leaves us with one realisation: during our brief moment in the sun, we are tasked with the charge of finding our own meaning. Let us embark.
News, Views and Reviews For The Intellectually Curious
Boomers Daily 