TEDx Talks (November 4, 2023) – Approximately 1.5 billion years ago, a lone bacterium found its way into a larger cell. The exchanges that transpired between the two are considered to have driven the evolution of this bacterium into the organelle we now call the mitochondrion.

Emerging research suggests that mitochondria are not simply the ‘powerhouses’ of the cell, but also function as cellular guardians against microbial intruders. Consequently, maintaining mitochondrial health is not only vital for our well-being, but may serve to protect us against infectious disease.

Dr. Lena Pernas started as a Max Planck Research Group Leader at the MPI Biology for Ageing (Cologne, Germany) in late 2018, where her lab investigates the organelle and metabolic dynamics of the host-pathogen interaction. Her lab will open its doors at UCLA in the Metabolism Research Theme in 2023.