Hazen and colleagues find that gut bacteria play a central role in the conversion of dietary proteins into a compound, phenylacetylglutamine ( PAGln), which not only is associated with future cardiovascular disease risk in humans but also promotes platelet responsiveness and blood clotting potentially via adrenergic receptors, according to mouse models.
Category Archives: Medicine
Study: Sunlight Exposure Lowers Blood Pressure, Avoiding It Is Risk Factor For Hypertension (AHA)
From an American Heart Assoc. Journal study (Feb 28, 2020):
Seasonal variation in blood pressure has been known for 40 years, but, to our knowledge, for the first time we show here that this occurs independently of temperature. The reduction in blood pressure is more marked with a rise in UVB than UVA, and in whites than black people. Dermatological concerns about the skin cancer inducing effects of UV radiation need to be balanced against the observed blood pressure lowering effects of sunlight, particularly given the greatly higher burden of disease caused by hypertension.
Sunlight exposure appears to lower blood pressure; insufficient exposure to natural ultraviolet radiation and/or active avoidance of sunlight may be new risk factors for hypertension.
Hypertension remains a leading global cause for premature death and disease. Most treatment guidelines emphasize the importance of risk factors, but not all are known, modifiable, or easily avoided. Population blood pressure correlates with latitude and is lower in summer than winter. Seasonal variations in sunlight exposure account for these differences, with temperature believed to be the main contributor. Recent research indicates that UV light enhances nitric oxide availability by mobilizing storage forms in the skin, suggesting incident solar UV radiation may lower blood pressure. We tested this hypothesis by exploring the association between environmental UV exposure and systolic blood pressure (SBP) in a large cohort of chronic hemodialysis patients in whom SBP is determined regularly.
Coronavirus / Covid -19: “What Happens When It Enters Your Body” (Video)
What happens when you catch coronavirus? The Telegraph’s Global Health Security Editor Paul Nuki explains all the ways in which you could become infected with COVID-19 and how your body reacts to this virus.
What happens when the virus enters the body?
When the virus enters your body it binds to two cells in the lungs – goblet cells that produce mucus and cilia cells which have hairs on them and normally prevent your lungs filling up with debris and fluid such as virus and bacteria and particles of dust and pollen.
The virus attacks these cells and starts to kill them – so your lungs begin to fill with fluid making it hard for you to breathe. This phase of the disease is thought to last about a week.
At this point your immune system will start to kick in and fight off the invaders. You will develop a fever and your high body temperature will create a hostile environment for the virus. You will start to get rid of the mucus in the form of coughing and a runny nose.
But in some people – particularly the elderly and those with other health conditions – the immune system can go into overdrive. As well as killing the virus it also starts to kill healthy cells.
This heightened immune response can trigger a “cytokine storm” – white blood cells activate a variety of chemicals that can leak into the lungs, which along with the attack on the cells damages them even further. Scans of the lungs show “ground-glass” opacity and then “crazy paving” patterns, as they fill with mucus making it harder and harder to breathe.
Health: All Adults 18-79 Should Be Screened For Hepatitis C Virus (HCV)
From a Stanford University online article (March 2, 2020):
“The opioid epidemic has added fuel to the HCV fire, substantially increasing transmission,” said Owens. “HCV is now an enormous public health problem, affecting a much broader age range of people than before. Fortunately, we have the tools to identify people and treatment is now successful in the vast majority of patients, so screening can prevent the mortality and morbidity from HCV.”
A task force of national health experts recommends clinicians screen all adults 18 to 79 for the hepatitis C virus (HCV), noting that the viral infection is now associated with more deaths in the United States than the top 60 reportable infectious diseases combined. Many people are unaware they are carrying the viral infection.
“People with hepatitis C do not always feel sick and may not know they have it,” says chair of the U.S. Preventive Services Task Force Douglas K. Owens, M.D, M.S. “Screening is key to finding this infection early, when it’s easier to treat and cure, helping reduce illnesses and deaths.”
Owens, who is the director of Stanford Health Policy and the Henry J. Kaiser, Jr., Professor of Medicine, said the opioid epidemic now plays an important role in the prevalence of HCV. There are more than three times the number of acute HCV cases than a decade ago, particularly among young, white, injection drug users who live in rural areas. Women aged 15 to 44 have also been hit hard by the virus that is spread through contaminated blood.
Medicine: “Relentless Prescription Drug Price Increases” (JAMA Podcast)
Drug Pricing Theme Issue: Is Pharma Earning Too Much?, R&D Costs Required to Bring a New Drug to Market, Probiotic Safety, and more
One in 4 people in the US has difficulty paying the cost of their prescription medications. This stark fact was recently reported in a 2019 Kaiser Family Foundation public opinion poll among a nationally representative random sample of 1205 adults.1 Persons who reported having the greatest difficulty affording their prescription drugs were those who most needed them, including those who took 4 or more prescription drugs, spent $100 or more per month on their drugs, and reported being in fair or poor health.
Infographics: “Cancer And The Immune System”
W.H.O. Update: 80% Of “Coronavirus/Covid-19” Patients – “Mild Symptoms”
Mar.03 — World Health Organization spokesman Tarik Jasarevic speaks from Geneva about the latest advice for avoiding the coronavirus. He also comments on efforts to develop a vaccine and advice for public health workers. He speaks on “Bloomberg Markets: European Open.”
Health Talk: “Macular Degeneration” – Diagnosis & Treatment (Mayo Clinic)
On the Mayo Clinic Radio podcast, Dr. Sophie Bakri, a Mayo Clinic ophthalmologist and retina specialist, discusses macular degeneration, a common eye disorder with age. This interview originally aired Feb. 29, 2020.
Dry macular degeneration is a common eye disorder among people over 50. It causes blurred or reduced central vision, due to thinning of the macula (MAK-u-luh). The macula is the part of the retina responsible for clear vision in your direct line of sight.
Dry macular degeneration may first develop in one eye and then affect both. Over time your vision may worsen and affect your ability to do things such as read, drive and recognize faces. But this doesn’t mean you’ll lose all of your sight.
Early detection and self-care measures may delay vision loss due to dry macular degeneration.
Health: Why U.S. Life Expectancy Stopped Declining In 2018
A slight uptick in U.S. life expectancy in the U.S. in 2018 was due partly to a decrease in overdose deaths, but mostly to decreasing cancer deaths.
Health: What To Expect From The Spread Of Coronavirus (Covid-19)
In public health, honesty is worth a lot more than hope. It has become clear in the past week that the new viral disease, covid-19, which struck China at the start of December will spread around the world. Many governments have been signalling that they will stop the disease. Instead, they need to start preparing people for the onslaught
Boomers Daily 