The successful use of engineered white blood cells (cells that are removed from the human body, modified with receptors that allow them to recognize cancer cells, and then returned to the body) to fight and eliminate tumor cells has frequently been called revolutionary and has even allowed researchers the rare opportunity to refer to a cure for certain cancers.
California is having more and more wildfires because of climate change, poor tree management creating fire hazards, and antiquated power lines. In 2018, the failure of a 100-year-old rusted electrical hook sparked the Camp Fire, the world’s most expensive natural disaster that year. The blaze forced Pacific Gas and Electric into temporary bankruptcy. Journalist Katherine Blunt’s disturbing history of California’s environmental calamity ends in 2021, with the company’s new chief executive announcing costly underground power lines.
The Biggest Ideas in the Universe
Sean Carroll Oneworld (2022)
Theoretical physicist and philosopher Sean Carroll specializes in quantum mechanics, gravity and cosmology. He aims to create a world in which “most people have informed views and passionate opinions” about modern physics. His skilful book, the first of a planned trilogy, covers space, time and motion. Unlike most introductory physics books for the interested amateur, it includes mathematical equations, cogently explained but not solved, as well as the expected metaphorical language.
Cancer Virus Hunters
Gregory J. Morgan Johns Hopkins Univ. Press (2022)
One-fifth of cancers in people worldwide are caused by tumour viruses such as hepatitis B. Work stemming from these pathogens won seven Nobel prizes between 1966 and 2020, notes historian Gregory Morgan in his authoritative but accessible chronicle. Yet tumour virology is rarely mentioned in discussions of how molecular biology opened our understanding of cancer. As Morgan observes in his path-breaking history, this inhibits a complete understanding of this field as a technoscientific force.
Planta Sapiens
Paco Calvo with Natalie Lawrence Bridge Street (2022)
Humans are so focused on “brain-centric consciousness”, says philosopher of science Paco Calvo, “that we find it difficult to imagine other kinds of internal experience”. Might plants be intelligent (‘sapiens’)? His challenging book is aimed at both believers in this possibility and non-believers. His experiments, such as putting the touch-sensitive plant Mimosa pudica to ‘sleep’ with anaesthetic, provoke thought, as does his note that Charles Darwin requested burial under an ancient village yew, rather than in Westminster Abbey.
Ritual
Dimitris Xygalatas Profile (2022)
Just before anthropologist Dimitris Xygalatas’s university went into COVID-19 lockdown, his students had one main concern: would there be a graduation ceremony? We care deeply about rituals, he notes in his wide-ranging and well-written survey, because they help us to “cope with many of life’s challenges”, even if we do not understand how — the “ritual paradox”. Scientific investigation has been tricky, because rituals do not flourish in a laboratory, but wearable sensors and brain-imaging technology help.
With a growing number of people living with pain, we desperately need to understand it – but we are still unravelling the mysterious mechanisms behind the phenomenon
FEATURES – Roger Penrose: “Consciousness must be beyond computable physics”
FEATURES – Why emotions can feel so painful – and what it means for painkillers
FEATURES – We are only just beginning to understand what causes nociplastic pain
On this week’s show: How sci-fi writer Kurt Vonnegut foresaw many of today’s ethical dilemmas, and 70 years of tunas, billfishes, and sharks as sentinels of global ocean health
First up this week on the podcast, we revisit the works of science fiction author Kurt Vonneugt on what would have been his 100th birthday. News Intern Zack Savitsky and host Sarah Crespi discuss the work of ethicists, philosophers, and Vonnegut scholars on his influence on the ethics and practice of science. Researchers featured in this segment:
Peter-Paul Verbeek, a philosopher of science and technology at the University of Amsterdam and chair of the World Commission on the Ethics of Scientific Knowledge and Technology David Koepsell, a philosopher of science and technology at Texas A&M University, College Station Christina Jarvis, a Vonnegut scholar at the State University of New York, Fredonia, and author of the new book Lucky Mud & Other Foma: A Field Guide to Kurt Vonnegut’s Environmentalism and Planetary Citizenship Sheila Jasanoff, a science studies scholar at Harvard University
Next, producer Kevin McLean discusses the connection between fishing pressure and extinction risk for large predatory fish such as tunas and sharks. He’s joined by Maria José Juan Jordá, a postdoc at the Spanish Institute for Oceanography, to learn what a new continuous Red List Index using the past 70 years of fisheries data can tell us about the effectiveness and limits of fishing regulations. Finally, in a sponsored segment from the Science/AAAS Custom Publishing Office, Sean Sanders, director and senior editor for custom publishing, interviews Joseph Hyser, assistant professor in the Department of Molecular Virology and Microbiology at Baylor College of Medicine about his use of wide-field fluorescence live cell microscopy to track intercellular calcium waves created following rotavirus infection.