Category Archives: Reviews

Science: Researchers Build Crash-Resistant Flying ‘Beetlebot’ (Video)

Beetles are virtually crash resistant. Their wings fold up when they collide with objects, and then quickly spring back into place. That helps the insects stay on course and fly straight, rather than spiral to the ground, while exerting little energy. Researchers have now built a winged robot that mimics this capability.

The “beetlebot” keeps flying, even after it crashes into poles, researchers report this month in Science. The energy-efficient robot could even navigate narrow environments, such as collapsed buildings, to aid rescue missions, the team says.

Science Podcast: Shallow Pool Origins For Life On Earth, ‘Covidization’

How water chemistry is shifting researchers’ thoughts on where life might have arisen, and a new model to tackle climate change equitably and economically.

In this episode:

00:46 A shallow start to life on Earth?

It’s long been thought that life on Earth first appeared in the oceans. However, the chemical complexities involved in creating biopolymers in water has led some scientists to speculate that shallow pools on land were actually the most likely location for early life.

News Feature: How the first life on Earth survived its biggest threat — water

07:44 Coronapod

The COVID-19 pandemic has massively shifted the scientific landscape, changing research and funding priorities across the world. While this shift was necessary for the development of things like vaccines, there are concerns that the ‘covidization’ of research could have long-term impacts on other areas of research.

News: Scientists fear that ‘covidization’ is distorting research

20:45 Research Highlights

The Hayabusa2 mission successfully delivers a tiny cargo of asteroid material back to Earth, and a team in China claims to have made the first definitive demonstration of computational ‘quantum advantage’.

Nature News: Physicists in China challenge Google’s ‘quantum advantage’

22:38 Calculating carbon

Limiting carbon emissions is essential to tackling climate change. However, working out how to do this in a way that is fair to nations worldwide is notoriously difficult. Now, researchers have developed a model that gives some surprising insights in how to equitably limit carbon.

Research Article: Bauer et al.

News and Views: Trade-offs for equitable climate policy assessed

29:08 Briefing Chat

We discuss some highlights from the Nature Briefing. This time, bioluminescent Australian animals, and the collapse of the Arecibo telescope.

Medicine: ‘Three Critical Breakthroughs In Stroke Research’ (Yale Video)

Stroke is far more common than you might realize, affecting more than 795,000 people in the U.S. every year. It is a leading cause of death and long-term disability. Yet until now, treatment options have been limited, despite the prevalence and severity of stroke.

Not so long ago, doctors didn’t have much more to offer stroke victims than empathy, says Kevin Sheth, MD, Division Chief of Neurocritical Care and Emergency Neurology. “There wasn’t much you could do.” But that is changing. Recent breakthroughs offer new hope to patients and families. Beating the Clock Think of stroke as a plumbing problem in the brain. It occurs when there is a disruption of blood flow, either because of a vessel blockage (ischemic stroke) or rupture (hemorrhagic stroke).

In both cases, the interruption of blood flow starves brain cells of oxygen, causing them to become damaged and die. Delivering medical interventions early after a stroke can mean the difference between a full recovery and significant disability or death. Time matters. Unfortunately, stroke care often bottlenecks in the first stage: diagnosis. Sometimes, it’s a logistical issue; to identify the type, size, and location of a stroke requires MRI imaging, and the machinery itself can be difficult to access.

MRIs use powerful magnets to create detailed images of the body, which means they must be kept in bunker-type rooms, typically located in hospital basements. As a result, there is often a delay in getting MRI scans for stroke patients. Dr. Sheth collaborated with a group of doctors and engineers to develop a portable MRI machine. Though it captures the images doctors need to properly diagnose stroke, it uses a less powerful magnet. It is lightweight and can be easily wheeled to a patient’s bedside.

“It’s a paradigm shift – from taking a sick patient to the MRI to taking an MRI to a sick patient,” says Dr. Sheth. Stopping the Damage Once a stroke has been diagnosed, the work of mitigating the damage can begin. “Brain tissue is very vulnerable during the first hours after stroke,” says vascular neurologist Nils Petersen, MD. He and his team are using advanced neuro-monitoring technology to study how to manage a patient’s blood pressure in the very acute phase after a stroke.

Dr. Petersen’s research shows that optimal stroke treatment depends on personalization of blood pressure parameters. But calculating the ideal blood pressure for the minutes and hours after a patient has a stroke can be complicated. It depends on a variety of factors—it is not a one-size-fits-all scenario. Harnessing the Immune System Launching an inflammatory reaction is how the body responds to injury anywhere in the body – including the brain, following stroke. However, in this case, the resulting inflammation can sometimes cause even more damage.

But what if that immune response could be used to the patient’s advantage? “We’re trying to understand how we can harness the immune system’s knowledge about how to repair tissues after they’ve been injured,” says Lauren Sansing, MD, Academic Chief of the Division of Stroke and Vascular Neurology. Her team is working to understand the biological signals guiding the immune response to stroke.

That knowledge can then direct the development of targeted therapeutics for the treatment of stroke that minimize early injury and enhance recovery. “We want to be able to lead research efforts that change the lives of patients around the world,” says Dr. Sansing.

Learn about these developments and more in the video above.

For more information on aneurysms or #YaleMedicine, visit: https://www.yalemedicine.org/conditio…

Future Science: ‘Artificial Intelligence Everywhere’

December 4, 2020

Imagine a robot trained to think, respond, and behave using you as a model. Now imagine it assuming one of your roles in life, at home or perhaps at work. Would you trust it to do the right thing in a morally fraught situation?

That’s a question worth pondering as artificial intelligence increasingly becomes part of our everyday lives, from helping us navigate city streets to selecting a movie or song we might enjoy — services that have gotten more use in this era of social distancing. It’s playing an even larger cultural role with its use in systems for elections, policing, and health care.

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Literary Illustrators: ‘The Houses Of Sherlock Holmes’ By Matthew Rice

Dartmoor’s Baskerville Hall is one of the most famous country houses in English fiction. The arrival at its doors of Dr Watson, in the company of Sir Henry Baskerville, is a vivid piece of cinematic direction, artfully combining the Gothic horror tale with the more modern taste for detective thrillers.

Passing a ruined black-granite lodge, Watson and Baskerville go through the gates that are ‘a maze of fantastic tracery in wrought iron’ before reaching an avenue where ‘old trees shot their branches in a sombre tunnel’. The hall is a ‘heavy block’, with a projecting porch, its façade ‘draped in ivy’ within which the odd window or heraldic display can be seen.

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Art: Pablo Picasso’s ‘Girl Before A Mirror’ (Video)

This image of a young woman and her mirror reflection is riotous in color and chockablock with pattern. It is one of the last in a major series of canvases that Picasso created between 1931 and 1932. According to The Museum of Modern Art’s founding director, Alfred H. Barr, Jr., Picasso said he “preferred this painting to any of the others,” which speaks to the painting’s dazzling visual and thematic complexity. Its primary subject is the time-honored artistic theme of a woman before her mirror, reinvented in strikingly modern terms. The girl’s smoothly painted profile, in a delicately blushing pink-lavender, abuts a heavily built-up and garishly colored frontal view in yellow and red. Allusions to youth and old age, sun and moon, light and shadow are compressed into a single multivalent face.

Science Podcast: Covid-19 Vaccine Review And Side Effects, Restoring Vision

Staff Writer Meredith Wadman and host Sarah Crespi discuss what to expect from the two messenger RNA–based vaccines against COVID-19 that have recently released encouraging results from their phase III trials and the short-term side effects some recipients might see on the day of injection.

Sarah also talks with researcher Xing Chen, a project co-leader and postdoctoral scientist at the Netherlands Institute for Neuroscience, about using brain stimulation to restore vision. Researchers have known for about 70 years that electrical stimulation at certain points in the brain can lead to the appearance of a phosphene—a spot of light that appears not because there’s light there, but because of some other stimulation, like pressing on the eyeball. If electrical stimulation can make a little light appear, how about many lights? Can we think about phosphenes as pixels and draw a picture for the brain? How about a moving picture?