Tag Archives: JAMA Clinical Reviews

Health: “The Effect Of Hearing Loss On Cognitive Decline” (JAMA Podcast)

JAMA Clinical ReviewsEven limited hearing loss might be associated with cognitive decline. If true, early intervention with hearing aids might help people have better cognitive performance. 

Michael Johns III, MD, online editor for JAMA Otolaryngology, speaks with Justin Golub, MD, MS, assistant professor of otolaryngology at Columbia University, whose research has shown that very mild hearing loss can be associated with cognitive disability.

Covid-19: Chloroquine + Azithromycin (Z-Pack) – “First Line” Treatment For Early Symptom Patients

WSJ Coronavirus Patients treated with Chloroquine + Azithromycin Z-Pack March 22 2020

JAMA Clinical Reviews LogoChloroquine was shown in 2004 to be active in vitro against SARS coronavirus but is of unproven efficacy and safety in patients infected with SARS-CoV-2. The drug’s potential benefits and risks for COVID-19 patients, without and with azithromycin, is discussed by Dr. David Juurlink, head of the Division of Clinical Pharmacology and Toxicology at Sunnybrook Health Sciences Centre in Toronto.

From Wall Street Journal article:

Our experience suggests that hydroxychloroquine, with or without a Z-Pak, should be a first-line treatment. Unfortunately, there is already a shortage of hydroxychloroquine. The federal government should immediately contract with generic manufacturers to ramp up production. Any stockpiles should be released.

As a matter of clinical practice, hydroxychloroquine should be given early to patients who test positive, and perhaps if Covid-19 is presumed—in the case of ill household contacts, for instance. It may be especially useful to treat mild cases and young patients, which would significantly decrease viral transmission and, as they say, “flatten the curve.”

Read Wall Street Journal article

Weight Loss: Medical Review Of “Keto, Atkins, and Pritikin Diets” (JAMA)

JAMA Clinical Studies PodcastThere are many named diets that receive a great deal of attention. But what are they and do they work? David Heber, MD, PhD, from the UCLA Center for Human Nutrition explains these diets.