Category Archives: Medicine

Heart Health: Cardiology Magazine – March 2023

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CARDIOLOGY MAGAZINE – MARCH 2023 ISSUE:

The Triple Whammy: Obesity, Diabetes and Sleep-Disordered Breathing and Their Impact on CVD

MARCH 2023

“It’s extremely important we as health care professionals address diabetes, poor sleep and poor sleep hygiene, and obesity as they are modifiable risk factors for cardiovascular disease,” says Nishant P. Shah, MD, FACC, a preventive cardiologist at Duke Heart Center, Duke University School of Medicine, in Durham, NC.

Obesity, diabetes and sleep-disordered breathing (SDB) are considered to be extant and growing public health crises. A wealth of information links these conditions to each other and to increased morbidity, reduced quality of life and death. While managing these conditions that often occur together may be challenging for patients and clinicians, successfully addressing them represents a real opportunity to reduce cardiovascular disease and prevent cardiovascular events.

READ CARDIOLOGY MAGAZINE DIGITAL ISSUE ONLINE

Research: New Scientist Magazine- February 4, 2023

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New Scientist – February 4, 2023 issue:

How to tell if your immune system is weak or strong

New blood tests can reveal whether your immune system is fighting fit by looking at the balance of different immune cells, but there may be a simpler way of gauging your immune health

Inside the complex and extremely violent world of warring mongooses

Banded mongooses have long been used as a model of animal cooperation. Now, researchers in Uganda are starting to get to grips with the harsh realities of their long-running and bloody battles

How genetically engineered immune cells are beating some cancers

In some cases, it is now possible to genetically engineer the immune system to banish cancers like T-cell leukaemia that were previously unresponsive to treatments

Medicine: ‘Single Drop’ Blood Testing Advances

“Even more importantly, we’ve shown you can collect the blood drop at home and mail it into the lab,” said Michael Snyder, PhD, director of the Center for Genomics and Personalized Medicine and senior author on the research, which was published in Nature Biomedical Engineering on Jan. 19.

Stanford Medicine (January 19, 2023) – Researchers at Stanford Medicine have shown they can measure thousands of molecules — some of which are signals of health — from a single drop of blood.

Unlike finger-prick testing for diabetes, which measures a single type of molecule (glucose), multi-omics microsampling gives data about thousands of different molecules at once.

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A single drop of blood can yield measurements for thousands of proteins, fats and other biomarkers, researchers at Stanford Medicine found.

The new approach combines a microsampling device — a tool used to self-administer a finger prick — with “multi-omics” technologies, which simultaneously analyze a vast array of proteins, fats, by-products of metabolism and inflammatory markers.

Epigenetics & Aging: DNA Breakage & Repair Effects

Harvard Medical School – A 13-year international study in mice demonstrates that loss of epigenetic information, which influences how DNA is organized and regulated, can drive aging independently of changes to the genetic code itself.

It also shows that restoring the integrity of the epigenome reverses age-related symptoms.

Learn more at https://hms.harvard.edu/news/loss-epi…

Infographic: Obesity And Cardiovascular Disease

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Our new position paper with @worldheartfed summarises the relationship between obesity and cardiovascular disease (#CVD) mortality.

World Obesity Federation (January 2023) – The ongoing obesity epidemic represents a global public health crisis that contributes to poor health outcomes, reduced quality of life, and >2.8 million deaths each year. Obesity is relapsing, progressive, and heterogeneous. It is considered a chronic disease by the World Obesity Federation (WOF) and a chronic condition by the World Heart Federation (WHF).

People living with overweight/obesity are at greater risk for cardiovascular (CV) morbidity and mortality. Increased adiposity (body fat), particularly visceral/abdominal fat, is linked to CV risk and CV disease (CVD) via multiple direct and indirect pathophysiological mechanisms. The development of CVD is driven, in part, by obesity-related metabolic, endocrinologic, immunologic, structural, humoral, haemodynamic, and functional alterations.

Learn more: http://bit.ly/3THvOZa

Future Of Health: Lancet Magazine At 200 Years

The Lancet (January 2023) – For our 200th anniversary year we have identified five Spotlight subjects of particular importance. Watch as Richard Horton, Editor-in-Chief, and other Lancet Editors around the world outline these Spotlights and discuss priorities for the future of health.

The Lancet Infectious Diseases | Journal | ScienceDirect.com by Elsevier

This year, we draw attention to the most critical issues impacting health globally, the extraordinary people involved in tackling them, and the voices of those most impacted. For five Spotlights, we will run a programme of activities to bring these issues to life and convene the right people and resources in order to drive change in these areas.

Spotlight on Universal Health Coverage
Ensuring all populations globally have access to affordable, quality health care

Spotlight on Research for Health
Prioritising evidence to guide and inform decision making

Spotlight on Child and Adolescent Health
Prioritising the health needs of children and adolescents now

Spotlight on Health and Climate Change
Tackling climate change through the lens of human health

Spotlight on Mental Health
Implementing sustainable global mental health in a fragmenting world

Medical Review: ‘Single-Port Robotic Surgery’

Freethink – Robotics are helping make minimally invasive surgeries even less invasive. Case in point: single-port robotic surgery, a relatively new type of approach where a robotic system controlled by a human surgeon executes the procedure by making only one incision into the patient.

Although still relatively uncommon, single-port surgery has been gaining momentum in recent years. The benefits are noticeable. Compared to traditional surgery, single-port surgery might leave patients with shorter recovery times, less scarring, and overall better outcomes.

The technique is also transforming how surgeons think about and execute surgery itself. “It’s allowing us to do surgeries differently than we do with [multi-port surgery],” said Michael Stifelman, M.D., director of robotic surgery at Hackensack University Medical Center. “What every patient wants is to get back to their life. Single-port robotics is allowing us to get them to that point more quickly.”

Learn more about the future of single-port surgery in this episode of “Operation: Reimagine Surgery,” a Freethink original series produced in partnership with Intuitive, which created the world’s first commercially available robotic surgery system in the 1990s.

Health: Why Are Flu, RSV And Strep Surging In 2022?

Daniela Hernandez | WSJ – Getting the flu can increase the risk of getting a second infection, including strep throat. WSJ’S Daniela Hernandez explains the science behind that, plus what it means for the rest of the winter and how we can protect ourselves so the tripledemic doesn’t get worse.

Video timeline: 0:24 – Flu Damage 1:25 – Lower population immunity 2:03 – Who’s most vulnerable? 3:05 – How can we protect ourselves?

Review: Scripps California Institute For Biomedical Research (CALIBR) At 10 YRS

Calibr at Scripps Research is celebrating a major milestone, a decade of discovery. Take a look at the past 10 years of scientific innovation, and see what the next 10 years have in store.

The California Institute for Biomedical Research (Calibr) is a first-of-its-kind, nonprofit translational research institute dedicated to accelerating the next generation of medicines, celebrating its 10-year anniversary in 2022. Affiliated with Scripps Research—among the most innovative institutes worldwide—we spearhead drug discovery from a steady flow of pioneering science.

Our self-sustaining model encourages broad and bold exploration with far-reaching goals, yet rapid transition of our most successful, high-impact programs into the clinic. We pursue audacious and imaginative ideas—bridging scientific and technological advances to develop new medicines for unmet medical needs.

Learn more: https://www.scripps.edu/science-and-m…

Aging: Healthy Longevity Journal – December 2022

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December 2022 issue:

Long COVID and older people

Long COVID is a poorly understood condition, with a wide spectrum of effects on multiple body systems and variable presentation in different individuals. Long COVID is of particular concern among older people (ie, aged 65 years or older), who are at greater risk than younger people of persisting symptoms associated with COVID-19. In addition, COVID-19 might trigger or exacerbate chronic conditions that occur commonly in older people, such as cardiovascular diseases, respiratory diseases, neurodegenerative conditions, and functional decline.

Quantum Healthy Longevity for healthy people, planet, and growth

It is widely thought that lifespans are increasing globally. However, life expectancy has begun to stagnate in the UK, and is falling in more than 50 countries including the USA. Lifespan stagnation or decrease is a consequence of socioeconomic inequalities, lifestyle factors, and the COVID-19 pandemic. In the UK, the National Health Service spends vast sums treating chronic diseases; by some estimates, 40% of its costs go to treating preventable conditions.

Is age-related hearing loss a potentially modifiable risk factor for dementia?

The relationship of measures of age-related hearing loss such as pure-tone autiometry might not be as consistently associated with risk of dementia as previous studies have suggested. Peripheral age-related hearing loss has been posited as a midlife risk factor for dementia.