Colin Cowherd talks with Dr. Patrick Soon-Shiong who is not only a Doctor helping to fight Covid-19 but also owns the LA Times and is a minority owner of the Lakers. Dr. Shiong talks about the things we are learning about the disease and why it is so much more dangerous than previous pandemics.
Dr Patrick Soon-Shiong is a South African-American billionaire surgeon, businessman, media mogul, and bioscientist. He is the inventor of the drug Abraxane, which became known for its efficacy against lung, breast, and pancreatic cancer.
Benjamin Thompson, Noah Baker, and Amy Maxmen discuss Trump withholding funds from the WHO, and how COVID-19 kills. We also hear about controlling misinformation while communicating risk.
In this episode:
01:15 Understanding bottlenecks
After listening to last week’s episode of Coronapod, researchers in the USA were inspired to start collecting data about the challenges facing labs carrying out testing. After more than 4,000 responses to their online survey, we discuss their goals.
03:08 A hole in the WHO’s funding
US President Donald Trump has announced plans to withhold funding for the WHO, pending a review of the organization’s handling of the pandemic. We discuss the decision and ask what it means for the global response to COVID-19.
We investigate the role of the immune system in the death of COVID-19 patients and what this could mean for treatments. Could some therapeutics actually be undermining the body’s ability to fight the virus?
Our hosts pick out things that have made them smile in the last 7 days, including seasonal memories from Sierra Leone, a trip to the supermarket, and the 99-year old war veteran who has raised millions for charity.
Clearly communicating risks and evidence is key for governments and other organisations if they are to best inform the public during the pandemic. But what is the best way to do it? We hear the methods that communications experts and behavioural scientists recommend to keep the public informed, and keep misinformation at bay.
On this week’s show, Contributing Correspondent Kai Kupferschmidt talks with host Sarah Crespi about modeling coronavirus spread and the role of forecasts in national lockdowns and other pandemic policies. They also talk about the launch of a global trial of promising treatments.
Also this week, Nadine Gogolla, research group leader at the Max Planck Institute of Neurobiology, talks with Sarah about linking the facial expressions of mice to their emotional states using machine learning.
Listen to the latest from the world of science, brought to you by Benjamin Thompson and Nick Howe. This week, Nautre speaks to Rosamund Pike about her experience portraying Marie Skłodowska Curie, and we find out how science in Russia is changing after years of decline.
In this Podcast Extra, we hear from epidemiologists, genomicists and social scientists about how they’re working to tackle the coronavirus and what they’ve learned so far.
On this week’s show, freelance writer Christa Lesté-Lasserre talks with host Sarah Crespi about the scientists working on the restoration of Notre Dame, from testing the changing weight of wet limestone, to how to remove lead contamination from four-story stained glass windows.
As the emergency phase of work winds down, scientists are also starting to use the lull in tourist activity to investigate the mysteries of the cathedral’s construction.
Also this week, Felipe Quiroz, an assistant professor in the biomedical engineering department at the Georgia Institute of Technology and Emory University, talks with Sarah about his paper on the cellular mechanism of liquid-liquid phase separation in the formation of the tough outer layer of the skin. Liquid-liquid phase separation is when two liquids “demix,” or separate, like oil and water. In cells, this process created membraneless organelles that are just now starting to be understood. In this work, Quiroz and colleagues create a sensor for phase separation in the cell that works in living tissue, and show how phase separation is tied to the formation of the outer layers of skin in mice.
The hope, Lee says, is that ultrasound will kill cancer cells in a specific way that will also engage the immune system and arouse it to attack any cancer cells remaining after the treatment.
A new technique could offer a targeted approach to fighting cancer: low-intensity pulses of ultrasound have been shown to selectively kill cancer cells while leaving normal cells unharmed.
Ultrasound waves—sound waves with frequencies higher than humans can hear—have been used as a cancer treatment before, albeit in a broad-brush approach: high-intensity bursts of ultrasound can heat up tissue, killing cancer and normal cells in a target area. Now, scientists and engineers are exploring the use of low-intensity pulsed ultrasound (LIPUS) in an effort to create a more selective treatment.
A study describing the effectiveness of the new approach in cell models was published in Applied Physics Letters on January 7. The researchers behind the work caution that it is still preliminary—it still has not been tested in a live animal let alone in a human, and there remain several key challenges to address—but the results so far are promising.
Structural biologists rejoiced when cryo–electron microscopy, a technique to generate highly detailed models of biomolecules, emerged. But years after its release, researchers still face long queues to access these machines. Science’s European News Editor Eric Hand walks host Meagan Cantwell through the journey of a group of researchers to create a cheaper, more accessible alternative.
Also this week, host Joel Goldberg speaks with psychiatrist and researcher Goodman Sibeko, who worked with the Xhosa people of South Africa to help illuminate genetic details of schizophrenia. Though scientists have examined this subject among Western populations, much less is known about the underlying genetics of people native to Africa.
During this decade, as in previous decades, Caltech scientists and engineers reinvented the landscape of scientific endeavor: from the first detection of gravitational waves and the discovery of evidence for a ninth planet in the solar system; to bold missions to explore and understand the solar system; to the development of new methods to see inside the body and the brain and understand the universe around us; to the invention of devices to improve human health, some taking inspiration from nature; to the initiation of a transformative new effort to support research into the most pressing challenges in environmental sustainability.
Though the brain orchestrates how we experience the world, many questions remain about its complex workings. During the past 10 years, Caltech scientists have discovered how the brain recognizes faces and drives and quenches thirst, and learned about the pathways that govern sleep. A major focus has been on understanding the experience of non-neurotypical individuals, such as those who have autism or those who are missing a brain hemisphere. New realms of neuroscience research were made possible in 2016, when philanthropists Tianqiao and Chrissy Chen announced a gift to establish the Tianqiao and Chrissy Chen Institute for Neuroscience at Caltech.