
New Scientist Magazine – 4 June 2022
COVER STORIES
With six sets of chromosomes, the hexaploid cultivated oat (Avena sativa L.) has a complex evolutionary history. In this week’s issue, Nick Sirijovski and his colleagues present a high-quality reference genome for A. sativa alongside those for its close relatives the diploid Avena longiglumis and the tetraploid Avena insularis. By examining the three genomes, the researchers were able to trace genomic reorganizations in the crop’s evolution. They were also able to map the genes for important agronomic traits, highlighting gene families linked to human health and nutrition. With health and sustainability high on global agendas, the team hopes this new resource will bolster genomics-assisted breeding and trait studies to address these challenges and more.
Can the aging process be reversed – or even halted, altogether? If we manage to decode this final mystery of our human biology, we might soon be able to eradicate age-related illnesses like cancer, dementia and heart problems. The race to invent the miracle pill is well underway.
Today, international researchers are getting astonishingly close to realizing humanity’s dream of immortality. The hunt for immortality gained traction with the discovery of Costa Rica’s so-called “Blue Zone,” by Luis Rosero-Bixby. In the “Blue Zone,” on the Nicoya Peninsular, he found a remarkable number of centenarians.
Here, male life expectancy is the highest in the world. Their healthy lifestyle is one factor, but the promise of longevity is probably also because their telomeres – sections of DNA found at the end of chromosomes – are longer than those of the average person. It’s a field of research currently being explored by Maria Blasco in Madrid.
But this is just one of many possible factors influencing the process of aging. Senescent cells may also play a key role. Also known as “zombie cells”, these attack our body in old age and flood it with alarm signals until, at some point, we collapse under their weight. That’s a theory proposed by another researcher in Spain, Manuel Serrano. A billion-dollar industry is already knocking impatiently at the lab doors.
The first to market the miracle pill is guaranteed incredible wealth. That’s why investors are sponsoring young bio-startups in Hong Kong. Keen not be left out, US Big Tech is vying for the world’s best scientists. Alex Zhavoronkov has secured a slice of that pie, with a cash injection of more than 250 million dollars for his company’s work on aging research. Whereas some pioneers’ visions burst like bubbles, others rush to get other, rather more dubious products onto the market. But their efficacy is now measurable.
The epigenetic clock devised by Steve Horvath can measure our biological age, regardless of our actual age in years. With his research on the thymus gland, California’s Greg Fahy managed to not only decelerate the aging process, but reverse it. His initial study on humans showed that a particular drug cocktail took an average two-and-a-half years off their age.
Young biohackers like Nina Khera from Boston want everyone to benefit from this research. Together with friends, she’s working on the “epigenetic clock for all”. But while we’re busy trying to counter the aging process and all the illnesses it entails, fundamental questions arise: Should we be messing with nature like this? Are we about to overwhelm the planet with more and more people? Criminal biologist Mark Benecke in Cologne says that these questions are coming far too late.
Cilia are characterized by slender, threadlike projections, which are used by biological organisms to control fluid flows at the microscale. Attempts to mimic these structures and engineer cilia-like systems to have broad applications have proved problematic. In this week’s issue, Wei Wang and colleagues present electronically controlled artificial cilia that can be used to create flow patterns in near-surface liquids. The researchers use surface-mounted platinum strips, each about 50 micrometres long, 5 micrometres wide and 10 nanometres thick, and capped on one side with titanium. Applying an oscillating potential with an amplitude of around 1 volt to the cilia drives ions on to and off of the exposed platinum surface. These ions create asymmetric forces that generate a beating pattern that can be used to pump surface liquids in various flow geometries. The cover shows an artist’s impression of the artificial cilia in action.
The puzzle of Palaeospondylus – Over a hundred years ago, archaeologists discovered fossils of the aquatic animal Palaeospondylus. But since then researchers have been unable to place where this animal sits on the tree of life. Now, new analysis of Palaeospondylus’s anatomy might help to solve this mystery.
A strong, silk-based version of mother of pearl, and the parrots that use their heads when climbing.
Research Highlight: Silk imitates mother of pearl for a tough, eco-friendly material
Research Highlight: A ‘forbidden’ body type? These parrots flout the rules
Archaeologists have used LiDAR to uncover evidence of an ancient civilization buried in the Bolivian Amazon. The team’s work suggests that this area was not as sparsely populated in pre-Hispanic times as previously thought.
Research article: Prümers et al.
News and Views: Large-scale early urban settlements in Amazonia
Nature Video: Lost beneath the leaves: Lasers reveal an ancient Amazonian civilisation
We discuss some highlights from the Nature Briefing. This time, the debate surrounding the first transplant of pig kidneys into humans, and the plants grown in lunar soil.
Nature News: First pig kidneys transplanted into people: what scientists think
COVER STORIES
Dark matter makes up most of the matter in the Universe, and is thought to be needed for galaxies to form. But four years ago, astronomers made a perplexing, and controversial discovery: two galaxies seemingly devoid of dark matter.
This week the team suggests that a cosmic collision may explain how these, and a string of other dark-matter-free galaxies, could have formed.
Research article: van Dokkum et al
News and Views: Giant collision created galaxies devoid of dark matter
How fossil fuel burning has caused levels of helium to rise, and a high-efficiency, hybrid solar-energy system.
Research Highlight: Helium levels in the atmosphere are ballooning
Research Highlight: Flower power: ‘Sunflower’ system churns out useful energy
We hear the stories of scientists whose lives have been affected by Russia’s invasion of Ukraine, including researchers who have become refugees, soldiers and activists in the face of a horrifying conflict.
Nature Feature: How three Ukrainian scientists are surviving Russia’s brutal war
Last week, a team of researchers released an image of Sagittarius A*, the supermassive blackhole at the centre of our galaxy. We hear how they took the image and what it is revealing about these enormous objects.
Nature News: Black hole at the centre of our Galaxy imaged for the first time