From a MD Magazine online release:
The investigators discovered that patients with a higher genetic risk for depression were more likely to be diagnosed with depression over the next 2 years. However, more physically active patients at baseline were less likely to depression, even after they accounted for genetic risks.
Increasing physical activity could pay dividends for people with a high risk of developing depression.
A team from Massachusetts General Hospital (MGH) recently discovered that several hours of weekly exercise result in a decreased chance to be diagnosed with a new episode of depression, even in patients with a higher genetic risk of developing Major Depressive Disorder (MDD).
The team examined the genomic and electronic health record (EHR) data of approximately 8000 patients in the Partners Healthcare Biobank, which represents the first study to show how physical activity influences depression despite genetic risk.