Diet Studies: 2-Year Calorie Restriction Diets Lower LDL/Total Cholesterol, C-Reactive Protein & Blood Pressure

From The Lancet Diabetes & Endocrinology:

Calorie Restriction The Lancet Diabetes & Endocrinology Sept 20192 years of moderate calorie restriction significantly reduced multiple cardiometabolic risk factors in young, non-obese adults. These findings suggest the potential for a substantial advantage for cardiovascular health of practicing moderate calorie restriction in young and middle-aged healthy individuals, and they offer promise for pronounced long-term population health benefits.

Calorie restriction caused a persistent and significant reduction from baseline to 2 years of all measured conventional cardiometabolic risk factors, including change scores for LDL-cholesterol (p<0·0001), total cholesterol to HDL-cholesterol ratio (p<0·0001), and systolic (p<0·0011) and diastolic (p<0·0001) blood pressure. In addition, calorie restriction resulted in a significant improvement at 2 years in C-reactive protein (p=0·012), insulin sensitivity index (p<0·0001), and metabolic syndrome score (p<0·0001) relative to control. A sensitivity analysis revealed the responses to be robust after controlling for relative weight loss changes.

To read more click on following link: https://www.thelancet.com/journals/landia/article/PIIS2213-8587(19)30151-2/fulltext?dgcid=raven_jbs_etoc_email

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